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Who is the infector? General multi-type epidemics and real-time susceptibility processes

Published online by Cambridge University Press:  07 August 2019

Tom Britton*
Affiliation:
Stockholm University
Ka Yin Leung*
Affiliation:
Stockholm University
Pieter Trapman*
Affiliation:
Stockholm University
*
*Postal address: Department of Mathematics, Stockholm University, 106 91 Stockholm, Sweden.
*Postal address: Department of Mathematics, Stockholm University, 106 91 Stockholm, Sweden.
*Postal address: Department of Mathematics, Stockholm University, 106 91 Stockholm, Sweden.
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Abstract

We couple a multi-type stochastic epidemic process with a directed random graph, where edges have random weights (traversal times). This random graph representation is used to characterise the fractions of individuals infected by the different types of vertices among all infected individuals in the large population limit. For this characterisation, we rely on the theory of multi-type real-time branching processes. We identify a special case of the two-type model in which the fraction of individuals of a certain type infected by individuals of the same type is maximised among all two-type epidemics approximated by branching processes with the same mean offspring matrix.

Information

Type
Original Article
Copyright
© Applied Probability Trust 2019 
Figure 0

Figure 1. An example of $G'=(V,E')$ with $n=8$ and $K=2$. The vertices are labeled $a,b,\ldots,h$. Vertices of type 1 are represented by circles and vertices of type 2 by boxes. Contacts made by vertices of type 1 are represented by solid directed edges and contacts made by vertices of type 2 by dashed directed edges. The numeric values next to the edges are their lengths, each length reflecting the time $\eta(u,v)$ between infection of the tail u up until the first contact with the head $v,\,u,v \in \{a,b,\ldots,h\}$. In the figure we have placed nodes such that directed edges are pointing towards the right, but this is simply for convenience since there is no true spatial component in the underlying epidemic model.

Figure 1

Figure 2. An example of the construction of $\hat{G}(\ell)$ for $\ell =0$ (left), $\ell=1$ (middle), and $\ell =2$ (right). In each step one active vertex becomes explored. The edges with this vertex as head are identified, and if the tails of those edges were not yet part of the process $\{\hat{G}(\ell)\}$ before, those tails are active vertices. All edges with these active vertices as tails are identified. If the heads of those edges are newly added to the process then those heads are the passive vertices.

Figure 2

Figure 3. Illustration of (a part of) the susceptibility set of v in $G'=(V,E')$. Vertices of type 1 are represented by circles and vertices of type 2 are represented by squares. The part of the susceptibility set illustrated in the figure is the set connected to v through paths of edges with heads of type 1.