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Thinning and multilevel Monte Carlo methods for piecewise deterministic (Markov) processes with an application to a stochastic Morris–Lecar model

Published online by Cambridge University Press:  29 April 2020

Vincent Lemaire*
Affiliation:
Sorbonne University
MichÉle Thieullen*
Affiliation:
Sorbonne University
Nicolas Thomas*
Affiliation:
Sorbonne University
*
*Postal address: Laboratory of Probability, Statistics and Modeling (LPSM), UMR CNRS 8001, Sorbonne University–Campus Pierre et Marie Curie, Case 158, 4 place Jussieu, F-75252 Paris Cedex 5, France. Email addresses: vincent.lemaire@sorbonne-universite.fr, michele.thieullen@upmc.fr, nicolas.thomas@upmc.fr
*Postal address: Laboratory of Probability, Statistics and Modeling (LPSM), UMR CNRS 8001, Sorbonne University–Campus Pierre et Marie Curie, Case 158, 4 place Jussieu, F-75252 Paris Cedex 5, France. Email addresses: vincent.lemaire@sorbonne-universite.fr, michele.thieullen@upmc.fr, nicolas.thomas@upmc.fr
*Postal address: Laboratory of Probability, Statistics and Modeling (LPSM), UMR CNRS 8001, Sorbonne University–Campus Pierre et Marie Curie, Case 158, 4 place Jussieu, F-75252 Paris Cedex 5, France. Email addresses: vincent.lemaire@sorbonne-universite.fr, michele.thieullen@upmc.fr, nicolas.thomas@upmc.fr
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Abstract

In the first part of this paper we study approximations of trajectories of piecewise deterministic processes (PDPs) when the flow is not given explicitly by the thinning method. We also establish a strong error estimate for PDPs as well as a weak error expansion for piecewise deterministic Markov processes (PDMPs). These estimates are the building blocks of the multilevel Monte Carlo (MLMC) method, which we study in the second part. The coupling required by the MLMC is based on the thinning procedure. In the third part we apply these results to a two-dimensional Morris–Lecar model with stochastic ion channels. In the range of our simulations the MLMC estimator outperforms classical Monte Carlo.

Information

Type
Original Article
Copyright
© Applied Probability Trust 2020
Figure 0

Figure 1. Ten trajectories of the characteristics of the PDMP 2d-ML on [0,100]. (a) Membrane potential as a function of time: red curves, stochastic potential; black curve, deterministic potential. (b) Proportion of opened gates as a function of time: red curves, stochastic gates ($\theta/N_{\text{K}}$); black curve, deterministic gates (n). (c) Probability of opening a gate ($Q(x_t, \{\theta_t+1\})$) as a function of time. (d) Jump rate ($\lambda(x_t)$) as a function of t.

Figure 1

Table 1: Optimal parameters for the MLMC estimator (5.3).

Figure 2

Figure 2. Plots (a), (b), and (c) show the decay of ${\mathbb{E}} [(X_{h_l} - X_{h_{l-1}})^2]$ and ${\mathbb{E}}[\tilde X_{h_l} - \tilde X_{h_{l-1}})^2]$ (y-axis, $\log_M$ scale) as a function of l with $h_l = h \times M^{-(l-1)}$, $h=1$, $M=4$, for different values of the final time T: (a) $T=10$, (b) $T=20$, (c) $T=30$. For a visual guide, we added black solid lines with slopes $-1$ and $-2$.

Figure 3

Table 2: Results and parameters of the Monte Carlo estimator $Y^{\text{MC}}$. Estimated values of the structural parameters: $c_1=4.58$, $V_1=7.25$.

Figure 4

Table 3: Results and parameters of the multilevel Monte Carlo estimator $ Y^{\text{MLMC}}$. Estimated values of the structural parameters: $c_1=4.58$, $V_1=7.25$.

Figure 5

Table 4: Results and parameters of the multilevel Monte Carlo estimator $ \tilde Y^{\text{MLMC}}$ (Case 3). Estimated values of the structural parameters: $\tilde c_1=3.91$, $\tilde V_1=34.1$.

Figure 6

Figure 3. (a) Ratio of the complexities and (b) ratio of the CPU-times with respect to the complexity and CPU-time of the estimator $\tilde Y^{\text{MLMC}}$ as a function of the prescribed $\epsilon$ ($\log_2$ scale for the x-axis, $\log$ scale for the y-axis).