Obsessive-compulsive disorder (OCD) is a chronic and disabling condition of which the core features include unwanted and involuntary obsessional thoughts, impulses, or images (obsessions) that produce marked anxiety, typically accompanied by ritualised behaviours or mental acts (compulsions) that the person feels compelled to carry out in response to an obsession or based on inflexible rules that must be implemented (American Psychiatric Association [APA], 2013). The content of obsessions is somewhat idiosyncratic, although common themes include concerns regarding contamination with dirt or germs, concerns about symmetry, forbidden or taboo thoughts (e.g., sexual, religious, aggressive), and fears that harm may come to oneself or others (APA, 2013). Common compulsions include cleaning behaviours (e.g., hand washing), repeating, ordering and counting rituals, and checking behaviours (APA, 2013), with the latter exceeding 80% of clinical presentations (Ball, Baer, & Otto, Reference Ball, Baer and Otto1996). While compulsions are frequently performed to prevent, reduce, or eliminate distress or feared consequences (APA, 2013), the relief obtained through rituals is typically only temporary in nature, thus contributing to future ritual engagement (Deacon & Abramowitz, Reference Deacon and Abramowitz2004; Morrison, Reference Morrison1995). As a result, untreated symptoms often persist or increase over time, causing significant impairment in various areas of everyday functioning (e.g., social, academic, occupational) and reduced quality of life (de Silva, Reference de Silva, Menzies and de Silva2003; Koran, Thienemann, & Davenport, Reference Koran, Thienemann and Davenport1996; Skoog & Skoog, Reference Skoog and Skoog1999).
Childhood Diagnosis
Research suggests that OCD in children and adolescents is similar in presentation to OCD in adults (March & Leonard, Reference March and Leonard1996). As such, DSM-5 criteria for young people is the same as for adults, although children may not be able to express the purpose of their compulsive behaviours or mental acts (APA, 2013). Similar to adults, the most common obsessions in children include fear of contamination, fear of harm to oneself or others (e.g., death of a parent), and urges in relation to a need for order and precision (Shoenfelt & Weston, Reference Shoenfelt and Weston2007). Common compulsions include excessive washing and cleaning, checking, counting, repeating, touching, and straightening (Geller et al., Reference Geller, Biederman, Jones, Park, Schwartz, Shapiro and Coffey1998; March & Mulle, Reference March and Mulle1998). As with adults, children experience elevated anxiety and fear if the compulsive behaviour is interfered with or prevented, and can become both upset and oppositional. Parents, too, can experience anxiety in relation to their child's obsessions and compulsive behaviours and can become involved in the rituals, particularly by providing reassurance (Geller et al., Reference Geller, Biederman, Jones, Park, Schwartz, Shapiro and Coffey1998), or may alter their activities to accommodate the symptoms (Flessner et al., Reference Flessner, Freeman, Sapyta, Garcia, Franklin, March and Foa2011). As most children engage in age-appropriate obsessive and compulsive-like behaviours (e.g., bedtime rituals, superstitions, concerns about sameness) that fluctuate over time (Chansky, Reference Chansky2004; Keeley, Storch, Dhungana, & Geffken, Reference Keeley, Storch, Dhungana and Geffken2007; March & Mulle, Reference March and Mulle1998; Storch, Reference Storch2005), recognising deviation from normal developmental stages and daily patterns is essential to diagnosing paediatric OCD (Shoenfelt & Weston, Reference Shoenfelt and Weston2007). A comprehensive assessment with varying methods and sources of information is recommended (American Academy of Child and Adolescent Psychiatry [AACAP], 1998).
Prevalence Estimates in Adults
An evaluation of OCD was included in a large-scale nationally representative epidemiological survey of the United States (U.S.) adult population, the National Comorbidity Survey Replication (NCS-R) (Ruscio, Stein, Chiu, & Kessler, Reference Ruscio, Stein, Chiu and Kessler2010). Within this survey, a subsample of 2,073 participants was assessed for a diagnosis of lifetime DSM-IV OCD (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010). Results revealed lifetime and 12-month prevalence estimates for DSM-IV OCD of 2.3% and 1.2%, respectively. These findings were similar to those reported in prior studies, such as the Epidemiologic Catchment Area program measuring prevalence across five U.S. communities (lifetime prevalence ranging from 1.9% to 3.3%) (Karno, Golding, Sorenson, & Burnam, Reference Karno, Golding, Sorenson and Burnam1988), the Cross National Collaborative Group reporting data from seven countries (12-month prevalence ranging from 0.4 to 1.8%) (Weissman et al., Reference Weissman, Bland, Canino, Greenwald, Hwu, Lee and Wickramaratne1994), and the British National Psychiatric Morbidity Study (1-month prevalence of 1.1%) (Torres et al., Reference Torres, Prince, Psych, Bebbington, Bhugra, Brugha and Lewis2006). The survey also found that 28% of respondents experienced obsessions or compulsions at some time in their lives, with the most common being checking, hoarding, or ordering (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010). This data supports growing evidence that OCD symptoms are experienced by many individuals who do not meet diagnostic criteria, and complements other work proposing that the OCD spectrum may be more prevalent than once thought (e.g., Hollander, Stein, Broatch, Himelein, & Rowland, Reference Hollander, Stein, Broatch, Himelein and Rowland1997).
Prevalence Estimates in Children and Adolescents
Epidemiological studies conducted with child and adolescent populations report OCD prevalence rates ranging from 0.1% to 4% (Heyman et al., Reference Heyman, Fombonne, Simmons, Ford, Meltzer and Goodman2003), confirming that OCD in children is not a rare condition, as previously thought. For example, prevalence rates of OCD in young people from the U.S. have been reported at 0.2% (Costello et al., Reference Costello, Angold, Burns, Stangl, Tweed, Erkanli and Worthman1996), 1.9% (Flament et al., Reference Flament, Whitaker, Rapoport, Davies, Berg, Kalikow and Shaffer1988) and 2.9% (Valleni-Basile et al., Reference Valleni-Basile, Garrison, Jackson, Waller, McKeown, Addy and Cuffe1994). Similarly, prevalence rates of 0.2% in Switzerland (Steinhausen, Metzke, Meier, & Kannenberg, Reference Steinhausen, Metzke, Meier and Kannenberg1998) and 4% in New Zealand (Douglass, Moffitt, Dar, McGee, & Silva, Reference Douglass, Moffitt, Dar, McGee and Silva1995) have been reported. While providing valuable data, relatively few of these studies included prepubertal children (Heyman et al., Reference Heyman, Fombonne, Simmons, Ford, Meltzer and Goodman2003). The British Nationwide Survey of Child Mental Health was thus conducted with young people aged 5–15 years and reported an overall prevalence rate of 0.25% (Heyman et al., Reference Heyman, Fombonne, Simmons, Ford, Meltzer and Goodman2003). While at the lower end of the range, dividing OCD cases into age bands revealed an increase in the rate of OCD as age increased. This trend was in line with prior prevalence estimates, where higher rates had been reported in studies screening older age groups (e.g., Douglass et al., Reference Douglass, Moffitt, Dar, McGee and Silva1995; Flament et al., Reference Flament, Whitaker, Rapoport, Davies, Berg, Kalikow and Shaffer1988). Developmental variability has also been reported in the symptomatic expression of the disorder, with studies suggesting differences in the frequency of obsessions and compulsions across children, adolescents, and adults (Geller et al., Reference Geller, Biederman, Faraone, Agranat, Cradock, Hagermoser and Coffey2001).
Course of Illness in Adults
The mean age of onset of OCD is 19.5 years (APA, 2013), with very few new cases having an onset after age 30 (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010). Estimates indicate that two-thirds to 80% of adults with OCD report onset of symptoms before the age of 18 (Helbing & Ficca, Reference Helbing and Ficca2009; Pauls, Alsobrook, Goodman, Rasmussen, & Leckman, Reference Pauls, Alsobrook, Goodman, Rasmussen and Leckman1995; Riddle, Reference Riddle1998). Males tend to have onset of symptoms at an earlier age than females, with nearly a quarter showing onset before the age of 10 years (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010). Conversely, females show a swift growth in new cases after the age of 10, with the greatest rise during adolescence (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010). Adult studies report an equal gender spread or slightly more females (Geller, Reference Geller2006). Individuals who develop OCD experience the disorder on average for 8.9 years (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010). Without treatment, the course of OCD is generally chronic with symptoms that wax and wane over time and low remission rates (APA, 2013).
Course of Illness in Children and Adolescents
Childhood OCD is typically characterised by a chronic yet fluctuating course (Piacentini, Bergman, Keller, & McCracken, Reference Piacentini, Bergman, Keller and McCracken2003), with symptoms that come and go and also change over time (Geller et al., Reference Geller, Biederman, Jones, Park, Schwartz, Shapiro and Coffey1998). In a review of 11 studies that examined the clinical characteristics of OCD in children and adolescents, mean age of symptom onset was 10.3 years (Geller et al., Reference Geller, Biederman, Jones, Park, Schwartz, Shapiro and Coffey1998). However, diagnosis typically occurred 2.5 years after onset, with mean age at identification of the disorder at 13.2 years (Geller et al., Reference Geller, Biederman, Jones, Park, Schwartz, Shapiro and Coffey1998). In terms of gender, the majority of studies described a male predominance, with an average male-to-female ratio of 3:2 (Geller et al., Reference Geller, Biederman, Jones, Park, Schwartz, Shapiro and Coffey1998). Taken together, these reports suggest one peak in onset during childhood and another in early adulthood.
Impairment in Adults
As reported by various studies, OCD is characterised by significant impairment in various areas of everyday functioning (e.g., Matsunaga et al., Reference Matsunaga, Kiriike, Matsui, Oya, Iwasaki, Koshimune and Stein2002; Stein, Reference Stein2002). This was evidenced in the NCS-R survey (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010), which found that almost two-thirds (65%) of 12-month OCD cases reported severe impairment. As expected, impairment was highest for those in the clinically severe subgroup, with social functioning and relationship domains most affected (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010). Similarly, the British National Psychiatric Morbidity Study found that 59% of OCD sufferers experienced interference in social activities, and 75% experienced interference in work and regular activities (Torres et al., Reference Torres, Prince, Psych, Bebbington, Bhugra, Brugha and Lewis2006). Not surprisingly, OCD has been placed among the top 20 disorders causing significant disability for 18- to 44-year-olds (World Health Organization, 2001). In addition to the debilitating consequences of the disorder, OCD is also costly, with total cost estimates of $8.4 billion in the U.S. alone (DuPont, Rice, Shiraki, & Rowland, Reference DuPont, Rice, Shiraki and Rowland1995). Given these associated costs, in combination with its prevalence, OCD is considered a significant public health concern.
Impairment in Children and Adolescents
While OCD can be a profoundly disrupting illness for any individual, the impairment suffered in childhood and adolescence is significant, particularly given the development that occurs during these years. For example, Piacentini et al. (Reference Piacentini, Bergman, Keller and McCracken2003) found that almost 90% of children with OCD reported a significant OCD-related problem area (e.g., concentrating on schoolwork, getting ready for bed) in at least one functional domain (e.g., school, social, home). Not surprisingly, number of impairment ratings was significantly correlated with OCD severity (Piacentini et al., Reference Piacentini, Bergman, Keller and McCracken2003). These results confirm longstanding clinical observations that childhood OCD is associated with significant impairments in academic, home, and social functioning.
Comorbidity in Adults
OCD is associated with substantial comorbidity; for example, the NCS-R survey (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010) found that 90% of respondents with lifetime OCD met criteria for another lifetime DSM-IV disorder. Of these, the most common comorbid conditions were anxiety disorders (76%), followed by mood disorders (63%), impulse-control disorders (56%), and substance use disorders (39%). Comorbid tic disorders are also common among OCD sufferers (30%), as is obsessive-compulsive personality disorder (23% to 32%) (APA, 2013). OCD was found to begin at a later age than most comorbid anxiety disorders (Ruscio et al., Reference Ruscio, Stein, Chiu and Kessler2010), while an almost equal proportion of mood disorders occurred before (40.2%) and after (45.6%) OCD.
Comorbidity in Children and Adolescents
As with the adult OCD population, a number of comorbid psychiatric diagnoses have been reported for children and adolescents with OCD. For example, the British Nationwide Survey of Child Mental Health found that 76% of participants met criteria for a comorbid diagnosis. Specifically, comorbid diagnoses included anxiety disorders (52%), conduct disorder (44%), depression (20%), and eating disorders (4%) (Heyman et al., Reference Heyman, Fombonne, Simmons, Ford, Meltzer and Goodman2003). These data are in line with the findings of other epidemiological studies, where approximately two-thirds of young people with OCD had at least one additional psychiatric diagnosis (Zohar, Reference Zohar1999). High rates of comorbid tic disorders and disruptive behaviour disorders have also been reported (Geller, Reference Geller2006; Shoenfelt & Weston, Reference Shoenfelt and Weston2007).
The Treatment of OCD
Treatment in Adults
The leading psychological treatment for adults with OCD is cognitive-behavioural therapy (CBT) using exposure and response prevention (ERP) (Abramowitz, Brigidi, & Roche, Reference Abramowitz, Brigidi and Roche2001; Koran, Hanna, Nestadt, Hollander, & Simpson, Reference Koran, Hanna, Nestadt, Hollander and Simpson2007). During ERP, individuals with OCD are exposed to their feared obsessive stimuli/situation (e.g., dirt), while simultaneously withholding compulsive behaviours (e.g., washing). While studies have shown ERP to be an effective treatment for OCD (Fisher & Wells, Reference Fisher and Wells2005), patients often view it as demanding and aversive due to the prolonged and repeated exposure to stimuli (Abramowitz, Taylor, & McKay, Reference Abramowitz, Taylor and McKay2005), and as such, ERP is associated with high attrition rates. For example, Foa et al. (Reference Foa, Liebowitz, Kozak, Davies, Campeas, Franklin and Schmidt2005) reported an ERP refusal rate of 21% and dropout rate of 27% among adult outpatients with OCD. Cognitive techniques, on the other hand, may assist in engaging patients in ERP, and may also provide a useful alternate mode of treatment where ERP is not suitable (Abramowitz et al., Reference Abramowitz, Taylor and McKay2005; Salkovskis, Reference Salkovskis1999). Rather than focusing on habituation to anxiety, cognitive therapy typically uses techniques aimed at addressing dysfunctional belief domains (Abramowitz et al., Reference Abramowitz, Taylor and McKay2005; Steketee, Pigott, & Schemmel, Reference Steketee, Pigott and Schemmel2006). For example, cognitive restructuring and behavioural experiments are used to disconfirm unhelpful beliefs by generating alternate appraisals (Abramowitz et al., Reference Abramowitz, Taylor and McKay2005; Clark, Reference Clark2004). In a timely review, Julien, O'Connor, and Aardema (Reference Julien, O'Connor and Aardema2007) investigated the efficacy of cognitive therapy based on the appraisal model of OCD, which posits that six key belief domains contribute to OCD symptomatology (Obsessive Compulsive Cognitions Working Group [OCCWG], 1997). Results indicated that cognitive therapy was an effective treatment for OCD. Specifically, cognitive therapy and ERP showed comparable results on OCD symptom reduction, change in belief domains, treatment refusal, and drop-out rate (Julien et al., Reference Julien, O'Connor and Aardema2007), with one study finding a significantly greater percentage of recovered patients after cognitive therapy (Van Oppen, Hoekstra, & Emmelkamp, Reference Van Oppen, Hoekstra and Emmelkamp1995). Difficulties in comparing cognitive therapy with ERP, however, are thought to be considerable given the substantial overlap that often occurs in clinical settings and treatment studies (Abramowitz, Franklin, & Foa, Reference Abramowitz, Franklin and Foa2002; Fama & Wilhelm, Reference Fama, Wilhelm, Abramowitz and Houts2005).
To examine the efficacy of ERP, cognitive therapy, and their combination, a recent meta-analysis was conducted and found that CBT (encompassing cognitive techniques, behavioural techniques, acceptance/mindfulness, or a combination of these) resulted in better outcomes at both posttreatment and follow-up as compared to control conditions, with no significant differences between cognitive therapy and ERP (Olatunji, Davis, Powers, & Smits, Reference Olatunji, Davis, Powers and Smits2013). This finding was consistent with previous meta-analyses which found that CBT was very effective in producing OCD symptom reduction (Abramowitz, Reference Abramowitz1997; Rosa-Alcázar, Sánchez-Meca, Gómez-Conesa, & Marín-Martínez, Reference Rosa-Alcázar, Sánchez-Meca, Gómez-Conesa and Marín-Martínez2008). Comparable effects were also reported for different intervention types, including cognitive therapy, ERP, and a combination of the two (Abramowitz, Reference Abramowitz1997; Abramowitz et al., Reference Abramowitz, Franklin and Foa2002; Eddy, Dutra, Bradley, & Westen, Reference Eddy, Dutra, Bradley and Westen2004; Rosa-Alcázar et al., Reference Rosa-Alcázar, Sánchez-Meca, Gómez-Conesa and Marín-Martínez2008), suggesting little difference between variations of CBT.
Pharmacotherapy in the form of serotonin reuptake inhibitors (SRIs) is another widely used treatment for OCD in adults, considered first-line alongside behavioural therapy (Koran et al., Reference Koran, Hanna, Nestadt, Hollander and Simpson2007; Lambert, Reference Lambert2008). It is unclear, however, whether ERP and CBT show superior treatment outcomes to pharmacotherapy, with some studies reporting ERP as the preferable treatment (e.g., Foa et al., Reference Foa, Liebowitz, Kozak, Davies, Campeas, Franklin and Schmidt2005; Nakatani et al., Reference Nakatani, Nakagawa, Nakao, Yoshizato, Nabeyama, Kudo and Kawamoto2005), and others finding no significant difference between CBT and pharmacotherapy (e.g., Belotto-Silva et al., Reference Belotto-Silva, Diniz, Malavazzi, Valério, Fossaluza, Borcato and Shavitt2012; Sousa, Isolan, Oliveira, Manfro, & Cordioli, Reference Sousa, Isolan, Oliveira, Manfro and Cordioli2006). However, limitations are present in the use of pharmacotherapy, including ambivalence about taking medication, risk of unpleasant side effects that increases at higher dosages (Poppe et al., Reference Poppe, Müller, Greil, Walder, Grohmann and Stübner2016), and very high relapse rates upon stopping medication (Dougherty, Rauch, & Jenike, Reference Dougherty, Rauch and Jenike2004).
Following from this, psychological treatments may be preferable to patients and are often recommended alongside SRI treatment to reduce relapse rates (Dougherty et al., Reference Dougherty, Rauch and Jenike2004). For example, Danger Ideation Reduction Therapy (DIRT) has shown promising results as a cognitive treatment for OCD and focuses on reducing threat expectancies through structured psychoeducation and cognitive therapy (Jones & Menzies, Reference Jones and Menzies1997b, Reference Jones and Menzies1998). While initially designed to treat people with contamination and washing symptoms (Jones & Menzies, Reference Jones and Menzies1997b, Reference Jones and Menzies1998; Krochmalik, Jones, Menzies, & Kirkby, Reference Krochmalik, Jones, Menzies and Kirkby2004), DIRT has since been adapted for the treatment of obsessive-compulsive checking (Vaccaro, Jones, Menzies, & St Clare, Reference Vaccaro, Jones, Menzies and St Clare2010), with a recent study finding larger effect sizes related to changes in OCD severity for DIRT compared to ERP at posttreatment and 6-month follow-up (Vaccaro, Jones, Menzies, & Wootton, Reference Vaccaro, Jones, Menzies and Wootton2014). Such results provide support for the use of cognitively based treatments in OCD.
Issues in Adult Treatment
Despite the existence of treatments with demonstrated efficacy for OCD, it is thought that OCD remains under-recognised in individuals of all ages (Heyman et al., Reference Heyman, Fombonne, Simmons, Ford, Meltzer and Goodman2003). Many individuals with OCD are undiagnosed or misdiagnosed and do not access suitable treatment (Grabill et al., Reference Grabill, Merlo, Duke, Harford, Keeley, Geffken and Storch2008). Numerous individuals diagnosed with OCD also fail to receive adequate treatment (Mataix-Cols & Marks, Reference Mataix-Cols and Marks2006); for example, Ruscio et al. (Reference Ruscio, Stein, Chiu and Kessler2010) found that while almost three-quarters (72.7%) of lifetime OCD cases received treatment, less than one-third (29.2%) received treatment specific to OCD. Of the patients who receive treatment, research indicates that while the majority make advances over the course of treatment, a large number continue to experience significant residual symptoms at the conclusion of treatment (Boschen & Drummond, Reference Boschen and Drummond2012; Fisher & Wells, Reference Fisher and Wells2005). For example, Fisher and Wells (Reference Fisher and Wells2005) found that while ERP and cognitive therapy resulted in improvement in 75% and 61% of patients respectively, only a small portion were asymptomatic at the end of treatment (21–25%). Further, a meta-analysis of 16 controlled ERP treatment studies reported average symptom reduction at 48%, indicating that a large portion of OCD individuals continued to experience symptoms after treatment (Abramowitz et al., Reference Abramowitz, Franklin and Foa2002). Similar results are evident for pharmacotherapy treatment, with a substantial amount of OCD individuals either not responding to treatment or showing a partial or incomplete response despite having had a sufficient dosage and treatment timeframe (Bloch, McGuire, Landeros-Weisenberger, Leckman, & Pittenger, Reference Bloch, McGuire, Landeros-Weisenberger, Leckman and Pittenger2010; Fineberg, Brown, Reghunandanan, & Pampaloni, Reference Fineberg, Brown, Reghunandanan and Pampaloni2012). Given the shortcomings of current treatment methods, additional controlled studies investigating the mechanisms of treatment change would likely prove helpful, as would the development of new treatments, perhaps designed for common OCD symptoms presentations as seen in the DIRT program and its variations. Overall, these research findings indicate substantial room for improvement in the treatment of OCD.
Treatment in Children and Adolescents
Empirical studies support the use of individual, group, and family CBT in reducing symptomatology and impairment for children and adolescents suffering from OCD (Abramowitz, Whiteside, & Deacon, Reference Abramowitz, Whiteside and Deacon2006; Barrett, Farrell, Pina, Peris, & Piacentini, Reference Barrett, Farrell, Pina, Peris and Piacentini2008; March, Reference March1995; March et al., Reference March, Foa, Gammon, Chrisman, Curry, Fitzgerald and Rynn2004; Williams, Salkovskis, Forrester, & Allsopp, Reference Williams, Salkovskis, Forrester and Allsopp2002). For instance, Barrett, Farrell, Dadds, and Boulter (Reference Barrett, Farrell, Dadds and Boulter2005) found that 70% of child and adolescent participants receiving individual CBT and 84% of those receiving group CBT maintained their improvements at 12- and 18-months follow-up and no longer met criteria for a diagnosis of OCD. Similarly, a recent systematic review of individual CBT for paediatric OCD found that CBT was superior to wait-list and placebo therapy (Skarphedinsson et al., Reference Skarphedinsson, Hanssen-Bauer, Kornør, Heiervang, Landrø, Axelsdottir and Ivarsson2015), while a recent meta-analysis reported large effect sizes for CBT (incorporating ERP, cognitive strategies, and relapse prevention) in reducing obsessive-compulsive (OC) symptoms (Rosa-Alcázar et al., Reference Rosa-Alcázar, Sánchez-Meca, Rosa-Alcázar, Iniesta-Sepúlveda, Olivares-Rodríguez and Parada-Navas2015). Pharmacotherapy with serotonin reuptake inhibitors is also supported in the literature as an effective treatment for reducing OCD symptoms (Cook et al., Reference Cook, Wagner, March, Biederman, Landau, Wolkow and Messig2001; Geller et al., Reference Geller, Wagner, Emslie, Murphy, Carpenter, Wetherhold and Gardiner2004; Ivarsson et al., Reference Ivarsson, Skarphedinsson, Kornør, Axelsdottir, Biedilæ, Heyman and March2015; Riddle et al., Reference Riddle, Reeve, Yaryura-Tobias, Yang, Claghorn, Gaffney and Pigott2001), although studies typically report larger effect sizes and higher rates of clinical improvement for a combination of CBT and SRI medication or CBT alone (Abramowitz et al., Reference Abramowitz, Whiteside and Deacon2006; Ivarsson et al., Reference Ivarsson, Skarphedinsson, Kornør, Axelsdottir, Biedilæ, Heyman and March2015; March et al., Reference March, Foa, Gammon, Chrisman, Curry, Fitzgerald and Rynn2004; Romanelli, Wu, Gamba, Mojtabai, & Segal, Reference Romanelli, Wu, Gamba, Mojtabai and Segal2014; Sánchez-Meca, Rosa-Alcázar, Iniesta-Sepúlveda, & Rosa-Alcázar, Reference Sánchez-Meca, Rosa-Alcázar, Iniesta-Sepúlveda and Rosa-Alcázar2014). Current guidelines thus recommend that CBT be the first line of treatment for paediatric OCD, with the addition of SRI medication indicated for those with moderate to severe OCD or those who show a poor clinical response to treatment (Geller & March, Reference Geller and March2012; Shoenfelt & Weston, Reference Shoenfelt and Weston2007). Knowledge of the family system is also paramount in treating paediatric OCD, as growing literature supports the adverse effect of family factors (e.g., conflict, blame, poor cohesion, accommodation of OCD symptoms) on CBT treatment response in paediatric OCD (Flessner et al., Reference Flessner, Freeman, Sapyta, Garcia, Franklin, March and Foa2011; Garcia et al., Reference Garcia, Sapyta, Moore, Freeman, Franklin, March and Foa2010; Merlo, Lehmkuhl, Geffken, & Storch, Reference Merlo, Lehmkuhl, Geffken and Storch2009; Murphy & Flessner, Reference Murphy and Flessner2015; Peris et al., Reference Peris, Sugar, Bergman, Chang, Langley and Piacentini2012; Storch et al., Reference Storch, Björgvinsson, Riemann, Lewin, Morales and Murphy2010).
Issues in Child and Adolescent Treatment
In addition to the growing need for treatment strategies designed for more complex child and adolescent OCD cases (Garcia et al., Reference Garcia, Sapyta, Moore, Freeman, Franklin, March and Foa2010), a large number of young people fail to respond to treatment or only show a partial response (Barrett et al., Reference Barrett, Farrell, Pina, Peris and Piacentini2008; Ginsburg, Kingery, Drake, & Grados, Reference Ginsburg, Kingery, Drake and Grados2008). For example, a large treatment study reported that almost 50% of young people continued to experience ongoing symptoms at the end of treatment (March et al., Reference March, Foa, Gammon, Chrisman, Curry, Fitzgerald and Rynn2004). Further, a review of the treatment literature for child and adolescent OCD found exposure-based CBT remission rates ranging from 40% to 85% (Barrett et al., Reference Barrett, Farrell, Pina, Peris and Piacentini2008), indicating significant room for improvement in the treatment of paediatric OCD. Additional research is thus needed with the goal of better understanding factors related to the child, family and treatment processes that interfere with treatment response and how treatment can be best tailored to suit individual needs.
Cognitive Processes in OCD
Cognitive Models of OCD
Cognitive models of OCD theorise that individuals suffering from the disorder hold certain beliefs that lead them to interpret the presence and content of intrusive thoughts in ways conducive to anxiety and distress (OCCWG, 1997). For example, (Salkovskis, Reference Salkovskis1985, Reference Salkovskis1989) proposed that individuals with OCD interpret (or ‘appraise’) intrusive thoughts with a responsibility bias, leading to anxiety and distress. This interpretative feature of the disorder has thus been emphasised as important to both its development and maintenance (e.g., Rachman, Reference Rachman1997; Salkovskis, Shafran, Rachman, & Freeston, Reference Salkovskis, Shafran, Rachman and Freeston1999). Further, models propose that the compulsive behaviours exhibited in OCD are a direct result of the distress caused by intrusive thoughts and their accompanying appraisals (e.g., Salkovskis, Reference Salkovskis1985, Reference Salkovskis1989). Thus, targeting cognitive appraisals either directly or indirectly is central to positive treatment outcome (Rachman, Reference Rachman1997). There is debate, however, as to which types of appraisals are most fundamental to this disorder, as evidenced by the differing beliefs and cognitive processes hypothesised throughout the models, such as responsibility, overestimation of threat, and thought-action fusion (Salkovskis, Reference Salkovskis1985, Reference Salkovskis1989; Shafran, Thordarson, & Rachman, Reference Shafran, Thordarson and Rachman1996; Van Oppen & Arntz, Reference Van Oppen and Arntz1994). In an effort to collate the emerging research on cognitive models and develop a standardised assessment tool of cognition, a group of prominent OCD researchers came together and agreed that six types of appraisals are common among individuals with OCD and likely to be important in the escalation of intrusive thoughts into obsessions (OCCWG, 1997). In line with earlier theorists, the proposed model suggests that the interpretation of intrusive thoughts is in line with pre-existing maladaptive beliefs held by the individual, which develop in childhood as a result of particular experiences (e.g., exposure to heightened responsibility, overprotection, serious misfortune). Thus, the central way to distinguish between individuals with and without OCD is not the presence of intrusive thoughts, but rather the existence of OCD-related dysfunctional assumptions (Julien et al., Reference Julien, O'Connor and Aardema2007). Without these beliefs, intrusive thoughts would be discounted with greater ease and not become obsessions (Salkovskis, Reference Salkovskis1985, Reference Salkovskis1989).
Appraisal models of OCD are thus based on two main ideas. First, the occurrence of intrusive thoughts is within standard human experience, and second, intrusive thoughts only become obsessions when they are interpreted in a particular way (Julien et al., Reference Julien, O'Connor and Aardema2007; Salkovskis, Reference Salkovskis1999). To provide support for these ideas, research should clearly demonstrate that: (1) non-clinical individuals experience intrusive thoughts that are related to clinical obsessions and differ from negative automatic thoughts (Purdon & Clark, Reference Purdon and Clark1993); (2) individuals with OCD show elevated ratings on the obsessive belief domains compared to non-clinical persons and individuals with non-OCD anxiety disorders (Tolin, Worhunsky, & Maltby, Reference Tolin, Worhunsky and Maltby2006); and (3) a clear relationship exists between obsessive beliefs and OCD symptom subtypes (e.g., washing, checking) (Tolin et al., Reference Tolin, Worhunsky and Maltby2006). The last point appears particularly important in asserting a causal role of these belief domains in the development of compulsive behaviours, including assessment of this relationship using experimental research designs.
In regard to the first premise, it has been suggested that non-clinical adults experience intrusive thoughts with content comparable to that of clinical obsessions (e.g., Freeston & Ladouceur, Reference Freeston and Ladouceur1993; Parkinson & Rachman, Reference Parkinson and Rachman1981; Rachman, Reference Rachman1971, Reference Rachman1997; Salkovskis, Reference Salkovskis1989). This has been supported by research showing that a large number of non-clinical individuals experience intrusive thoughts with content similar to those found in OCD, although they differ in various ways such as duration, frequency, unpleasantness, and intensity (Morillo, Belloch, & García-Soriano, Reference Morillo, Belloch and García-Soriano2007; Rachman & de Silva, Reference Rachman and de Silva1978). To further investigate this premise, Julien et al. (Reference Julien, O'Connor and Aardema2007) conducted a review of the relevant literature exploring the occurrence of intrusive thoughts in non-clinical samples. Support was found for the universality of intrusive thoughts, with results showing that 72% to 100% of non-clinical adults experienced intrusive thoughts at some point in their life (Julien et al., Reference Julien, O'Connor and Aardema2007). Given these findings, it was concluded that OCD cannot be sufficiently understood by the occurrence of intrusive thoughts alone (Julien et al., Reference Julien, O'Connor and Aardema2007), OCD cannot be sufficiently understood by the occurrence of intrusive thoughts alone (Julien et al., Reference Julien, O'Connor and Aardema2007). Rather, the distinguishing variable appears to be the appraisal of the occurrence and content of the thoughts (Julien et al., Reference Julien, O'Connor and Aardema2007).
Research Examining Obsessive Belief Domains in Adults
Various authors have conducted research examining one or more of the six belief domains identified by the OCCWG (1997). These include inflated responsibility, overestimation of threat, perfectionism, intolerance of uncertainty, overimportance of thoughts, and a need to control thoughts. While some researchers endorse one cognitive domain over others (e.g., inflated responsibility), the OCCWG (1997) asserts that each cognitive domain is of fundamental importance in the escalation of intrusive thoughts into obsessions, although they have since been combined into three belief domains due to significant overlap (responsibility/threat overestimation, perfectionism/certainty, and importance/control of thoughts) (OCCWG, 2005). For the purpose of this review, the six belief domains will be summarised individually, with focus primarily on studies assessing the belief domains separately. Focus will be placed on exploring (1) whether individuals with OCD show elevated ratings on the obsessive belief domains compared to non-clinical persons and individuals with non-OCD anxiety disorders, and (2) whether a relationship exists between the obsessive beliefs and OCD symptom subtypes.
Inflated responsibility
As defined by the OCCWG (2001, pp. 1002, 1003), inflated responsibility refers to ‘the belief that one has power that is pivotal to bring about or prevent subjectively crucial negative outcomes perceived as essential to prevent and that may have consequences in the real world and/or at a moral level’. This influential construct has received attention both as a singular entity and alongside other belief domains (e.g., Freeston, Rhéaume, & Ladouceur, Reference Freeston, Rhéaume and Ladouceur1996; OCCWG, 1997, 2005; Rachman, Reference Rachman1993; Rhéaume, Ladouceur, Freeston, & Letarte, Reference Rhéaume, Ladouceur, Freeston and Letarte1995; Salkovskis, Reference Salkovskis1985, Reference Salkovskis1989, Reference Salkovskis, Shafran, Rachman and Freeston1999; Salkovskis, Richards, & Forrester, Reference Salkovskis, Richards and Forrester1995; Van Oppen & Arntz, Reference Van Oppen and Arntz1994; Williams et al., Reference Williams, Salkovskis, Forrester and Allsopp2002). Salkovskis (Reference Salkovskis1985, Reference Salkovskis1989) originally proposed that intrusive thoughts are interpreted in a way that indicates personal responsibility for possible harm or negative consequences occurring to the self or to others. This may involve acts of omission (failure to prevent harm) or acts of commission (causing harm) (Wroe & Salkovskis, Reference Wroe and Salkovskis2000). A causal role is assigned to responsibility appraisals, whereby feeling personally responsible for preventing harm will directly result in compulsive behaviours aimed to decrease discomfort and the risk of a negative outcome (Salkovskis et al., Reference Salkovskis, Richards and Forrester1995). Following Salkovskis’ (Reference Salkovskis1985, Reference Salkovskis1989) proposal, the role of responsibility was highlighted by the OCCWG (1997) among the aforementioned five other belief domains, and later combined with threat estimation (OCCWG, 2005).
Within the substantial body of research focused on exploring the role of inflated responsibility appraisals in OCD, the large majority of studies are correlational and results appear mixed. First, several studies have found that responsibility beliefs are elevated in OCD patients compared to normal controls (Cartwright-Hatton & Wells, Reference Cartwright-Hatton and Wells1997; Freeston, Ladouceur, Gagnon, & Thibodeau, Reference Freeston, Ladouceur, Gagnon and Thibodeau1993; Kumar, Sharma, Kandavel, & Reddy, Reference Kumar, Sharma, Kandavel and Reddy2012; Niemeyer, Moritz, & Pietrowsky, Reference Niemeyer, Moritz and Pietrowsky2013; OCCWG, 2001, 2003; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Steketee, Frost, & Cohen, Reference Steketee, Frost and Cohen1998), especially those with checking compulsions (Foa, Amir, Bogert, Molnar, & Przeworski, Reference Foa, Amir, Bogert, Molnar and Przeworski2001; Foa, Sacks, Tolin, Prezworski, & Amir, Reference Foa, Sacks, Tolin, Prezworski and Amir2002). For example, Steketee et al. (Reference Steketee, Frost and Cohen1998) and Niemeyer et al. (Reference Niemeyer, Moritz and Pietrowsky2013) found that OCD participants scored higher than control participants on responsibility belief domains. This was further supported by a recent meta-analysis of 22 studies that found a large effect size favouring OCD patients compared to healthy controls (Pozza & Dèttore, Reference Pozza and Dèttore2014b). Responsibility beliefs have also been shown to correlate with obsessive compulsive (OC) symptoms (Niemeyer et al., Reference Niemeyer, Moritz and Pietrowsky2013; Steketee et al., Reference Steketee, Frost and Cohen1998) and significantly predict OC symptoms after controlling for metacognition (Niemeyer et al., Reference Niemeyer, Moritz and Pietrowsky2013). These associations are also evident in studies utilising non-clinical samples showing a link between responsibility and OC symptoms (Freeston et al., Reference Freeston, Ladouceur, Gagnon and Thibodeau1993; Gwilliam, Wells, & Cartwright‐Hatton, Reference Gwilliam, Wells and Cartwright‐Hatton2004; Myers, Fisher, & Wells, Reference Myers, Fisher and Wells2008; Parrish & Radomsky, Reference Parrish and Radomsky2011; Rhéaume, Freeston, Dugas, Letarte, & Ladouceur, Reference Rhéaume, Freeston, Dugas, Letarte and Ladouceur1995; Wilson & Chambless, Reference Wilson and Chambless1999). For example, Parrish and Radomsky (Reference Parrish and Radomsky2011) found that higher levels of responsibility were associated with higher anxiety and compulsive urges in a series of experimental vignettes. Similarly, Wilson and Chambless (Reference Wilson and Chambless1999) and Rhéaume et al. (Reference Rhéaume, Freeston, Dugas, Letarte and Ladouceur1995) found that inflated responsibility beliefs were significantly associated with OC symptoms in non-clinical adults and were a significant predictor of OC symptoms. However, such results are not found consistently; for example, recent research on student samples has found that responsibility is not a strong predictor of OC symptoms (Fitch & Cougle, Reference Fitch and Cougle2013; McKay et al., Reference McKay, Kim, Taylor, Abramowitz, Tolin, Coles and Olatunji2014) and does not predict OC symptoms when other belief domains are controlled for (Gwilliam et al., Reference Gwilliam, Wells and Cartwright‐Hatton2004; Myers et al., Reference Myers, Fisher and Wells2008; Myers & Wells, Reference Myers and Wells2005; Tolin, Woods, & Abramowitz, Reference Tolin, Woods and Abramowitz2003), which is surprising given its prominence in cognitive models of OCD (Salkovskis, Reference Salkovskis1985, Reference Salkovskis1989; Salkovskis et al., Reference Salkovskis, Shafran, Rachman and Freeston1999).
A similar picture is evident when comparing OCD patients and patients with other anxiety disorders. While some studies report that responsibility beliefs are specific to individuals with OCD, others report that responsibility may be related to anxiety in general, if at all. For example, while Foa et al. (Reference Foa, Amir, Bogert, Molnar and Przeworski2001), the OCCWG (2003), and Steketee et al. (Reference Steketee, Frost and Cohen1998) found stronger responsibility beliefs in individuals with OCD compared to those with other anxiety disorders, McKay et al. (Reference McKay, Kim, Taylor, Abramowitz, Tolin, Coles and Olatunji2014) and Tolin et al. (Reference Tolin, Worhunsky and Maltby2006) found that OCD patients did not endorse responsibility more strongly than either anxious or non-clinical controls. Similarly, Cartwright-Hatton and Wells (Reference Cartwright-Hatton and Wells1997) found that OCD patients did not endorse responsibility beliefs more strongly than patients with generalised anxiety disorder (GAD), although both patient groups showed elevated responsibility beliefs compared to non-clinical controls. Results such as these have led authors to conclude that inflated responsibility may be common among individuals with anxiety disorders, although OCD may be higher on the continuum (Foa et al., Reference Foa, Amir, Bogert, Molnar and Przeworski2001). Further, some authors suggest that responsibility may only differ between OCD and anxious patients and predict OCD symptoms (e.g., checking) when combined with threat estimation (Rachman, Reference Rachman2002). Following from this, a recent meta-analysis of 58 studies conducted by Pozza and Dèttore (Reference Pozza and Dèttore2014a) found that responsibility was more strongly associated with OCD than depression symptoms, but not anxiety disorder symptoms. Further, when analyses were limited to responsibility measures designed by the OCCWG, the relationship between responsibility and OCD was not stronger than that of depression or anxiety disorders. The authors thus concluded that the specificity of responsibility to OCD was at present questionable, and causal inferences on the role of responsibility in OCD could not be made due to the cross-sectional nature of the studies.
In terms of experimental research, various studies have been conducted to examine the effect of inflated responsibility on OCD symptoms and processes (e.g., Arntz, Voncken, & Goosen, Reference Arntz, Voncken and Goosen2007; Ladouceur, Rhéaume, & Aublet, Reference Ladouceur, Rhéaume and Aublet1997; Ladouceur et al., Reference Ladouceur, Rhéaume, Freeston, Aublet, Jean, Lachance and de Pokomandy-Morin1995; Mancini, D'Olimpio, & Cieri, Reference Mancini, D'Olimpio and Cieri2004). For example, Lopatka and Rachman (Reference Lopatka and Rachman1995) and Shafran (Reference Shafran1997) manipulated responsibility with OCD patients and found that increases in perceived responsibility resulted in significant elevations in discomfort and the urge to engage in compulsive checking/neutralising. Similarly, Mancini et al. (Reference Mancini, D'Olimpio and Cieri2004) found increased doubt, error preoccupation, checking, hesitations, and trial latency for their high compared to low responsibility condition with an unselected sample. Not all studies, however, showed such results. For example, Jones and Menzies (Reference Jones and Menzies1997a) found that urges to neutralise anxiety, time spent neutralising, and ‘time in dirt’ were associated with danger (i.e., threat) but not responsibility appraisals in an OCD sample. To compare such studies and synthesise results, a recent systematic review was conducted (Mantz & Abbott, Reference Mantz and Abbott2017). Fourteen studies using adult samples were identified, with the earliest published in 1995 and the most recent published in 2014. Of the five studies with OCD patients, only two included a control group to provide a frame of reference for the effects found with OCD participants. The authors found that while responsibility manipulations had a consistently adverse effect on responsibility and threat appraisals, the effect on self and observer-rated variables (e.g., urge to check, neutralising behaviours) was inconsistent, with mixed results. Further, the effects of responsibility were generally not significantly greater for OCD participants. Thus, it was concluded that the specificity of responsibility to OCD was at present unclear and that support for a responsibility bias in OCD was inconclusive. The need to explore other appraisal types (e.g., uncertainty, perceived threat, control) was also emphasised, particularly given the strong overlap with findings showing threat appraisals as an important contributor to OCD symptomatology.
Overestimation of threat
As defined by the OCCWG (2001, p. 1004), overestimation of threat refers to ‘an exaggerated belief about the probability (likelihood) or severity (cost) of harm’. This belief domain has received attention from many theorists and clinicians who identify threat cognitions as common among individuals with OCD and important in the conceptualisation of the disorder (Beck, Emery, & Greenberg, Reference Beck, Emery and Greenberg1985; Carr, Reference Carr1974; Foa & Kozak, Reference Foa, Kozak, Tuma and Maser1985; Jones & Menzies, Reference Jones and Menzies1997a; Marks, Reference Marks1987; McFall & Wollersheim, Reference McFall and Wollersheim1979; OCCWG, 1997, 2001, 2003; Rachman & Hodgson, Reference Rachman and Hodgson1980; Reed, Reference Reed1985; Van Oppen & Arntz, Reference Van Oppen and Arntz1994; Woods, Frost, & Steketee, Reference Woods, Frost and Steketee2002). Different components of threat have been identified, including overestimations of personal vulnerability and overestimation of general threat, among others, with debate as to which is most important in threat estimation (Moritz & Jelinek, Reference Moritz and Jelinek2009). For example, a person with OCD may wash their hands excessively after touching a door handle due to an overestimation of the objective probability of contamination, or an overestimation of personal vulnerability to experience a negative event (Moritz & Jelinek, Reference Moritz and Jelinek2009). If the primary issue lies in an inaccurate overestimation of general threat (i.e., base rates), providing corrective information may well improve OCD symptoms (Jones & Menzies, Reference Jones and Menzies1997b). This is evidenced in DIRT, an effective treatment for OCD washing and checking symptoms that focuses on reducing threat expectancies through structured psychoeducation and cognitive therapy (Jones & Menzies, Reference Jones and Menzies1998; Krochmalik et al., Reference Krochmalik, Jones, Menzies and Kirkby2004; Vaccaro et al., Reference Vaccaro, Jones, Menzies and Wootton2014). Additionally, individuals with OCD may overestimate the consequences of negative events instead of or in addition to overestimating the probability of such events occurring (Moritz & Jelinek, Reference Moritz and Jelinek2009). For example, individuals with fear of contamination might overestimate the probability of contracting an illness, as well as the severity of the illness that occurs. Perceived control and ability to cope have also been identified as important factors pertaining to the construct of threat (Barlow, Reference Barlow2004; McFall & Wollersheim, Reference McFall and Wollersheim1979).
The majority of research investigating overestimation of threat has been conducted using self-report questionnaires. Several studies have found that beliefs about threat are elevated in OCD patients compared to normal controls (Exner, Zetsche, Lincoln, & Rief, Reference Exner, Zetsche, Lincoln and Rief2014; Freeston et al., Reference Freeston, Ladouceur, Gagnon and Thibodeau1993; Mavrogiorgou et al., Reference Mavrogiorgou, Bethge, Luksnat, Nalato, Juckel and Brüne2016; OCCWG, 2001, 2003; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Steketee et al., Reference Steketee, Frost and Cohen1998; Tolin et al., Reference Tolin, Worhunsky and Maltby2006). For example, Exner et al. (Reference Exner, Zetsche, Lincoln and Rief2014) found that participants with OCD performed significantly more poorly on a prediction task compared to healthy controls due to heightened threat overestimations. The tendency for OCD patients to underestimate their coping ability has also been explored, with poorer estimates of coping being predictive of more severe OCD (Woods et al., Reference Woods, Frost and Steketee2002). Threat estimation beliefs have also been shown to correlate with OC symptoms in OCD samples (OCCWG, 2003; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Steketee et al., Reference Steketee, Frost and Cohen1998). These associations are also evident in studies utilising non-clinical samples showing a link between threat estimation and OC symptoms (Freeston et al., Reference Freeston, Ladouceur, Gagnon and Thibodeau1993; Moulding et al., Reference Moulding, Anglim, Nedeljkovic, Doron, Kyrios and Ayalon2010; Myers et al., Reference Myers, Fisher and Wells2008; Parrish & Radomsky, Reference Parrish and Radomsky2011; Tolin et al., Reference Tolin, Abramowitz, Brigidi and Foa2003). For example, Tolin et al. (Reference Tolin, Abramowitz, Brigidi and Foa2003) found that threat estimation significantly predicted OC symptoms in a non-clinical sample, including checking, hoarding, neutralising, obsessions, and washing. Similarly, Parrish and Radomsky (Reference Parrish and Radomsky2011) found that increases in perceived threat were associated with increased anxiety and compulsive urges in a series of experimental vignettes.
When comparing OCD patients and patients with other anxiety disorders on threat estimation beliefs, some studies report significant differences (OCCWG, 2001; Steketee et al., Reference Steketee, Frost and Cohen1998; Tolin et al., Reference Tolin, Worhunsky and Maltby2006). For example, the original validation studies of the Obsessive Beliefs Questionnaire found that OCD patients scored higher on threat estimation compared to anxious control participants (OCCWG, 2001). Similarly, Tolin et al. (Reference Tolin, Worhunsky and Maltby2006) found that OCD patients held stronger beliefs about threat estimation compared to anxious controls, although this did not hold after controlling for depression and trait anxiety. Other results suggest that threat estimation may not be specific to OCD, but instead may be characteristic of anxiety disorders in general (OCCWG, 2003; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Tolin et al., Reference Tolin, Abramowitz, Brigidi and Foa2003). For example, Tolin et al. (Reference Tolin, Abramowitz, Brigidi and Foa2003) found that in addition to significantly predicting OC symptoms, threat estimation showed a significant relationship with non-OCD psychopathology (e.g., social anxiety, depression).
Within the relevant literature, some research supports the idea that adults with OCD perceive threatening information with enhanced perceptions of probability and severity for harm occurring, as well as enhanced personal vulnerability and ‘looming’ vulnerability (belief that a dreaded threat is rapidly approaching). For example, one study found that while participants with subclinical OCD perceived higher probability of contamination, more imminent contamination, and lack of control over contamination compared to control participants, looming vulnerability was the only variable that independently contributed to OC symptoms (Riskind, Abreu, Strauss, & Holt, Reference Riskind, Abreu, Strauss and Holt1997). Results vary in other studies; for example, in a study assessing differences in threat estimations between OCD patients and students, increased severity estimation and decreased coping ability were correlated with OC symptoms for both groups, whereas probability estimation was only associated with OC symptoms in the student sample (Woods et al., Reference Woods, Frost and Steketee2002). The need to determine which components of threat estimation are most problematic in OCD has been pointed out (e.g., personal versus general incidence probability). To this end, studies have found that individuals with OCD overestimate the likelihood of harm occurring to them and experience less relief than individuals without OCD when given factual information about the unlikely occurrence of dangerous events, leading some authors to conclude that OCD patients overestimate their personal vulnerability rather than having a knowledge deficit relating to overestimations of overall probability of negative events (Moritz & Jelinek, Reference Moritz and Jelinek2009; Moritz & Pohl, Reference Moritz and Pohl2009; Niemeyer et al., Reference Niemeyer, Moritz and Pietrowsky2013).
In terms of experimental studies, there is a lack of research examining the role of threat biases in OCD. Perhaps the most relevant research is that of Jones and Menzies (Reference Jones and Menzies1997a) who explored the relationship between threat cognitions (among others) and overt displays of OCD washing behaviours during a behavioural avoidance test. Results found that of the cognitive domains assessed, danger expectancies were the most likely mediator of OCD washing behaviours, showing a ‘strong, reliable and robust’ relationship with both covert (i.e., urge to wash, distress) and overt (i.e., avoidance, washing) OC symptoms. The authors concluded that substantial support had been found for threat-based models of OCD, and failed to support models emphasising responsibility and perfectionism. These results were further supported by a more recent experimental study with non-clinical participants, which found that danger expectancy concerning severity of disease almost entirely mediated the relationship between disgust sensitivity and washing time (Thorpe, Barnett, Friend, & Nottingham, Reference Thorpe, Barnett, Friend and Nottingham2011). Such studies suggest an important role of threat as a maintaining factor in OCD symptoms, with potentially greater impact than that of responsibility. The role of threat was also evident in a recent systematic review on responsibility manipulations, which found a significant effect of the ‘responsibility’ manipulations on threat ratings of probability and severity of harm in the majority of studies (Mantz & Abbott, Reference Mantz and Abbott2017). Further, a number of variables (e.g., checking, hesitations) showed a similar or pronounced effect for conditions targeting responsibility combined with threat (Ladouceur et al., Reference Ladouceur, Rhéaume and Aublet1997; Mancini et al., Reference Mancini, D'Olimpio and Cieri2004), while others only reached significance (e.g., doubt, modifications) when threat was included in the manipulation (Ladouceur et al., Reference Ladouceur, Rhéaume and Aublet1997). The authors thus concluded that threat appraisals are a likely contributor to OCD symptomatology and recommended that further experimental studies manipulating danger expectancies be undertaken to better understand the role of this belief domain on OCD phenomena.
Perfectionism and intolerance of uncertainty
Defined by the OCCWG (2001, p. 1004), perfectionism refers to ‘the belief that there is a perfect solution to every problem, that doing something perfectly is possible and necessary, and that even minor mistakes will have serious consequences’. The idea that perfectionism works as a cognitive mediator of OCD symptomatology has been given substantial consideration in the literature (Frost, Novara, & Rhéaume, Reference Frost, Novara, Rhéaume, Frost and Steketee2002; Guidano, Liotti, & Guidano, Reference Guidano, Liotti and Guidano1983; Mallinger, Reference Mallinger1984; McFall & Wollersheim, Reference McFall and Wollersheim1979; OCCWG, 1997; Pacht, Reference Pacht1984; Rasmussen & Eisen, Reference Rasmussen and Eisen1989). This notion is based on the idea that perfectionistic individuals struggle to tolerate mistakes or imperfection, and as such, set unrealistic performance standards whereby they attempt to uphold perfect conditions and evade feelings of failure (Frost & Steketee, Reference Frost and Steketee1997; Jones & Menzies, Reference Jones and Menzies1997a). For example, the OCD sufferer may need to fill out a form ‘perfectly’ or repeat a routine action until it feels ‘just right’ (Leckman, Walker, Goodman, Pauls, & Cohen, Reference Leckman, Walker, Goodman, Pauls and Cohen1994). The OCCWG (1997) suggest that perfectionism often works in conjunction with intolerance of uncertainty (IU), whereby perfectionistic behaviours aim to increase certainty about future outcomes. IU refers to ‘beliefs about the necessity for being certain, that one has poor capacity to cope with unpredictable change, and that it is difficult to function adequately in ambiguous situations’ (OCCWG, 2001, p. 1004). While previous research suggests that IU might be more specific to worry and generalised anxiety disorder (GAD) than other anxiety disorders (Dugas, Buhr, & Ladouceur, Reference Dugas, Buhr, Ladouceur, Heimberg, Turk and Mennin2004), researchers have also contended that a low tolerance for uncertainty or ambiguity may be a central component in OCD symptomatology (Carr, Reference Carr1974; Rasmussen & Eisen, Reference Rasmussen and Eisen1989), whereby uncertainty is experienced as upsetting and stressful, leading to compulsions that work to eliminate uncertainty and reduce distress (Holaway, Heimberg, & Coles, Reference Holaway, Heimberg and Coles2006; Sarawgi, Oglesby, & Cougle, Reference Sarawgi, Oglesby and Cougle2013; Tolin, Abramowitz, Brigidi, & Foa, Reference Tolin, Abramowitz, Brigidi and Foa2003).
As with the belief domains already reviewed, results pertaining to perfectionism appear mixed and experimental studies are scarce. Studies report that individuals with OCD have increased perfectionism scores in comparison to non-clinical controls (Frost & Steketee, Reference Frost and Steketee1997; OCCWG, 2001, 2003; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Tolin et al., Reference Tolin, Worhunsky and Maltby2006). Perfectionism beliefs have also been shown to correlate with OC symptoms (Ferrari, Reference Ferrari1995; Frost, Steketee, Cohn, & Griess, Reference Frost, Steketee, Cohn and Griess1994; Myers et al., Reference Myers, Fisher and Wells2008; OCCWG, 2003; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Tolin et al., Reference Tolin, Abramowitz, Brigidi and Foa2003), even after controlling for responsibility and responsibility/threat beliefs (Rhéaume et al., Reference Rhéaume, Freeston, Dugas, Letarte and Ladouceur1995; Wu & Cortesi, Reference Wu and Cortesi2009). This has led authors to conclude that perfectionism might play an important yet underestimated role in OCD and that cognitive models allocating a central role to responsibility are only partially supported. Results, however, are mixed as to whether perfectionism beliefs differ between OCD and other anxiety disorders, with some studies suggesting that perfectionism is specific to OCD (Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004), while others report no differences between participant groups (Frost & Steketee, Reference Frost and Steketee1997; OCCWG, 2003) or differences that fail to hold after controlling for depression and trait anxiety (Tolin et al., Reference Tolin, Worhunsky and Maltby2006). It has also been suggested that perfectionism may partially mediate the relationship between responsibility and OCD symptoms (Bouchard, Rhéaume, & Ladouceur, Reference Bouchard, Rhéaume and Ladouceur1999; Pleva & Wade, Reference Pleva and Wade2006). In terms of OCD symptom subtypes, perfectionism beliefs have been linked with symmetry, ordering, and arranging symptoms (Myers et al., Reference Myers, Fisher and Wells2008; Summerfeldt, Reference Summerfeldt2004; Tolin et al., Reference Tolin, Abramowitz, Brigidi and Foa2003). Other, studies have reported a link between maladaptive perfectionism domains (e.g., concern over mistakes, doubts about actions), not just right experiences (feelings of incompleteness, conceptually related to perfectionism) and OC symptoms, including checking, ordering, and doubting (Coles, Frost, Heimberg, & Rhéaume, Reference Coles, Frost, Heimberg and Rhéaume2003; Fitch & Cougle, Reference Fitch and Cougle2013; Moretz & McKay, Reference Moretz and McKay2009).
As with the other belief domains, research on IU in adults is largely correlational. Studies report that individuals with OCD have increased IU scores in comparison to non-clinical controls (Freeston et al., Reference Freeston, Ladouceur, Gagnon and Thibodeau1993; Holaway et al., Reference Holaway, Heimberg and Coles2006; OCCWG, 2001, 2003; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Steketee et al., Reference Steketee, Frost and Cohen1998; Tolin et al., Reference Tolin, Worhunsky and Maltby2006). For example, Tolin et al. (Reference Tolin, Abramowitz, Brigidi and Foa2003) found that IU was greatest for OCD participants with compulsive checking compared to both non-checking OCD patients and non-anxious controls, who did not differ from each other. IU beliefs have also been shown to correlate with OC symptoms in clinical and non-clinical samples (Boelen & Reijntjes, Reference Boelen and Reijntjes2009; Calleo, Hart, Björgvinsson, & Stanley, Reference Calleo, Hart, Björgvinsson and Stanley2010; Dugas, Gosselin, & Ladouceur, Reference Dugas, Gosselin and Ladouceur2001; Fergus & Wu, Reference Fergus and Wu2010; Freeston et al., Reference Freeston, Ladouceur, Gagnon and Thibodeau1993; Holaway et al., Reference Holaway, Heimberg and Coles2006; OCCWG, 2003; Sarawgi et al., Reference Sarawgi, Oglesby and Cougle2013; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Sookman & Pinard, Reference Sookman, Pinard, Frost and Steketee2002; Steketee et al., Reference Steketee, Frost and Cohen1998). For example, Steketee et al. (Reference Steketee, Frost and Cohen1998) and Fergus and Wu (Reference Fergus and Wu2010) found that IU predicted OC symptoms beyond other belief domains (e.g., responsibility, threat estimation) after controlling for general distress. Further, Lind and Boschen (Reference Lind and Boschen2009) found that while both responsibility and IU belief domains were correlated with the incidence of compulsive checking in a mixed sample, the relationship between responsibility and checking was completely mediated by IU. More recently, Sarawgi et al. (Reference Sarawgi, Oglesby and Cougle2013) found that IU uniquely predicted OC symptoms, including ordering and arranging, checking, contamination fear, and obsession symptoms. This relationship held after controlling for depression and anxiety. Results are not always so consistent; for example, Tolin et al. (Reference Tolin, Abramowitz, Brigidi and Foa2003) found that tolerance for uncertainty failed to predict any OC subscales.
A substantial amount of research has investigated IU beliefs in both OCD and GAD samples. Some studies report significant differences (Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Steketee et al., Reference Steketee, Frost and Cohen1998), while others do not (Gentes & Ruscio, Reference Gentes and Ruscio2011; OCCWG, 2003). For example, Dugas et al. (Reference Dugas, Gosselin and Ladouceur2001) found that IU has a stronger role in GAD while Sica et al. (Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004) found that IU was one of two belief domains that best differentiated between OCD, GAD, and control samples, with stronger IU beliefs in OCD compared to the other groups. Other studies have found similar levels of IU in both GAD and OCD (Fergus & Wu, Reference Fergus and Wu2010; Holaway et al., Reference Holaway, Heimberg and Coles2006). In line with this, a meta-analysis assessing IU in GAD, OCD, and major depressive disorder (MDD) found that IU was significantly related to symptoms of each disorder and did not demonstrate narrow specificity (Gentes & Ruscio, Reference Gentes and Ruscio2011).
As with the other belief domains, experimental studies investigating the role of IU in producing compulsive behaviours are lacking. In one study, IU and perfectionism beliefs were the only significant predictor of urge to check and post-task anxiety, although the independent role of IU could not be assessed due to the use of a combined measure (Fitch & Cougle, Reference Fitch and Cougle2013). Further, a recent study incorporating OC-related in vivo tasks (e.g., stove checking, hand immersion in a contaminant) found that IU uniquely predicted greater anxiety and urge to check/wash, lower behavioural approach, washing duration and higher clutter-related distress, urge to straighten, and ordering and arranging duration (Sarawgi et al., Reference Sarawgi, Oglesby and Cougle2013). Experimental studies have also investigated repeated checking and its relationship to memory confidence and uncertainty in OCD. For example, it has been found that when healthy individuals engage in OCD-like repeated checking, confidence in memories related to the checking decreases (Ashbaugh & Radomsky, Reference Ashbaugh and Radomsky2007; Coles, Radomsky, & Horng, Reference Coles, Radomsky and Horng2006; van den Hout & Kindt, Reference van den Hout and Kindt2003) and uncertainty and doubt increases (van den Hout & Kindt, Reference van den Hout and Kindt2003). This counterproductive effect proves difficult for OCD sufferers who likely engage in compulsions, particularly checking, in an attempt to alleviate uncertainty related to obsessive beliefs (Tolin et al., Reference Tolin, Abramowitz, Brigidi, Amir, Street and Foa2001; van den Hout & Kindt, Reference van den Hout and Kindt2003).
Overimportance of thoughts and need to control thoughts
Overimportance of thoughts (OT) refers to ‘the belief that the mere presence of a thought indicates that it is important’ (OCCWG, 2001, p. 1003). Individuals with OCD often believe that merely having a thought implies that it is important or reflects their true desires (OCCWG, 1997; Rheaume, Ladouceur, & Freeston, Reference Rhéaume, Ladouceur and Freeston1997; Thordarson & Shafran, Reference Thordarson, Shafran, Frost and Steketee2002). This cognitive process has been linked with both thought-action fusion and magical thinking, of which the beliefs may reflect either (OCCWG, 2001). Thought-action fusion, for example, refers to the belief that thoughts are able to affect the external world (e.g., I am more likely to have a car accident if I think about it) or that thinking about doing something is morally equivalent to actually doing it (e.g., committing adultery) (Amir, Freshman, Ramsey, Neary, & Brigidi, Reference Amir, Freshman, Ramsey, Neary and Brigidi2001; Shafran et al., Reference Shafran, Thordarson and Rachman1996). Given this appraisal of intrusive thoughts being important and potentially harmful, the presence of such thoughts is viewed negatively and likely leads to a need to resist or control one's thoughts (Clark & Purdon, Reference Clark and Purdon1993; OCCWG, 1997). The need to control thoughts (NCT) refers to ‘the belief that it is important, possible, and desirable to exert complete control over intrusive thoughts, images, and impulses’ (OCCWG, 2001, p. 1003). Theorists have asserted that individuals with OCD believe it is necessary and possible to control one's thoughts and will often make attempts to control their thoughts through means such as thought suppression (Abramowitz, Whiteside, Kalsy, & Tolin, Reference Abramowitz, Whiteside, Kalsy and Tolin2003; Clark & Purdon, Reference Clark and Purdon1993; Moulding & Kyrios, Reference Moulding and Kyrios2006; Purdon & Clark, Reference Purdon, Clark, Frost and Steketee2002). However, individuals with OCD typically struggle to control their thoughts (Tolin, Abramowitz, Przeworski, & Foa, Reference Tolin, Abramowitz, Przeworski and Foa2002; Tolin, Hamlin, & Foa, Reference Tolin, Hamlin and Foa2002), thus resulting in enhanced anxiety and negative judgements (Tolin, Abramowitz, Hamlin, Foa, & Synodi, Reference Tolin, Abramowitz, Hamlin, Foa and Synodi2002).
As with the belief domains already reviewed, results pertaining to OT and NCT lack consistency, and experimental studies are limited. Studies have found that OT and/or NCT are elevated in individuals with OCD compared to non-clinical samples (Kumar et al., Reference Kumar, Sharma, Kandavel and Reddy2012; Mavrogiorgou et al., Reference Mavrogiorgou, Bethge, Luksnat, Nalato, Juckel and Brüne2016; OCCWG, 2001, 2003; Pazvantoğlu et al., Reference Pazvantoğlu, Algül, Ateş, Sarısoy, Ebrinc, Başoğlu and Cetin2013; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Tolin et al., Reference Tolin, Worhunsky and Maltby2006) and correlate with measures of OC symptoms (Cucchi et al., Reference Cucchi, Bottelli, Cavadini, Ricci, Conca, Ronchi and Smeraldi2012; Emmelkamp & Aardema, Reference Emmelkamp and Aardema1999; Gwilliam et al., Reference Gwilliam, Wells and Cartwright‐Hatton2004; Myers & Wells, Reference Myers and Wells2005; OCCWG, 2003; Tolin et al., Reference Tolin, Abramowitz, Brigidi and Foa2003). For example, Tolin et al. (Reference Tolin, Abramowitz, Brigidi and Foa2003) found that OT significantly predicted OC neutralising symptoms, and NCT significantly predicted OC obsessing symptoms in a non-clinical sample. In more recent studies, Cucchi et al. (Reference Cucchi, Bottelli, Cavadini, Ricci, Conca, Ronchi and Smeraldi2012) and Pazvantoglu et al. (Reference Pazvantoğlu, Algül, Ateş, Sarısoy, Ebrinc, Başoğlu and Cetin2013) found that beliefs about the uncontrollability and danger of thoughts and NCT were positively correlated with degree of doubt/indecisiveness in OCD patients. However, such results are not found consistently; for example, Sica et al. (Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004) found that OT and NCT were not significantly correlated with OC symptoms in an OCD sample.
When compared to other clinical groups, studies suggest that OT and/or NCT are more strongly endorsed by OCD patients compared to individuals with other anxiety disorders and/or depression (Morillo et al., Reference Morillo, Belloch and García-Soriano2007; OCCWG, 2003; Sica et al., Reference Sica, Coradeschi, Sanavio, Dorz, Manchisi and Novara2004; Tolin et al., Reference Tolin, Worhunsky and Maltby2006). For example, Morillo et al. (Reference Morillo, Belloch and García-Soriano2007) found that worries about thoughts coming true and the importance of controlling thoughts were specific to OCD patients when compared with depressed patients, anxious control patients, and non-clinical participants. Other results suggest that OT and NCT may be OCD-relevant but not OCD-specific. For example, Cucchi et al. (Reference Cucchi, Bottelli, Cavadini, Ricci, Conca, Ronchi and Smeraldi2012) found that NCT beliefs did not differ between OCD patients and those with panic disorder, although both scored significantly higher than healthy control participants. More recently, McKay et al. (Reference McKay, Kim, Taylor, Abramowitz, Tolin, Coles and Olatunji2014) conducted a large study comparing individuals with OCD, other anxiety disorders, and undergraduate students and found that while responsibility beliefs were prominent in all three groups, NCT was the only subscale unique to OCD, although it was unexpectedly lower than the other groups. Similarly, Tolin et al. (Reference Tolin, Worhunsky and Maltby2006) found that of the six belief domains, only NCT was able to differentiate between OCD and other anxiety disordered patients. It has thus been suggested that beliefs about controlling one's thoughts may have the clearest relationship with OCD compared to other anxiety disorders (McKay et al., Reference McKay, Kim, Taylor, Abramowitz, Tolin, Coles and Olatunji2014).
Cognitive Models of OCD in Children and Adolescents
It has been suggested that cognitive models of OCD developed with adult populations may also be useful in understanding and treating the disorder in children and adolescents with OCD. To evaluate this claim, a systematic review was conducted examining the applicability of the cognitive model of OCD to children and adolescents (Reynolds & Reeves, Reference Reynolds and Reeves2008). Specifically, this review assessed cognitive models of responsibility, thought-action fusion, and meta-cognition. After reviewing the 11 studies meeting criteria for inclusion, it was found that the majority of studies provided support for the use of adult cognitive models of OCD in childhood and adolescence. For example, Farrell and Barrett (Reference Farrell and Barrett2006) showed that cognitions observed in adults with OCD are also characteristic of children and adolescents with the disorder. As such, the authors concluded that cognitive models of OCD do apply to children and adolescents (Reynolds & Reeves, Reference Reynolds and Reeves2008). This finding is in line with the similarities between adults and children in the presentation of OCD, and validates the use of adult OCD cognitive treatments with young people (Reynolds & Reeves, Reference Reynolds and Reeves2008). Although this review was limited by its focus on inflated responsibility, thought-action fusion and metacognitions, it provides preliminary evidence in support of the application of adult models of OCD to child and adolescent samples. Authors recommended that future research include experimental studies using clinical groups, as this was lacking in the review.
Research Examining Obsessive Belief Domains in Children and Adolescents
Inflated responsibility
Research assessing the role of responsibility in OCD among children and adolescents is sparse and based largely on observational studies, preventing a causative relationship from being established. For example, Magnúsdóttir and Smári (Reference Magnúsdóttir and Smári2004) investigated the correlation between responsibility attitudes and OC symptoms in a sample of non-clinical children and found that responsibility attitudes added significantly to the prediction of obsessive symptoms. Similarly, Matthews, Reynolds, and Derisley (Reference Matthews, Reynolds and Derisley2007) found that inflated responsibility beliefs were a significant independent predictor of OC symptoms in non-clinical adolescents, although when comparing cognitive appraisals in children with OCD, anxious children, and non-clinical controls, Barrett and Healy (Reference Barrett and Healy2003) found that children with OCD reported significantly higher ratings of responsibility than non-clinical, but not anxious children. In contrast, Libby, Reynolds, Derisley, and Clark (Reference Libby, Reynolds, Derisley and Clark2004) found that young people with OCD had significantly higher scores on inflated responsibility and thought-action fusion compared to young people with an anxiety disorder or no diagnosis. However, inflated responsibility was the only significant predictor of OC symptoms. Research also suggests that responsibility appraisals may be have an impact developmentally, given findings that children with OCD report significantly less inflated responsibility appraisals than adolescents and adults with OCD who do not differ from each other (Farrell & Barrett, Reference Farrell and Barrett2006; Pişgin & Özen, Reference Pişgin and Özen2010). Similarly, Farrell, Waters, and Zimmer-Gembeck (Reference Farrell, Waters and Zimmer-Gembeck2012) found that responsibility and metacognition were associated with OCD severity for adolescents but not for children. Interestingly, Lawrence and Williams (Reference Lawrence and Williams2011) found that adolescents with a history of OCD reported increased responsibility for significant negative incidents prior to OCD onset compared to adolescents with no history of OCD. Authors thus concluded that an inflated sense of responsibility, combined with particular events, may contribute to the development of OCD. To assess the role of responsibility in OCD further, a recent meta-analysis was conducted and found inconclusive support for the specificity of responsibility to OCD (Pozza & Detore, Reference Pozza and Dèttore2014a). Authors also reported that responsibility was more strongly related to OCD symptoms in adult than in child or adolescent samples, and recommended further research with experimental designs to better ascertain the role of responsibility beliefs in OCD symptom changes (Pozza & Dèttore, Reference Pozza and Dèttore2014a).
In terms of experimental research with an in vivo manipulation designed to manipulate levels of responsibility, only two studies have been conducted to investigate the role of inflated responsibility on OCD symptoms with a paediatric sample (i.e., Barrett & Healy-Farrell, Reference Barrett and Healy-Farrell2003; Reeves, Reynolds, Coker, & Wilson, Reference Reeves, Reynolds, Coker and Wilson2010). Results were mixed; for example, both studies found that ratings of perceived responsibility were significantly greater in the high compared to moderate and low responsibility conditions, thus supporting an impact of the experimental manipulation on responsibility. However, only one study found a significant increase in OCD-related behaviours (e.g., neutralising, hesitations, overall time taken) for the high compared to the low responsibility condition (Reeves et al., Reference Reeves, Reynolds, Coker and Wilson2010), while the other found no effect of inflated responsibility on avoidance behaviours or ritualising (Barrett & Healy-Farrell, Reference Barrett and Healy-Farrell2003). Based on the latter study, the authors concluded that inflated responsibility may not be an important cognitive process in childhood OCD (Barrett & Healy-Farrell, Reference Barrett and Healy-Farrell2003). Similarly, a more recent study on young people with OCD using an experimental cognitive appraisal task with vignettes to manipulate perceived responsibility found that responsibility was not related to urge to check. Authors concluded that responsibility biases may not be central to childhood OCD (Farrell, Waters, Boschen, & Milliner, Reference Farrell, Waters, Boschen and Milliner2011). Thus, the role of responsibility in child and adolescent OCD requires further investigation.
Overestimation of threat
A number of studies have assessed threat cognitions among anxious children, with studies showing that clinically anxious children interpret ambiguous scenarios to be more threatening than non-clinical children (e.g., Barrett, Rapee, Dadds, & Ryan, Reference Barrett, Rapee, Dadds and Ryan1996; Bögels & Zigterman, Reference Bögels and Zigterman2000; Creswell, Schniering, & Rapee, Reference Creswell, Schniering and Rapee2005; Muris, Rapee, Meesters, Schouten, & Geers, Reference Muris, Rapee, Meesters, Schouten and Geers2003; Suarez & Bell-Dolan, Reference Suarez and Bell-Dolan2001; Waters, Craske, Bergman, & Treanor, Reference Waters, Craske, Bergman and Treanor2008). In terms of young people with OCD, there is relatively less research examining threat cognitions in comparison to other belief domains. This was evident in a systematic review of cognitive processes in paediatric OCD, which gave little consideration to cognitions other than responsibility, thought-action fusion, and metacognitions (Reynolds & Reeves, Reference Reynolds and Reeves2008). Of these, some studies have reported a significant difference between OCD patients and normal controls. For example, when compared with other groups, Barrett and Healy (Reference Barrett and Healy2003) found that children with OCD reported higher severity, but not probability, of threat in comparison to non-clinical controls, although there was not a clear differentiation between OCD and anxious children. Similarly, Farrell, Hourigan, Waters, and Harrington (Reference Farrell, Hourigan, Waters and Harrington2015) found that children with OCD perceived ambiguous scenarios as being more difficult to manage compared to non-clinical children, although these differences did not hold after self-reported anxiety symptoms were controlled, suggesting that interpretation biases may be more closely related to anxiety symptoms than OCD. Further, cognitive responses concerning threat-based thoughts did not show an inflated threat interpretation bias, inconsistent with paediatric anxiety research showing enhanced threat-based thinking (e.g., Creswell et al., Reference Creswell, Schniering and Rapee2005; Waters et al., Reference Waters, Craske, Bergman and Treanor2008). The authors suggested that this may be related to the developmental stage of the included sample, or that threat cognitions and coping appraisals may be specific to OCD-related situations. In line with this, some studies suggest that threat estimations may be affected developmentally, with less prominence in children compared to adults (Pişgin & Özen, Reference Pişgin and Özen2010). For example, one study found that children with OCD showed lower probability of threat (but similar perceived severity of harm) compared to adolescents and adults with OCD (Farrell & Barrett, Reference Farrell and Barrett2006). Another study found that negative cognitions concerning physical threat, social threat, and personal failure were related to severity of obsessions, but not compulsions, in OCD adolescents aged 13–18 (Verhaak & De Haan, Reference Verhaak and De Haan2007). However, no significant correlations were found for a group of OCD children aged 8–12 years, supporting a developmental difference in the belief domains (Verhaak & De Haan, Reference Verhaak and De Haan2007). Authors have thus recommended that cognitive models of OCD consider developmental differences in the cognitive processing of threat, and further examine the occurrence and nature of these biases in children, adolescents and adults (Farrell & Barrett, Reference Farrell and Barrett2006; Farrell et al., Reference Farrell, Hourigan, Waters and Harrington2015).
When considering experimental studies examining overestimation of threat in children and adolescents, research is scarce and inconclusive. Two experimental studies measuring probability and severity of harm during a ‘responsibility’ manipulation were identified in a recent systematic review (Mantz & Abbott, Reference Mantz and Abbott2017). One study reported no significant difference for probability or severity between responsibility conditions in an OCD sample (Barrett & Healy-Farrell, Reference Barrett and Healy-Farrell2003), while the other study failed to report results pertaining to threat appraisals (Reeves et al., Reference Reeves, Reynolds, Coker and Wilson2010). Further experimental studies are thus warranted to better ascertain the role of threat cognitions in the onset and maintenance of paediatric OCD. This will ultimately prove useful in determining therapeutic targets requiring emphasis in treatment.
Perfectionism and intolerance of uncertainty (IU)
Although limited in number, some research support is evident for the role of these belief domains in child and adolescent OCD. One study found that young people with OCD had significantly higher ratings of perfectionism beliefs (i.e., concern over mistakes) compared to both anxious and non-clinical controls (Libby et al., Reference Libby, Reynolds, Derisley and Clark2004). A more recent study, however, found that perfectionism and certainty beliefs in an unselected sample of adolescents were similar to levels found in previous studies of young people with an OCD diagnosis (Coles, Ravid, Franklin, Storch, & Khanna, Reference Coles, Ravid, Franklin, Storch and Khanna2014). Perfectionism beliefs have also been shown to correlate with OC symptoms (Coles et al., Reference Coles, Ravid, Franklin, Storch and Khanna2014; Huan, Rice, & Storch, Reference Huan, Rice and Storch2008; Soreni et al., Reference Soreni, Streiner, McCabe, Bullard, Swinson, Greco and Szatmari2014). For instance, Soreni et al. (Reference Soreni, Streiner, McCabe, Bullard, Swinson, Greco and Szatmari2014) found that perfectionism beliefs were associated with severity of OCD and depressive symptoms in children and adolescents with OCD. In terms of development, it has been suggested that perfectionism and IU beliefs are not limited to adulthood but also observed during childhood and adolescence (Pişgin & Özen, Reference Pişgin and Özen2010).
Overimportance of thoughts and need to control thoughts
Studies have found that young people with OCD have significantly higher ratings of thought-action fusion beliefs and less cognitive control compared to anxious and/or non-clinical controls (Barrett & Healy, Reference Barrett and Healy2003; Kadak, Balsak, Besiroglu, & Çelik, Reference Kadak, Balsak, Besiroglu and Çelik2014; Libby et al., Reference Libby, Reynolds, Derisley and Clark2004). Beliefs related to OT (i.e., thought-action fusion, magical thinking) have also been shown to correlate with OC symptoms in non-clinical samples (Bolton, Dearsley, Madronal‐Luque, & Baron‐Cohen, Reference Bolton, Dearsley, Madronal‐Luque and Baron‐Cohen2002; Evans, Milanak, Medeiros, & Ross, Reference Evans, Milanak, Medeiros and Ross2002; Matthews et al., Reference Matthews, Reynolds and Derisley2007; Muris, Meesters, Rassin, Merckelbach, & Campbell, Reference Muris, Meesters, Rassin, Merckelbach and Campbell2001). For example, Evans et al. (Reference Evans, Milanak, Medeiros and Ross2002) found that magical thinking beliefs were significantly correlated with rituals and compulsive behaviours in non-clinical children. However, Farrell et al. (Reference Farrell, Waters and Zimmer-Gembeck2012) and Verhaak and De Haan (Reference Verhaak and De Haan2007) found no significant relationship between magical thinking/thought-action fusion beliefs and OCD severity in a sample of children and adolescents with OCD, although thought suppression and metacognition (including NCT beliefs, among others) were strongly correlated with OCD severity in adolescents (Farrell et al., Reference Farrell, Waters and Zimmer-Gembeck2012), indicating the need for further research on these constructs. In terms of development, it has been suggested that OCD-type cognitions related to overimportance of thoughts (Pişgin & Özen, Reference Pişgin and Özen2010), thought-action fusion, and controllability of thoughts are comparable across age groups (Farrell & Barrett, Reference Farrell and Barrett2006), although concerns about controlling one's thoughts may be more pronounced in adulthood (Pişgin & Özen, Reference Pişgin and Özen2010).
Limitations in Research on OCD Belief Domains
OCD is a debilitating and prevalent disorder associated with a range of impairments in everyday functioning. The appraisal model asserts that OCD occurs as a result of interpreting intrusive thoughts in a particular way. To confirm this premise, it was suggested that individuals with OCD should show stronger endorsement of the obsessive belief domains than non-clinical persons and individuals with other anxiety disorders (Tolin et al., Reference Tolin, Worhunsky and Maltby2006). Further, to determine a causal role of these belief domains in the development of compulsive behaviours, a clear relationship between obsessive beliefs and behavioural symptoms needs to be demonstrated (Tolin et al., Reference Tolin, Worhunsky and Maltby2006). This appears particularly important given that treatment of the disorder often involves consideration of the cognitive domains impacting OC symptoms.
After reviewing research pertaining to the six identified belief domains, limitations are evident. First, literature on the OCD belief domains is dominated by correlational studies reliant on self-report questionnaires, which prevents understanding of the causal relationship between belief domains and OC symptoms (Julien et al., Reference Julien, O'Connor and Aardema2007; Mantz & Abbott, Reference Mantz and Abbott2017). This proves problematic for relevant cognitive models in asserting that the belief domains are specific and pivotal factors in the development and expansion of obsessive-compulsive behaviours in OCD patients. Further issues are apparent when looking at self-report questionnaires, namely: (1) studies employ varying self-report instruments when investigating the relationship between belief domains and OC symptoms, which may contribute to inconsistencies among results (Brakoulias et al., Reference Brakoulias, Starcevic, Berle, Milicevic, Hannan and Martin2014); and (2) the revised primary measure of cognitive appraisals (Obsessive Beliefs Questionnaire) does not allow researchers to discriminate between certain belief domains (e.g., responsibility and threat). This makes it difficult to determine which belief domain(s) are most critical in the development and maintenance of OC symptoms. Second, when examining such studies it appears that results are mixed, with inconclusive findings as to whether individuals with OCD endorse the belief domains more strongly than non-clinical and anxious persons, similar to results reported by Julien et al. (Reference Julien, O'Connor and Aardema2007). Such findings are concerning for the appraisal model, which is based on the premise that dysfunctional belief domains are central to OCD.
When considering the extant literature involving experimental studies, these are scarce and results are inconclusive. Few experimental studies employ objective behavioural measures to determine the impacts of the cognitive domains on OCD symptoms. For example, a number of experimental studies utilise vignettes reliant on self-report, thus limiting conclusions. While some experimental studies with clinical samples support a causal role of appraisals in producing compulsive behaviours (e.g., Arntz et al., Reference Arntz, Voncken and Goosen2007; Lopatka & Rachman, Reference Lopatka and Rachman1995), results overall are mixed, preventing strong conclusions regarding the role of belief domains in OCD symptoms. In addition, the majority of experimental studies have been conducted with non-clinical populations (e.g., Bouchard et al., Reference Bouchard, Rhéaume and Ladouceur1999; MacDonald & Davey, Reference MacDonald and Davey2005), providing limited evidence for the role of appraisals in clinical OCD samples. Another major concern within experimental studies lies in the tendency to be biased towards a particular belief domain. For instance, review of the relevant literature indicates that experimental studies mostly manipulated inflated responsibility appraisals without controlling for other cognitive domains related to OCD. This has been raised as a concern by authors who emphasise the need for experimental research to consider other belief domains (e.g., Julien et al., Reference Julien, O'Connor and Aardema2007; Mantz & Abbott, Reference Mantz and Abbott2017). For instance, a ‘responsibility’ manipulation might also have an impact on other belief domains, yet if these are not considered, authors are unable to conclude that responsibility is the sole contributor in the production of OC symptoms (Julien et al., Reference Julien, O'Connor and Aardema2007; Mantz & Abbott, Reference Mantz and Abbott2017). This is further enhanced by research findings suggesting the important role of threat (Jones & Menzies, Reference Jones and Menzies1997a; Thorpe et al., Reference Thorpe, Barnett, Friend and Nottingham2011), perfectionism (Bouchard et al., Reference Bouchard, Rhéaume and Ladouceur1999), and negative mood (MacDonald & Davey, Reference MacDonald and Davey2005) in experimental manipulations and OC behaviours.
Limitations in Child and Adolescent Research
Research with children and adolescents is limited and restricted in focus, with the majority of studies having focused on cognitive beliefs of responsibility, thought action fusion, and meta-cognition (Farrell et al., Reference Farrell, Waters and Zimmer-Gembeck2012; Reynolds & Reeves, Reference Reynolds and Reeves2008). Further, research is correlational and based on self-report measures, preventing a causal relationship between appraisals and OCD behaviours from being established. These shortcomings were supported in a recent review conducted by Reynolds and Reeves (Reference Reynolds and Reeves2008), who found that every study except one used a cross-sectional observational design. The authors thus concluded that causal relationships between cognitive processes and obsessive-compulsive symptoms could not be assumed (Reynolds & Reeves, Reference Reynolds and Reeves2008). In addition to this, the majority of studies with children and adolescents have used a non-clinical sample, posing difficulties for the generalisation of results to clinical groups with OCD (Reynolds & Reeves, Reference Reynolds and Reeves2008). When considering child and adolescent studies that have used clinical samples, findings are inconsistent and the specificity of cognitive biases to OCD is questionable, warranting further examination (Farrell et al., Reference Farrell, Waters and Zimmer-Gembeck2012). Further, experimental research is scarce, and results lack replication and are inconclusive, with some studies providing support for a causal role of appraisals in OCD behaviours (e.g., Reeves et al., Reference Reeves, Reynolds, Coker and Wilson2010) and others failing to support such a link (e.g., Barrett & Healy-Farrell, Reference Barrett and Healy-Farrell2003). As with the adult literature, it is also evident that paediatric experimental studies tend to manipulate one belief domain (e.g., inflated responsibility) without controlling for other appraisal types. Problems with cognitive questionnaires used in these studies have also been highlighted, such as the use of questionnaires designed for adult populations with unknown psychometric properties for paediatric samples (Coles et al., Reference Coles, Ravid, Franklin, Storch and Khanna2014; Verhaak & De Haan, Reference Verhaak and De Haan2007).
Areas for Future Research
Following these limitations, any reported outcomes in this area of research must be considered preliminary due to the scarcity of studies and consequent lack of replication, particularly with child and adolescent samples. As such, support for the above-mentioned premise asserting a link between appraisals and the development and maintenance of OCD symptoms is at present inconclusive. More studies with experimental designs and strong objective measures are required to clarify and expand knowledge pertaining to the role of belief domains in OCD (Mantz & Abbott, Reference Mantz and Abbott2017). Appropriate clinical samples with control groups are needed, including both anxious and non-clinical controls, to allow for adequate comparison of clinical and non-clinical groups as well as varying experimental conditions. Importantly, experimental studies need to examine and appropriately analyse other potential processes (e.g., threat) that may underlie observed behavioural changes, and avoid being biased towards a particular belief domain. This can be achieved by including a wider variety of appraisal measures to identify potential contributing cognitive variables. Without this additional empirical evidence, conclusions cannot be drawn about the relative influence of each belief domain in OCD, as well as their specificity in OCD symptom subtypes, and results emphasising one belief domain above others may be misleading. For example, Brakoulias et al. (Reference Brakoulias, Starcevic, Berle, Milicevic, Hannan and Martin2014) have emphasised the need for further research on belief domains related to contamination/cleaning symptoms and hoarding, while Fitch and Cougle (Reference Fitch and Cougle2013) have highlighted the possible understudied link between perfectionism/certainty beliefs and checking and washing symptoms. Controlling for general distress, mood, and anxiety, and considering potential mediators such as age and gender would also be beneficial (Julien et al., Reference Julien, O'Connor and Aardema2007), as well as using an adequate array of assessment, symptom, and behavioural measures.
At present, the greatest lack of research is apparent for children and adolescents with OCD. Given the application of adult cognitive models to children, combined with the importance of including age-specific cognitive aspects in treatment to engage participants and potentially improve treatment outcomes, experimental studies on younger people with OCD appear crucial to provide clarity and confidence in cognitive approaches. Further, the emergence of research indicating developmental differences in belief domains emphasises the need for additional studies with a developmental focus, perhaps exploring the developmental trajectory of beliefs associated with OCD. Overall, such research appears necessary to expand knowledge concerning hypothesised mechanisms and investigate relationships among the belief domains, as well as their causal status and explanatory power in driving OCD-related behaviours, which at present remains inconclusive.