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Surface-tension-driven evolution of a viscoplastic liquid coating the interior of a cylindrical tube

Published online by Cambridge University Press:  28 June 2022

James D. Shemilt*
Affiliation:
Department of Mathematics, University of Manchester, Manchester M13 9PL, UK
Alexander Horsley
Affiliation:
Division of Immunology, Immunity to Infection and Respiratory Medicine, University of Manchester, Manchester M13 9PL, UK
Oliver E. Jensen
Affiliation:
Department of Mathematics, University of Manchester, Manchester M13 9PL, UK
Alice B. Thompson
Affiliation:
Department of Mathematics, University of Manchester, Manchester M13 9PL, UK
Carl A. Whitfield
Affiliation:
Department of Mathematics, University of Manchester, Manchester M13 9PL, UKDivision of Immunology, Immunity to Infection and Respiratory Medicine, University of Manchester, Manchester M13 9PL, UK
*
†Email address for correspondence: james.shemilt@manchester.ac.uk

Abstract

One mechanism for airway closure in the lung is the surface-tension-driven instability of the mucus layer which lines the airway wall. We study the instability of an axisymmetric layer of viscoplastic Bingham liquid coating the interior of a rigid tube, which is a simple model for an airway that takes into account the yield stress of mucus. An evolution equation for the thickness of the liquid layer is derived using long-wave theory, from which we also derive a simpler thin-film evolution equation. In the thin-film case we show that two branches of marginally yielded static solutions of the evolution equation can be used to both predict the size of the initial perturbation required to trigger instability and quantify how increasing the capillary Bingham number (a parameter measuring yield stress relative to surface tension) reduces the final deformation of the layer. Using numerical solutions of the long-wave evolution equation, we quantify how the critical layer thickness required to form a liquid plug in the tube increases as the capillary Bingham number is increased. We discuss the significance of these findings for modelling airway closure in obstructive conditions such as cystic fibrosis, where the mucus layer is often thicker and has a higher yield stress.

Information

Type
JFM Papers
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press
Figure 0

Figure 1.Sketches of the geometry and flow structure in the long-wave model. In non-dimensionalised variables the free surface is at $r=R$ and the layer thickness is $\epsilon H$. The surface $r=\varPsi$ separates a region of shear-dominated flow near the cylinder wall and a region of plug-like flow near the free surface. We define $\varPsi \equiv \min (1,\psi )$ with $\psi$ defined in (2.13) and $\varPsi =1$ corresponding to regions of unyielded fluid. The thin-film model has qualitatively the same flow structure.

Figure 1

Figure 2.Time evolution of a thin film with $B=0.05$ and $A=0.2$. (a) Snapshots of layer height $H(z,t)$ and the internal surface $Y(z,t)$ (supplementary movie 1 is available at https://doi.org/10.1017/jfm.2022.479 for the full evolution of $H$ and $Y$ up to $t=1000$). Axial velocity, $w$, as defined in (2.26), is also shown. The plug-like region lies between $y=Y$ and $y=H$, showing significant transient deformation. (b) Time evolution of $\max _zH$ compared with the same quantity for a Newtonian ($B=0$) simulation, and time evolution of $\max _zY$ and $\max _z|\tau _w|-B$ for the $B=0.05$ simulation. (c) Example of the capillary-wave-like structures that are observed ahead of the travelling yield surface at early times, similar to those discussed in Jalaal et al. (2021). Here $Y$ and $p_z$ are shown near to the travelling yield surfaces at $t=1$. The sign changes in $p_z$ indicate reversals in the direction of flow between these structures.

Figure 2

Figure 3.Late time asymptotic solutions for $B=0.05$, compared with the final snapshot of the numerical simulation with $A=0.2$ and $B=0.05$ at $t=10^4$. (a) The static solution, $H_0$, compared with the layer height, $H(z,t=10^4)$, from the simulation. (b) Function $H_1$ compared with $Bt[H(z,t=10^4)-H_0]$ from the simulation, which represents the rate of decay of $H$ towards $H_0$. (c) Function $Y_1$ compared with $BtY(z,t=10^4)$ from the simulation, which represents the rate of decay of $Y$ towards zero.

Figure 3

Figure 4.Solutions $H_0(z;B)$ of (3.2a), (3.3) and (3.4a), which are static solutions of the evolution equation (2.27). (a) Bifurcation diagram showing $\max _zH_0$ for all values of $B$ such that solutions exist. Dotted black lines are the asymptotic approximations (3.6), (3.8) and (3.9). The arrows indicate time evolution as determined by the near-bifurcation asymptotic analysis (Appendix C). The five dots on (a) correspond to the example solutions shown in (b), at $B=0.05$, $B=0.12$ and $B=B_{*}$.

Figure 4

Figure 5.(a) Data from numerical solutions of the thin-film evolution equation at various $B$ and $A$. Each dot corresponds to a simulation with the colour indicating $\max H(z,t=1000)$. The data are linearly interpolated to produce the black contour lines, which are evenly spaced. When $A$ is small and $B$ is large, the layer is yield stabilised: no unstable growth occurs. The critical amplitude for any yielding to occur, $A_m(B)$ (dashed red), defined in (3.10), is a strict lower bound on the boundary of the yield-stabilsed region. When there is growth, the final shape either has monotonic or non-monotonic pressure, depending on $A$ and $B$. The quantity $1-H_0(z=0,B)$ (magenta) from the static solutions (figure 4) predicts the boundary of the monotonic pressure region. The maximum value of $B$ along the magenta curve is $B_*$. Two large black dots indicate the location of the example solutions shown in (b) and (c), with $H$, $70Y$ (scaled for clarity) and $p_z$ plotted at $t=1000$. Plot (b) shows a solution in the monotonic pressure region ($p_z\leq 0$) and (c) shows a solution in the non-monotonic pressure region ($p_z$ changes sign once in the domain).

Figure 5

Figure 6.(a) Snapshots of a numerical simulation with $\epsilon =0.125$, $B=0.05$ and $A=0.2$ (supplementary movie 2 is available at https://doi.org/10.1017/jfm.2022.479 for the full evolution of $H$ and $\hat {Y}$). Axial velocity, $\hat {w}$, as defined in (2.15), is also shown. (b) Time evolution of $\max _zH$, $\max _z\hat {Y}$ and $\max _z|\tilde {\tau }_w|$ for the same simulation, with plugging occurring at $t_p\approx 140$. The simulation is stopped when $\max _zH=0.7/\epsilon$ as it is clear that a plug will form. The evolution of $\max _zH$ and $\max _z|\tilde {\tau }_w|$ for a Newtonian ($B=0$) simulation with the same $\epsilon$ and $A$ shows plug formation occurring earlier, $t_p\approx 70$. (c) Snapshots of the $B=0.05$ simulation at evenly spaced time points between $t=50$ (darkest lines) and $t=130$ (lightest lines). Inset shows $\hat {Y}$ becoming equal to zero across progressively more of the domain, indicating that the small collar of fluid around $z=0$ is rigidifying. There is a small jump in $\hat {p}_z$ where $\hat {Y}$ makes contact with zero, but still $\hat{p}_z\leq 0$ everywhere.

Figure 6

Figure 7.Data from numerical solutions of the long-wave evolution equation for various values of $B$ and $\epsilon$, with $A=0.25$. Coloured dots correspond to simulations which did not plug, with the colour indicating $\max _zH(z,t=1000)$. Grey crosses correspond to simulations which are stopped early due to a plug forming. The critical thickness $\epsilon _c$ required for plug formation can be identified as the boundary of the plugging region. The plugging time, $t_{p}$, is indicated by the grey contours. The maximum $B$ for any yielding to occur, $B_m(\epsilon,0.25)$ (dashed red), provides a strict upper bound on the yield-stabilised region.

Figure 7

Figure 8.Data from numerical solutions of the long-wave evolution equation for various values of $B$ and $A$, with (a) $\epsilon =0.12$, (b) $\epsilon = 0.125$ and (c) $\epsilon =0.13$. Each dot corresponds to a solution with the colour indicating $\max _zH(z,t=1000)$. The data are interpolated linearly to produce the black contour lines, which are evenly spaced. Grey points correspond to simulations which are stopped early due to a plug forming. In (c) grey contours in the plugging region indicate the plugging time, $t_p$. The critical amplitude for any yielding to occur, $A_m(B,\epsilon )$ (dashed red), provides a strict lower bound on the boundary of the yield-stabilised region. Unlike in the thin-film case (figure 5a), the quantity $1-H_0(z=0;B,\epsilon )$ (solid magenta), where $H_0$ are the static solutions computed in Appendix E, does not provide useful information on the final shape of these layers.

Figure 8

Figure 9.(a) The functions $g_1(\varPsi )$ and $g_2(\varPsi )$ defined in (A9). (b) The functions $f_1(R,R)$ and $f_2(R,R)$ defined in (A10). All four functions are non-negative, which is used to prove that $E_{\hat {t}}\leq 0$.

Figure 9

Figure 10.(a) Solutions $\phi _1$, $\phi _2$ of the linear problem $\boldsymbol{\mathsf{L}}\boldsymbol \phi =\boldsymbol {0}$, and the solution $\phi _1^{\dagger}$ to the adjoint problem $\boldsymbol{\mathsf{L}}^{\dagger} \boldsymbol \phi ^{\dagger} =\boldsymbol {0}$. We set the amplitude of $\phi _1$ by choosing $\phi _1(L)=1$ and the amplitude of $\phi _1^{\dagger}$ by choosing $\phi _2^{\dagger} =1$, both of which are arbitrary values. (b) Solution of the evolution equation (C9), showing $\mathcal {A}$ evolving away from the fixed point at $-2.20$ towards the fixed point at $2.20$.

Figure 10

Figure 11.Approximation to the upper-branch static solution (figure 4a) with $B=10^{-3}$ using matched asymptotic expansions. (a) Composite solution, $H_c(z;10^{-3})$, which is composed of the solutions in regions I (magenta), II (black) and III (green). (b) Capillary pressure of the composite solution, $p_c\equiv -H_c-H_{c,zz}$.

Figure 11

Figure 12.Static solutions, $H_0(z;B,\epsilon )$, satisfying (E1) with monotonic curvature, for $\epsilon =0.1, 0.12, 0.14$. (a) Maximum height of solutions, $\max _zH_0(z;B,\epsilon )$, (b) $1-H_0(z=0;B,\epsilon )$ and (c) three example upper-branch solutions at $B=0.1$, which correspond to the locations indicated by the markers on (a) and (b).

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