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Flow rate–pressure drop relation for deformable shallow microfluidic channels

Published online by Cambridge University Press:  21 February 2018

Ivan C. Christov*
Affiliation:
Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544, USA School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA
Vincent Cognet
Affiliation:
Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544, USA École Normale Supérieure de Cachan, Cachan, CEDEX, France
Tanmay C. Shidhore
Affiliation:
School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA
Howard A. Stone*
Affiliation:
Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544, USA
*
†Email addresses for correspondence: christov@purdue.edu, hastone@princeton.edu
†Email addresses for correspondence: christov@purdue.edu, hastone@princeton.edu

Abstract

Laminar flow in devices fabricated from soft materials causes deformation of the passage geometry, which affects the flow rate–pressure drop relation. For a given pressure drop, in channels with narrow rectangular cross-section, the flow rate varies as the cube of the channel height, so deformation can produce significant quantitative effects, including nonlinear dependence on the pressure drop (Gervais et al., Lab on a Chip, vol. 6, 2006, pp. 500–507). Gervais et al. proposed a successful model of the deformation-induced change in the flow rate by heuristically coupling a Hookean elastic response with the lubrication approximation for Stokes flow. However, their model contains a fitting parameter that must be found for each channel shape by performing an experiment. We present a perturbation approach for the flow rate–pressure drop relation in a shallow deformable microchannel using the theory of isotropic quasi-static plate bending and the Stokes equations under a lubrication approximation (specifically, the ratio of the channel’s height to its width and of the channel’s height to its length are both assumed small). Our result contains no free parameters and confirms Gervais et al.’s observation that the flow rate is a quartic polynomial of the pressure drop. The derived flow rate–pressure drop relation compares favourably with experimental measurements.

Information

Type
JFM Papers
Copyright
© 2018 Cambridge University Press 
Figure 0

Figure 1. Three-dimensional schematic of the deformed geometry of a channel of length $\ell$ with an initially rectangular cross-section ($w\times h_{0}$). The volumetric flow rate is denoted by $q$ and $u(x,z)$ is the top wall’s deformation (the remaining walls are assumed rigid). Although not shown in this schematic, the top wall has a thickness $t$.

Figure 1

Table 1. Values of the physical parameters for the flow-rate-controlled PDMS microchannels experimental system S4 of Ozsun et al. (2013), which most closely matches the assumptions of our theoretical developments.

Figure 2

Figure 2. Contours of the axial velocity, $V_{Z}$, as a function of the $(X,Y)$ coordinates in the $Z=0.25$ cross-section of the channel with $Q=1$ and for different $\tilde{\unicode[STIX]{x1D6FD}}$ values, computed from (2.8) with the pressure given by the appropriate real root of (4.3) and the channel height given by (3.1) and (3.7). (a) Solid top wall ($\tilde{\unicode[STIX]{x1D6FD}}=0$). (b) Elastic top wall with $\tilde{\unicode[STIX]{x1D6FD}}=0.5$. (c) Elastic top wall with $\tilde{\unicode[STIX]{x1D6FD}}=1$.

Figure 3

Figure 3. (a) $H(X,Z)$ computed from (3.7) with $P(Z)$ computed from (4.3), for $\tilde{\unicode[STIX]{x1D6FD}}=2$ and $Q=1$; thick dashed line represents $1+\unicode[STIX]{x1D6FD}U_{max}(Z)$, thin dotted lines are a guide to the eye. (b) Maximum displacement, i.e. $H(0,0)-1=\unicode[STIX]{x1D6FD}U(0,0)$ calculated from (3.7) with $P(Z)$ computed from (4.3), as function of the flow rate $Q$ and different values of $\tilde{\unicode[STIX]{x1D6FD}}$.

Figure 4

Figure 4. (a) Pressure drop across the channel, $\unicode[STIX]{x0394}P=P(0)$, computed via (4.3), as a function of the flow rate $Q$ for different values of $\unicode[STIX]{x1D6FD}$. (b) Pressure $P$ as a function of the axial coordinate $Z$ computed by inverting (4.3); $Q=1$.

Figure 5

Figure 5. Dimensional flow rate–pressure drop relationship: comparison between our asymptotic theory (solid curve) (i.e. (4.7) evaluated at $z=0$), including a shaded trust region based on taking $E=1.6\times 10^{6}\pm 25\,\%$ MPa, and the experimental data from the S4 system of Ozsun et al. (2013) (symbols) with error bars smaller than the symbols according to Ozsun et al. (2013). The dotted line represents the standard lubrication-theory linear flow rate–pressure drop relation for a rigid rectangular channel, i.e. $\unicode[STIX]{x0394}p=12\unicode[STIX]{x1D707}\ell q/(h_{0}^{3}w)$.

Figure 6

Figure 6. Per cent error in the full pressure drop $\unicode[STIX]{x0394}P=P(0)$ as calculated via the approximate explicit relation (A 1), for a flow-rate-controlled situation ($Q=1$), and compared to pressure drop from the ‘full’ implicit relation (4.5), as a function of the compliance parameter $\tilde{\unicode[STIX]{x1D6FD}}$.