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Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study

Published online by Cambridge University Press:  21 October 2026

Uchenna Cosmas Ugwu*
Affiliation:
Human Kinetics and Health Education, University of Nigeria Nsukka, Nigeria
Agatha Nneka Obayi
Affiliation:
Human Kinetics and Health Education, University of Nigeria Nsukka, Nigeria
Christian Chukwuka Eze
Affiliation:
Human Kinetics and Health Education, University of Nigeria Nsukka, Nigeria
*
Corresponding author: Uchenna Cosmas Ugwu; Email: uchennacos.ugwu@unn.edu.ng
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Abstract

Depression in later life is a substantial yet under-recognized public health concern in low- and middle-income countries, including Nigeria, where rapid population aging heightens vulnerability. Evidence from community settings remains limited, particularly in southeastern Nigeria. This study examined the prevalence and sociodemographic factors associated with severe depressive symptoms among community-dwelling adults aged 60 years and older. A cross-sectional survey was conducted from June 2024 to August 2025 across 30 rural and urban communities in five southeastern states, using multistage purposive sampling to recruit 718 eligible participants. Data were collected through interviewer-administered questionnaires incorporating the Geriatric Depression Assessment Questionnaire and the Geriatric Depression Scale – Short Form. Severe depressive symptoms were highly prevalent. Advanced age, female gender, Christian religious affiliation, being married and living with family were significantly associated with higher odds of severe depressive symptoms, while educational level showed no association. Several associated sociodemographic factors contradicted widely held assumptions about the protective nature of traditional social structures, highlighting the need for further investigation into the quality and context of social relationships in later life. These findings underscore the urgent need for routine geriatric mental health screening, community-based support strategies and culturally responsive interventions within Nigeria’s primary care and social welfare systems.

Information

Type
Research Article
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NC
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial licence (http://creativecommons.org/licenses/by-nc/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use.
Copyright
© The Author(s), 2026. Published by Cambridge University Press
Figure 0

Table 1. Sociodemographic characteristics of the participants (N = 718)Table 1. long description.

Figure 1

Table 2. Chi-square analysis of geriatric depression by sociodemographic variables (N = 718)Table 2. long description.

Figure 2

Table 3. Odds ratios of geriatric depression by sociodemographic factors (Unadjusted, derived from bivariate analyses, N = 718)Table 3. long description.

Author comment: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R0/PR1

Comments

Date: November 28, 2025

To

The Editor-in-Chief

Global Mental Health

Subject: Submission of manuscript titled “Status of Geriatric Depression among Older Adults in Rural-Urban Communities Across Southeastern States of Nigeria: A Cross-Sectional Study”

Dear Sir,

We are submitting original article titled “Status of Geriatric Depression among Older Adults in Rural-Urban Communities Across Southeastern States of Nigeria: A Cross-Sectional Study” for consideration for publication in the Global Mental Health

Our study is relevant because the study sought to determine the prevalence of geriatric depression and identify its sociodemographic predictors among older adults in southeastern Nigeria. The most important conclusion which can be drawn from our study was that geriatric depression is highly prevalent among older Nigerians and significantly influenced by age, gender, religion, and living arrangement. Culturally sensitive mental health strategies and strengthened geriatric care policies are urgently required.

The manuscript has not been published and is not under consideration for publication in any other journal. Instructions to the author were read. We accept all conditions and publication rights. All authors have read and approved the manuscript and its submission to the journal.

We have no conflicts of interests to declare. We have no funding sources to declare

Thank you,

Yours sincerely,

November 28, 2025

Uchenna Cosmas Ugwu

(For authors)

Review: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R0/PR2

Conflict of interest statement

Reviewer declares none.

Comments

Congratulations on conducting the study on this scale. Good sample size across urban/rural.

However, I raise some concerns and questions below:

Abstract

- please add the word ‘purposive’ to sampling

Methods

- Stage 3 should have been random, or at least, consecutive sampling. Your purposive sampling method has most likely led to your unusually high response rate of 99.7%. Please explain more about your methods which could explain this, such as where were they approached (in clinics/at home?), and where did they complete the survey? Then add this specific detail to your limitation of purposive sampling.

- Please describe the GDS (number of items, timeframe, severity categories, depression threshold etc).

- Who were the 30 research assistants?

Results

- Move the mean age from above into the Sample Characteristics.

- Do you have any more information about the category Tertiary education - does this mean university? If so, that is a very high figure.

- Remove the % sign in Table 1 (Living Situation).

- You report that 100% of participants score either in the mild or severe categories on the GDS. Did no single participant score in the Normal or Moderate categories? If not, why?

- Based on your Chi results, education level was not sig predictor. However, as per above, 61% of your sample was tertiary educated and with severe levels of depression symptoms - why do you think this is in your sample?

Discussion

- Numerous studies cite the over-estimation of symptoms with screening tools, and the need to use gold standard diagnostic interviews to ensure better accuracy of prevalence estimates. Please cite a reference of a study using a gold standard diagnostic interview to estimate late life depression in Sub-Saharan Africa to contextualize your very high severe depression results.

Review: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R0/PR3

Conflict of interest statement

Reviewer declares none.

Comments

The study has significantly contributed to geriatric mental health in Nigeria, with a sound methodology and cultural relevance. Here are my suggestions:

1. What is the cut-off point used to dichotomise the outcome variable as having mild or severe depression? This should be added to the methodology section.

2. The frequencies and percentages reported in Table 2 were also part of Table 3. I suggest that columns n, Severe, and Mild be removed from Table 3. The authors may want to add the crude odds ratio (the unadjusted odds ratio) instead of the repetition if they wish.

3. Was it a multivariable logistics regression that was done in the analysis reported in Table 3? If yes, then Table 3 should inform the reader that the adjusted odds ratio was reported, and this should also be part of the methodology.

4. The p-values of 0.0001 should be replaced with <0.001

5. The table headings of the tables should be bolded, as well as the first row in the tables (Table headers)

Review: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R0/PR4

Conflict of interest statement

NIL

Comments

I consider this manuscript to be ambitious and timely, addressing an important gap in community-based data on geriatric depression in Nigeria. The writing is generally clear, the structure follows STROBE recommendations, and the policy orientation is appropriate for the journal. That said, I have several substantive concerns that relate to measurement, analysis, and interpretation, which currently limit the credibility and interpretability of the findings.

My most significant concern is the reporting and interpretation of the outcome variable. The authors state that “severe depression was highly prevalent (61.3%)” and repeat this phrasing throughout the abstract, results, and discussion. However, the manuscript does not clearly justify how “severe depression” was operationalized using the Geriatric Depression Scale–Short Form (GDS-15), which is a screening tool rather than a diagnostic instrument. Moreover, the results indicate that participants were classified only as having “severe” (61.3%) or “mild” (38.7%) depressive symptoms, with no category representing non-depressed individuals. This raises concerns about outcome misclassification and likely overestimation of burden. I recommend that the authors explicitly report the GDS-15 cut-off scores used, present the full distribution of normal, mild, moderate, and severe symptom categories, and consistently refer to the outcome as “severe depressive symptoms” rather than “severe depression” to avoid diagnostic overreach.

A second major concern relates to the analytical strategy used to identify “predictors” of depression. In the abstract and results, the authors state that “advanced age, female gender, Christian religious affiliation, being married, and living with family significantly increased the odds of severe depression.” However, all analyses presented appear to be bivariate, relying on chi-square tests and unadjusted odds ratios. No multivariable regression analysis is reported. Given the strong interrelationships among age, gender, marital status, education, religion, and living arrangements, these findings cannot be interpreted as independent predictors. I strongly recommend that the authors conduct a multivariable logistic regression and revise the language throughout the manuscript to reflect adjusted associations. Without this, claims of prediction and independence are not statistically supported.

Relatedly, I am concerned about the interpretation of some sociodemographic variables, particularly religion, marital status, and co-residence. For example, the manuscript states that “Christians were nearly four times more likely to experience severe depression” (OR = 3.75), and later suggests that certain Christian contexts may “emphasize moral perfectionism or spiritual interpretations of distress.” While these interpretations are intriguing, they extend beyond what can reasonably be inferred from the available data, especially in the absence of measures of religiosity, denomination, religious coping, or help-seeking behaviors. Similar concerns apply to the interpretation of marriage and co-residence as risk factors. I encourage the authors to frame these findings more cautiously as context-specific associations and to explicitly acknowledge the likelihood of residual confounding.

The sampling strategy also requires clearer alignment with the claims made in the manuscript. While the authors describe the study as “regionally representative” and as providing “robust population-level evidence,” communities and participants were selected purposively at multiple stages. Although this approach may be pragmatic, it limits generalizability and introduces potential selection bias. I recommend revising claims of representativeness throughout the manuscript and expanding the limitations section to reflect these methodological constraints more explicitly.

In addition, the sociodemographic profile of the sample raises questions. The finding that “most had attained tertiary education (67.1%)” among adults aged 60 years and older in southeastern Nigeria appears unusually high and may reflect urban or pensioner bias, misclassification of education categories, or selective participation. The authors should clarify how educational attainment was defined and discuss how this distribution may affect interpretation of the findings.

There are also several methodological and reporting issues that warrant attention. The presentation of the sample size calculation uses a nonstandard formulation of Cochran’s formula (“n = 4GD/P²”), which should be clarified and rewritten using conventional notation. The cross-sectional data collection period spans more than one year (June 2024 to August 2025), yet potential temporal or seasonal variability is not discussed. Finally, the manuscript contains duplicated references (e.g., Akinyemi et al., 2020 appears twice), minor typographical errors, and formatting inconsistencies in the tables that should be corrected.

Recommendation: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R0/PR5

Comments

No accompanying comment.

Decision: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R0/PR6

Comments

No accompanying comment.

Author comment: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R1/PR7

Comments

No accompanying comment.

Review: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R1/PR8

Conflict of interest statement

Reviewer declares none.

Comments

I appreciate the authors' effort to address an important public health issue in a low-resource setting. The study highlights a high prevalence of severe depressive symptoms and explores sociodemographic associations, which could contribute to the limited literature on geriatric mental health in Nigeria. However, I identified several errors, issues, and inconsistencies that undermine the manuscript’s rigor and clarity. I’ll discuss these in detail, grouped by section, and suggest corrections to improve the paper.

Starting with the abstract and impact statement, there’s a grammatical error in the abstract where “Severe depressive symptoms was highly prevalent (61.3%)” should be “were” to agree with the plural subject “symptoms.” This minor issue recurs in similar phrasing throughout the manuscript, such as in the results section. Additionally, the abstract states that 61% of participants were tertiary-educated, but Table 1 and the results text correctly report 67.1% (482 out of 718). This inconsistency suggests a calculation or typing error; I recommend verifying all percentages against the data and correcting to 67.1% for accuracy. The impact statement is well-written but overstates the robustness of the evidence by calling it “robust, community-based evidence” without acknowledging the purposive sampling limitations upfront, which could mislead readers about generalizability.

In the introduction, the references are generally appropriate, but some cite future or recent publications like Ugwu & Ene (2025) and National Health Research Ethics Committee (2025), which is fine given the submission date of February 2026, but I suggest ensuring these are indeed published or accessible. There’s no major inconsistency here, but the section could benefit from more discussion on why southeastern Nigeria was chosen specifically, beyond scarcity of data, to strengthen the rationale. For correction, I propose adding a sentence on regional sociocultural factors, like the predominance of Igbo culture and Christianity, to better contextualize the findings on religious affiliation.

The methods section has several notable issues. First, the sample size calculation appears erroneous. The formula [n = 4GD/P²] with G=75.6%, D=24.4%, and P=11.34 yields approximately 57, not 645 as stated. This seems like a misapplication of Cochran’s formula; the standard is n = Z² p (1-p) / e², where e is the absolute margin of error (typically 0.05). If the authors intended a relative precision or different parameter, it needs clarification; perhaps P is meant to be 5% absolute, which would give n ≈ 384 before adjustment. I strongly recommend recalculating and explaining the formula clearly, as this error questions the study’s power. Second, the ethical approval is from the “Federal Ethics Committee of Nigeria,” but the reference lists it as “National Health Research Ethics Committee (Nigeria).” This inconsistency should be resolved by using the correct name (NHREC) throughout. Third, the languages for translation (Hausa, Igbo, Yoruba) include Hausa and Yoruba, which are not primary in southeastern Nigeria (mostly Igbo-speaking); if not used, mention why they were included or remove to avoid confusion. The 35-minute training for assistants seems brief for topics like cultural sensitivity and instrument administration; suggest expanding to describe content or justify duration. Finally, the GDAQ’s Cronbach’s alpha of 0.85 is reported, but since it includes sociodemographic items (not scaled), clarify if this is for the GDS-15 section only.

The results section is mostly consistent, but the absence of any “normal” GDS-15 scores (all participants ≥6) is striking and likely reflects selection bias from purposive sampling in high-risk areas, as noted. However, this makes the 61.3% severe prevalence potentially inflated and non-representative; I suggest emphasizing this more prominently as a limitation here, not just in discussion. Table 1 is clear, but Table 2 has a p-value of 0.007 for living situation, while text says 0.0007 - correct to match (likely 0.001 or exact). In Table 3, odds and OR are presented without frequencies (good to avoid duplication), but for gender, the OR is for males (0.29), while text discusses females; suggest adding a note on reference categories for clarity.

The discussion appropriately interprets findings conservatively, acknowledging bivariate limitations and residual confounding, which is a strength. However, the counterintuitive associations (e.g., marriage and co-residence with higher depression) are well-explained, but the Christian affiliation finding is over-speculated without data on religiosity - the authors already note this, but I recommend toning down to avoid implying causality. The comparison to Ghana’s 18.3% prevalence using MINI is excellent, but add that GDS-15 cutoffs may over-estimate; suggest future studies use diagnostic tools.

Recommendation: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R1/PR9

Comments

No accompanying comment.

Decision: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R1/PR10

Comments

No accompanying comment.

Author comment: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R2/PR11

Comments

No accompanying comment.

Recommendation: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R2/PR12

Comments

No accompanying comment.

Decision: Status of geriatric depression among older adults in rural-urban communities across southeastern states of Nigeria: A cross-sectional study — R2/PR13

Comments

No accompanying comment.