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An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya

Published online by Cambridge University Press:  29 July 2026

Teresia Mutavi
Affiliation:
Department of Psychiatry, University of Nairobi, Kenya
Tessa Concepcion
Affiliation:
Department of Global Health, University of Washington, USA
Mansurat Raji
Affiliation:
Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, USA
Anne Mbwayo
Affiliation:
Department of Psychiatry, University of Nairobi, Kenya
Stella Waruinge
Affiliation:
Health Directorate, Mental Health Unit, Nairobi County Government, Kenya
Shannon Dorsey
Affiliation:
Department of Psychology, University of Washington, USA
Brandon A. Kohrt
Affiliation:
Center for Global Mental Health Equity, George Washington University, USA
Gloria Pedersen
Affiliation:
Center for Global Mental Health Equity, George Washington University, USA Mental Health Program, Partners in Health, USA
Alison Schafer
Affiliation:
Mental Health, Brain Health and Substance Use, World Health Organization, Switzerland
Muthoni Mathai
Affiliation:
Department of Psychiatry, University of Nairobi, Kenya
Pamela Y. Collins*
Affiliation:
Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, USA
*
Corresponding author: Pamela Y. Collins; Email: pamela.collins@jhu.edu
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Abstract

This study evaluated 1) foundational helping competencies for Non-Specialist Providers (NSPs) trained in a transdiagnostic CBT-based intervention (PRO-ACT) for adolescents with anxiety and depression in Nairobi, Kenya and 2) preliminary clinical outcomes for adolescents receiving PRO-ACT. Seventeen NSPs were trained and assessed using role plays at pre-training, post-training, and post-supervision using the Enhancing Assessment of Common Therapeutic Factors (ENACT) tool, via a pre-post design (no control group). Eighteen adolescents were enrolled, received 4–6 PRO-ACT sessions, and assessed using the Patient Health Questionnaire-9 (PHQ-9) and Revised Children’s Anxiety and Depression Scale (RCADS-25). There were no significant changes in NSPs’ competencies from pre- to post-training. From pre-training to post-supervision, NSPs’ Level 1 (Potentially harmful) scores significantly decreased (−1.12 items; 95% CI: −2.10, −0.15; p = 0.026) and Level 3 or 4 (“Basic” or “Advanced competency”) significantly increased (2.12; 95% CI: 1.21, 3.04; p < 0.001). Adolescents had no significant change in mean PHQ-9 scores. RCADS scores decreased significantly for depression (−3.00 points; 95% CI: −5.45, −0.55; p = 0.020) and anxiety (−3.39 points; 95% CI: −6.17, −0.61; p = 0.020). NSPs’ foundational helping competencies improved significantly during clinical supervision. Client outcomes were promising, warranting a larger rigorous trial.

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Type
Research Article
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NC
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial licence (http://creativecommons.org/licenses/by-nc/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use.
Copyright
© The Author(s), 2026. Published by Cambridge University Press
Figure 0

Table 1. Socio-demographic characteristics of NSPs trained in Nairobi, Kenya. (N = 17)Table 1. long description.

Figure 1

Table 2. Comparison of total number of items at ENACT Level 1 (“potentially harmful”) and Levels 3 or 4 (“basic or advanced competency”), between pre-training, post-training, and post-supervision timepointsTable 2. long description.

Figure 2

Figure 1. Frequency of Level 1 and Level 3/4 ENACT competency scores among NSPs, by ENACT item and assessment timepoint.Figure 1. long description.

Figure 3

Table 3. Socio-demographic and baseline characteristics of screened, eligible, and participating adolescents in Nairobi, KenyaTable 3. long description.

Figure 4

Table 4. Pre- and post-test screening scores for anxiety and depression (n = 18)Table 4. long description.

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Author comment: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R0/PR1

Comments

02/01/2026

Chief Editor

Cambridge Prisms: Global Mental Health

Dear Chief Editor,

Please consider our manuscript, “An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya,” for publication as an Original Research Article in the Cambridge Prisms: Global Mental Health journal.

Adolescents in low-resource settings have limited access to evidence-based mental health care, and there is an urgent need for scalable approaches that can be delivered within existing community and primary care settings. In this study, community health promoters were trained to deliver a brief, manualized transdiagnostic cognitive-behavioral therapy–based intervention (Psychoeducation, Relaxation, Problem-solving, Activation, and Cognitive Coping Therapy). We evaluated changes in provider helping skills following structured training and clinical supervision, and changes in adolescent symptoms of anxiety and depression following delivery of the intervention.

Our findings show that non-specialist providers demonstrated significant improvements in foundational helping skills after training and supervised practice. Adolescents receiving the intervention experienced meaningful reductions in anxiety symptoms and improvements in one of the measures of depression used. These results add practical evidence that clinical supervision is a key component in strengthening the acquisition and application of helping skills among non-specialists delivering structured, evidence-informed psychological care. The work directly supports policy and program action by informing how task-sharing models can be strengthened and scaled to expand access to adolescent mental health services in low-resource settings.

The manuscript is original and, to the best of our knowledge, has not been published elsewhere and is not under consideration by another journal. No abstract or other substantial part of the manuscript has been posted online (for example, as a preprint, conference proceeding, report, or unpublished paper). In addition, the manuscript is within the journal’s recommended word length, and the tables and figures are within the journal’s limits. There are no deviations from the recommended guidelines listed for manuscript publication.

Thank you for your consideration.

Pamela Y. Collins

Bloomberg Centennial Professor and Chair | Department of Mental Health

Bloomberg School of Public Health

Professor | Department of Psychiatry & Behavioral Sciences

The Johns Hopkins University School of Medicine

Review: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R0/PR2

Conflict of interest statement

I work at a non-profit, Shamiri Institute.

Comments

Some of the findings of this study are quite interesting (e.g., supervision driving most improvement in CHW performance), and I appreciate the effort put into this study. That said, I have some concerns about the analyses and reporting (below) and extent of engagement with past literature. Additionally, the sample size is small, limiting ability to detect results if present, and the relation between the different study elements is sometimes unclear. More specific comments are provided below:

ABSTRACT

What do the numbers provided in the results section of the abstract refer to? Changes from pre-to-post, raw? Effect sizes?

Also, these results don’t seem to match what is reported later in the results section. The authors should check their reporting, and clarify what results exactly they are reporting.

INTRODUCTION

There are a few typos in the background section.

This section is generally clear and organized, and covers relevant information, but has fewer references to the relevant literature than might be expected to optimally discuss relevant past findings.

METHODS

More information about this study’s relation to the broader EQUIP study across 6 LMICs would be helpful.

Could the authors say more about the “informal settlement” in which this was conducted?

How was a score of 5 or higher selected on the SBQ?

RESULTS

Was this study pre-registered, or was there any analysis plan? Some of the analyses rely on what seem to be arbitrary cut-offs, and if they were pre-specified, that would strengthen the study. Otherwise, the authors should better clarify and justify some of the analyses conducted, especially those involving arbitrary groupings or cutoffs.

DISCUSSION

The discussion could be improved greatly by increasing references to past literature; the findings should be considered in the context of previous related studies and findings, which is currently not done thoroughly.

Were two out of five adolescents screened out due to suicide risk, or due to more elevated symptoms of depression OR suicide risk?

Review: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R0/PR3

Conflict of interest statement

Reviewer declares none.

Comments

It was a pleasure to review “An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya.” This is an interesting paper with important potential contributions. Please find comments/concerns below:

Introduction:

-Minor: Add period after first sentence of second paragraph.

-It might be clearer to define “task-shifting/task-sharing” when the utility of non-specialist providers is first introduced in paragraph 2.

-Minor: Typo in this sentence (remove word “world”?): “Combining broader-reaching transdiagnostic, multi-problem interventions with task-shifting/task-sharing, through which non-specialists receive abbreviated training to assume some of the roles traditionally performed by mental health professionals (11, 12), could help to optimize youth mental health care in Nairobi.”

-Different terms are used for non-specialist providers throughout the introduction (e.g., non-specialist providers/non-specialist/non-specialist providers). It would be clearer to use one consistent term and then make the direct link that in this study the non-specialist providers are the community health promoters.

Methods:

-Minor: Missing period after the second sentence of the first paragraph in this section (Line 86).

-Minor: The acronym PRO-ACT is used at the start of the methods and then spelled out for the first time later under the “Intervention and provider training” section. Please use the full name at the start of the methods.

-In the definition of “foundational helping competencies,” it would be helpful if the authors provided a couple of examples.

-The paper could be strengthened by adding a table within the manuscript describing the 15 competency items across the 5 categories. The supplemental material is helpful, but terms related to the competency items are used in the results without sufficient context in the main body of the manuscript.

-“Lay counselors” is used when describing TF-CBT/CETA. Readers outside the field may not know that lay counselors are considered non-specialist providers. Please make that connection explicit, or use the term “non-specialist providers” consistently throughout.

-Please make it clear that Mkuru kwa Njenga is located in Nairobi.

-How many hours was the training of the CHPs in total? The paper states 6 days, but knowing the actual number of hours would be helpful for readers.

-More details about the phone-based training would be helpful. How did this work? What does a “mobile phone-based, interactive approach that emphasized practical skill development” actually look like in practice?

-Who were the “lay trainers”? What does “lay trainer” mean, and how were they trained?

-Minor: “Service users” does not need to be capitalized (Line 117).

-How did the Nairobi County Department of Health identify CHPs? Were there any selection criteria at this stage, such as age or background?

-Minor: Please rephrase the following sentence for clarity: “Community Health Promoters recruited from the community among youth known to be in distress or from families in crisis.”

PHQ-9: Please explain why the English version was used.

RCADS: The note “RCADS results are not published and available from the author” should read “and are available from the author.” Please also clarify what this statement is referring to, as it is currently confusing.

Results:

The following statement should be moved to the methods section: “All client-reported outcomes (RCADS; PHQ-9) were collected and recorded in Kenyan English.”

Relatedly, the terms within the domain of “Understand” — including “Social functioning,” “Explanatory models,” “Involve family,” “Coping,” and “Psychoeducation” — are used without proper definitions in the main body of the manuscript.

Discussion:

The authors do not sufficiently highlight the interesting strength of the phone-based training approach. Has this approach been used in other studies? This warrants further discussion.

Please rephrase the following statement for clarity. In particular, explain why the finding is confusing rather than simply noting that it is: “The PHQ-9 has been validated in Kenya (21), and we observed significantly less change in the symptom profile on the PHQ-9 compared to the RCADS (and the opposite direction for boys on the RCADS depression vs. PHQ-9, which is a confusing finding).”

It would be helpful to discuss gender dynamics in both the recruited sample of adolescents (13 of 18 identifying as girls) and the selection of CHPs (10 of 17 were women). Was it more difficult to engage adolescent boys? Was it more difficult to recruit male CHPs?

Relatedly, the authors might also discuss the smaller decreases in symptoms (RCADS) observed among adolescent boys.

The paragraph connecting findings to other interventions delivered by non-specialist providers lacks sufficient engagement with the relevant literature. There are numerous examples from the Kenyan context of non-specialist-delivered mental health interventions, including examples with adolescents. The examples currently cited do not appear to be child or adolescent interventions.

Additionally, there are child and adolescent interventions that have used the ENACT measure. The relevant literature in the discussion is lacking in this regard.

The following statement requires additional context: “The evaluation of this intervention indicated that it was effectively delivered.” What was the measure of delivery effectiveness?

There is no mention of intervention fidelity in the paper. Was fidelity rated? If not, this should be acknowledged as a limitation.

The paragraph on suicidality contains no citations. Adolescent suicidality has been studied in Kenya, including in informal settlements. The authors should situate their findings within what is already known about suicidality in similar contexts.

In the non-specialist provider literature, there is growing evidence regarding the promise of selecting providers with shared social characteristics (ie., social proximity) to the service users. What characteristics did the CHPs share with the service users, and could this have influenced clinical outcomes?

Review: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R0/PR4

Conflict of interest statement

Reviewer declares none.

Comments

This study addresses an important gap in adolescent mental health services in low-resource settings and makes a meaningful contribution to the literature on task-sharing and competency-based training for lay providers in Kenya. The use of the EQUIP platform and ENACT tool in a real-world implementation context is a notable strength, and the authors are commended for conducting this work during an exceptionally challenging period. Below are suggestions for strengthening the manuscript to improve clarity of methods and findings.

Abstract

• The RCADS outcome values reported in the abstract (depression: 8.9, 95% CI: 1.8–16.0, p=0.017; anxiety: 7.7, 95% CI: 1.7–13.7, p=0.015; total: 9.2, 95% CI: 4.2–14.1, p=0.001) do not match those reported in the Results section and Table 4 (depression: −3.0, 95% CI: −5.45 to −0.55, p=0.020; anxiety: −3.39, 95% CI: −6.17 to −0.61, p=0.020; total: −6.44, 95% CI: −10.10 to −2.79, p=0.002). The p-values also differ slightly across sections.

• The abstract would benefit from greater clarity about the study design. The term proof-of-concept appears later in the objectives section but is not defined in the abstract. It would be helpful to note that the study is a pilot pre–post study without a control group.

Impact Statement

• Describing findings as policy- and program-relevant evidence slightly overstates the contribution of a small proof-of-concept pilot can support with confidence. The authors should consider using more qualified language.

Background

• The background provides useful and clear context on adolescent mental health in Kenya.

• The rationale for combining the EQUIP competency framework with the PRO-ACT intervention would be helpful to articulate early in the section. One sentence early in the background explaining the relationship between the two would close this gap.

• The background mentions TF-CBT as an existing intervention in Kenya but does not explain what gap PRO-ACT is intended to fill relative to already-validated options in the region. A brief statement here on why a new intervention is needed would strengthen the rationale for the study.

• The terms task-shifting and task-sharing are used interchangeably throughout the paper, which reflects a common practice in the global mental health literature. However, given that these terms carry distinct meanings in some frameworks, the authors should briefly clarify which model this study reflects and use that term consistently thereafter.

Methods

Study Design

• The study is described as a proof-of-concept evaluation, but it would be clearer to also explicitly label the design as pre-post. Adding one sentence early in the Methods would help orient the reader before the details unfold; for example. “This pilot pre–post study was embedded within a larger multi-country EQUIP project.”

• It is a strength that provider training outcomes and client outcomes are both included. It would be helpful for a range of readers if the rationale for measuring both was explained more clearly.

Intervention Description

• The authors cite the effectiveness of TF-CBT and CETA as part of the rationale for selecting PRO-ACT, but the specific advantage of PRO-ACT over these existing interventions is not explained clearly. One sentence clarifying this would make the rationale for the intervention selection much clearer.

Participants

• There is a discrepancy in the age eligibility criteria as reported across the paper. The Participants section specifies 12 to 17 years, while a table footnote states that the study eligibility criteria were 12 to 20 years. The authors should reconcile these conflicting statements and clarify in the main text what the eligibility criteria were (and, if 12-20, any reasons contributing to all participants ultimately falling within the 12 to 17 range).

Measures

• The authors should consider including a dedicated measure sub-heading.

• The rationale for using both the PHQ-9 and RCADS could be stated more explicitly, particularly given that the two measures yielded divergent findings.

• Although a validated Swahili version of both the PHQ-9 and RCADS existed, all assessments were conducted in English. A brief justification for this decision would be helpful, given that participants were from an informal settlement and may have had varying English proficiency.

Procedures

• More detail would be helpful regarding the content and structure of supervision sessions. Knowing that supervision was weekly via WhatsApp is a useful starting point, but what was discussed and how case quality was monitored is not described.

• The intervention is described as a four- to six-session modular protocol, yet all participants in this pilot received four sessions. It would be helpful to clarify whether sessions were standardized to four for the purposes of this pilot, and if so, whether this was a deliberate protocol decision or how delivery unfolded in practice.

• The training duration of six days, mostly half-days, is relatively brief for CBT-based skills. A brief justification or reference to comparable training programs in similar settings would help readers assess the adequacy of this approach.

• The authors stated ENACT ratings were partly conducted by two researchers from the study program. It is unclear whether these researchers were also involved in delivering the training or intervention. The authors should clarify their roles and describe what steps were taken to ensure rater independence.

Statistical Analysis

• Given the small and exploratory nature of this pilot, it would be helpful to note that all analyses were intended to generate preliminary signals, and that results should be interpreted accordingly.

• The rationale for using a difference-in-differences approach with such a small sample could be briefly explained.

Results

Provider Training Outcomes

• Authors should consider reporting effect sizes alongside p-values to help interpretation, particularly given the small sample. The mean ENACT improvement from 1.89 to 2.12 on a 1 to 4 scale is statistically significant but modest; reporting the effect size estimates would help assess its practical magnitude.

• Given there was virtually no improvement on Risk Assessment competency, and 43% of screened adolescents were referred due to suicidality, this pattern warrants more prominent attention.

Client Intervention Outcomes

• The first two paragraphs within Client Intervention Outcomes section are a bit difficult to follow and repetitive, though Figure 2 is clearer. The text could be made much clearer and concise, and it is important to expand on why 20 of the 39 eligible participants did not elect to participate in the intervention.

Discussion

• The discussion appropriately situates findings within the task-sharing literature but sometimes overstates the implications of a small pilot study. Statements about scalability and intervention potential should be framed more cautiously and qualified as directions for future research.

• The discussion should engage more directly with why the PHQ-9 did not show significant improvement while the RCADS did, especially given that the PHQ-9 was chosen for inclusion (presumably because the study team deemed it the most valid and relevant for the symptoms the intervention is intended to target). The current treatment of this as a passing observation, described as a confusing finding, is insufficient. The authors should offer possible explanations, for example were the differences in construct coverage, age-appropriateness, or the sensitivity of each measure in this sample.

• The finding that improvements occurred mainly after supervision rather than immediately post-training is noteworthy. The discussion would benefit from exploring what aspects of supervision may have driven competency development.

• COVID-19 is cited as a possible explanation for symptom instability, but this cannot be assessed from the study design and should be framed as post-hoc.

• Recruiting youth ‘known to be in distress’ is a pragmatic approach that reflects how task-shifting programs operate in real-world settings. However, the authors should clarify what criteria CHPs used to identify these youth, and briefly acknowledge that without a standardized referral process, the sample may skew toward more visible or severe presentations, which has implications for who the findings generalize to.

Limitations

• There is no mention of intervention fidelity monitoring for PRO-ACT session delivery. For a proof-of-concept pilot, this is understandable, but the authors should acknowledge it and note that weekly supervision served as the primary mechanism for quality assurance.

• Reliance on self-report measures only could be noted as a limitation.

• Related to recruitment, authors should consider reflecting on limitations due to relying on CHP referral (i.e, whether that is the ideal source for adolescent referral or whether other procedures might have led to higher levels of engagement). Related, more should be discussed related to the large number of adolescents who elected not to participate and how that may influence conclusions around feasibility and acceptability and how it might point to the need for changes in implementation strategy.

Conclusion

• Given the study design, the conclusion should consistently emphasize feasibility and preliminary signals rather than clinical effectiveness.

• The final paragraph describing the ENACT tool reads more like a methodological note than a conclusion and could be streamlined or integrated earlier in the paper.

Recommendations

• Some recommendations follow directly from the study findings, such as the importance of sustained supervision and the need for effectiveness trials. Others, such as hybrid training approaches and alternative screening tools, are broader suggestions not directly supported by this pilot. The authors should distinguish between these two categories, for example by labeling them explicitly as study-supported versus directions for future work.

• This section should be reframed as implications and integrated into the Discussion section.

Recommendation: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R0/PR5

Comments

No accompanying comment.

Decision: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R0/PR6

Comments

No accompanying comment.

Author comment: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R1/PR7

Comments

06/12/2026

Editor-in-Chief,

Cambridge Prisms: Global Mental Health

Dear Editor-in-Chief,

Please consider our manuscript, “An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya,” for publication as an Original Research Article in the Cambridge Prisms: Global Mental Health journal.

Adolescents in low-resource settings have limited access to evidence-based mental health care, and there is an urgent need for scalable approaches that can be delivered within existing community and primary care settings. In this study, community health promoters were trained to deliver a brief, manualized transdiagnostic cognitive-behavioral therapy–based intervention (Psychoeducation, Relaxation, Problem-solving, Activation, and Cognitive Coping Therapy). We evaluated changes in provider helping skills following structured training and clinical supervision, and changes in adolescent symptoms of anxiety and depression following delivery of the intervention.

Our findings show that non-specialist providers demonstrated some improvements in foundational helping skills after training and supervised practice. Adolescents receiving the intervention experienced meaningful reductions in anxiety symptoms and improvements in one of the measures of depression used. These results provide preliminary evidence and suggest that clinical supervision is a key component in strengthening the acquisition and application of helping skills among non-specialists delivering structured, evidence-informed psychological care. The work contributes to existing literature and evidence by informing how task-sharing models can be strengthened and scaled to expand access to adolescent mental health services in low-resource settings.

The manuscript is original and, to the best of our knowledge, has not been published elsewhere and is not under consideration by another journal. No abstract or other substantial part of the manuscript has been posted online (for example, as a preprint, conference proceeding, report, or unpublished paper). In addition, the manuscript is within the journal’s recommended word length, and the tables and figures are within the journal’s limits. There are no deviations from the recommended guidelines listed for manuscript publication.

We have revised the manuscript in response to the editor’s and reviewers' comments and have submitted a point-by-point response along with the revised manuscript.

Thank you for your consideration.

Sincerely,

Pamela Y. Collins, MD, MPH

On behalf of all manuscript authors.

Review: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R1/PR8

Conflict of interest statement

None

Comments

Thank you for the opportunity to review this manuscript. I found it to be a thoughtful and well-written contribution to the literature. The topic is important and timely, and the authors provide a clear rationale for the study.

The manuscript is well structured, the methods are appropriate, and the findings are presented in a clear and meaningful way. The discussion appropriately situates the findings within the broader literature and highlights relevant implications for research and practice.

Recommendation: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R1/PR9

Comments

No accompanying comment.

Decision: An evaluation of non-specialist training and delivery of a brief cognitive-behavioral therapy-based transdiagnostic intervention for adolescents with depression and anxiety in Nairobi, Kenya — R1/PR10

Comments

No accompanying comment.