While Eustachian tube dysfunction is a known comorbidity of chronic rhinosinusitis with nasal polyps, the prevalence of Eustachian tube dysfunction symptoms in this population is poorly understood.

Retrospective analysis of patient-reported sino-nasal (Sino-Nasal Outcome Test 22) and ear (Eustachian Tube Dysfunction Questionnaire 7) symptoms with type-2 markers (peripheral blood eosinophils and total immunoglobulin E, Nasal Polyp Score and Lund-Mackay Score on computed tomography in chronic rhinosinusitis with nasal polyps (study group) and non–chronic rhinosinusitis patients (control group). The control group were patients presenting with symptoms of chronic rhinosinusitis and Eustachian tube dysfunction with normal endoscopy and computed tomography sinus scan.

Chronic rhinosinusitis with nasal polyps patients were significantly older, had a higher proportion of males and higher levels of type-2 markers. There was no significant difference in Sino-Nasal Outcome Test 22, Eustachian Tube Dysfunction Questionnaire 7 and the proportion of patients with Eustachian tube dysfunction between the groups. Sino-Nasal Outcome Test 22, Sino-Nasal Outcome Test 5 and Sino-Nasal Outcome Test 22 ear domain correlated significantly with Eustachian Tube Dysfunction Questionnaire 7 in chronic rhinosinusitis with nasal polyps patients.

The clinical relevance of the Eustachian Tube Dysfunction Questionnaire 7 in chronic rhinosinusitis with nasal polyps is rather debatable as our findings reveal the presence of elevated scores not only in chronic rhinosinusitis with nasal polyps but also in the control group.

To assess the efficacy of intranasal cryotherapy to treat chronic rhinitis refractory to medical therapy.

An evaluation was performed for all patients (n = 36) with chronic rhinitis refractory to medical treatment who underwent intranasal cryotherapy between 2022 and 2024 at this centre. The primary outcome measures were changes in validated pre- and post-operative scoring systems (Total Nasal Symptom Score, Sino-Nasal Outcome Test 22 (SNOT-22), Nasal Obstruction Symptom Evaluation and peak inspiratory nasal flow).

Objective scoring pre- and post-procedure showed statistically significant improvement across all measures (p < 0.001): mean Total Nasal Symptom Score (12 hours) 8.4 to 5.3, Total Nasal Symptom Score (2 weeks) 9.2 to 5.9, SNOT-22 56 to 31, Nasal Obstruction Symptom Evaluation 57.5 to 28.5 and peak inspiratory nasal flow 98 to 138 l/min.

This is the only dataset for patients receiving intranasal cryotherapy in the UK to date and follows patients over a two-year period. The results support the ongoing use of intranasal cryotherapy for sustained treatment of refractory chronic rhinitis.

This study investigated whether inferior turbinate reduction combined with septoplasty improves patients’ outcomes, as assessed by objective and subjective methods.

A single-centre, parallel-group, randomised, open-label trial was conducted at a tertiary hospital ENT clinic. Patients who underwent septoplasty were divided into two groups: group A underwent septoplasty with radiofrequency ablation; group B underwent only septoplasty. All patients were assessed before and three months after surgery using acoustic rhinometry and peak nasal inspiratory flow measurements, as well as Nasal Obstruction Symptom Evaluation scale and Sino-Nasal Outcome Test-22 scores.

Seventy-four patients completed the study (36 in group A and 38 in group B). The patients in both groups showed significant improvements in acoustic rhinometry and peak nasal inspiratory flow measurements and in Nasal Obstruction Symptom Evaluation scale and Sino-Nasal Outcome Test-22 scores after the surgery (p < 0.05). However, the differences between the groups were not significant (p > 0.05).

Inferior turbinate ablation combined with septoplasty does not provide any more benefit to the objective and subjective outcomes of patients than septoplasty alone.

This study aimed to compare the effectiveness of pharmacological therapy with and without direct maxillary sinus saline irrigation for the management of chronic rhinosinusitis without polyps.

In this prospective randomised controlled trial, 39 non-operated patients were randomly assigned to be treated with direct maxillary sinus saline irrigation in conjunction with systemic antibiotics and topical sprays (n = 24) or with pharmacological therapy alone (n = 15). Endoscopy, Sino-Nasal Outcome Test and Lund–MacKay computed tomography scores were obtained before, six weeks after and one to two years after treatment.

Post-treatment Lund–Mackay computed tomography scores were significantly improved in both cohorts, with no inter-cohort difference identified. Post-treatment nasal endoscopy scores were significantly improved in the study group but were similar to those measured in the control group. The Sino-Nasal Outcome Test-20 results showed improvement in both cohorts, with no difference between treatment arms.

Maxillary sinus puncture and irrigation with saline, combined with pharmacological treatment improves endoscopic findings in patients with chronic rhinosinusitis without polyps, but has no beneficial effect on symptoms and imaging findings over conservative treatment alone.