There is an increasingly pressing need, by several applications in diverse domains, for developing techniques able to manage and analyze very large collections of sequences, or data series. Examples of such applications come from various monitoring applications, including in power utility companies, where we need to apply machine learning techniques for knowledge extraction. It is not unusual for these applications to involve numbers of data series in the order of hundreds of millions to billions, which are often times not analyzed in their full detail due to their sheer size. However, no existing data management solution can offer native support for sequences and the corresponding operators necessary for complex analytics.