Cause and Correlation in BiologyPublished online by Cambridge University Press: 18 July 2026
Previous chapters have dealt with inferential statistical tests; that is, you have a hypothesized causal model and want to know if the empirical data could reasonably have been generated from it. This chapter deals with the converse question: given the empirical data, what types of causal graphs could have generated it? This leads to exploratory methods of SEM. After explaining how to generate new hypotheses based on an original, but rejected, causal graph, this chapter explains two algorithms based on d-separation that do not require any pre-existing causal hypothesis: the causal inference algorithm and the vanishing tetrad algorithm. These are included in the pwSEM package.
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