Anti-love drugs could easily be misused. They bring to mind disturbing parallels with sexual orientation conversion therapies and other attempts to coercively intervene in the biology of vulnerable minorities, such as LGBTQ children and adolescents. This chapter explores the dangers of making certain biotechnologies available under oppressive conditions or in societies characterized by widespread intolerance or injustice. It also questions the logic of the ‘born this way’ movement for LGBTQ rights, which is premised on the idea that sexual orientation is not a choice. If high-tech conversion therapies are ever developed that can in fact change sexual orientation, the intellectual foundation for the movement would collapse. The chapter therefore argues for the movement to be placed on stronger footing, and suggests how this might be done.