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  • Publisher:
    Wits University Press
    Publication date:
    04 June 2019
    01 October 2008
    ISBN:
    9781868147137
    9781868144655
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    • Subjects:
    Life Sciences, Molecular Biology, Biochemistry, and Structural Biology
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    Subjects:
    Life Sciences, Molecular Biology, Biochemistry, and Structural Biology
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    Book description

    The insights following the wake of the Human Genome project are radically influencing our understanding of the molecular basis of life, health and disease. The improved accuracy and precision of clinical diagnostics is also beginning to have an impact on therapeutics in a fundamental way. This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under and postgraduate science and engineering students. It serves as an introductory text for medical registrars in virtually all specialties, and is also of value to the General Practitioner wishing to keep up to date, especially in view of the growing, internet assisted public knowledge of the field. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.

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    Contents

    Page 2 of 3

    Contents
    • Chapter 22 - Leukaemias and Lymphomas
      pp 261-270
      • By Tracey M Wiggill, MB BCh, MMed (Haematology), works as a senior haematopathologist in the Division of Molecular Medicine and Haematology, National Health Laboratory Service and University of the Witwatersrand. She runs the diagnostic immunophenotyping unit at Johannesburg Hospital and her research interests include the molecular diagnostics of haematological malignancies., Nicole S Holland, MB BCh, FCPath (Haematology) is currently employed at the Johannesburg Hospital by the NHLS and is a consultant haematologist in the Division of Molecular Medicine and Haematology at the University of the Witwatersrand., Pascale Willem, qualified as a medical doctor in Paris and specialised in human genetics (Grenobles- Marseille, France). Since 1990 she has run the Somatic Cell Genetics Unit in the Division of Molecular Medicine and Haematology, University of the Witwatersrand. She is involved in cancer research and diagnostics using both molecular genetics and cytogenetics techniques., Lindsay Earlam, MB BCh, FCPath (SA) (Haematology) is currently practising as a consultant haematologist with Lancet Laboratories. Interests include leukaemia/lymphoma immunophenotyping, the molecular pathogenesis of leukaemia and haematological disease in the South African context.
    • Chapter 25 - Immunology
      pp 289-310
      • By Wolfgang Prinz, BSc (Hons), MBA, PhD, formerly senior lecturer in the Divisions of Medical Biochemistry and Physiology, University of the Witwatersrand, is now an honorary member of staff of the Division of Molecular Medicine and Haematology. His main research interest is monoclonal antibodies., Mieneke Smit van Dixhoorn, a senior lecturer in the Division of Immunology, University of the Witwatersrand. She graduated from Leiden University in 1998 with a PhD in experimental IgA nephropathy and her post-doctoral work has focused on gene expression in xeno-transplantation, resulting in 20 peer-reviewed publications. She is a former Friedland Fellow., Elizabeth Mayne, MB BCh is currently a registrar in the Division of Molecular Medicine and Haematology but knows secretly that all medicine is really just about immunology. In her spare time, she studies the history of the Ancient Near East and Psychology., Ahmed A Wadee, obtained his BSc (Hons) at the University of Toronto and has both masters and PhD degrees from the University of the Witwatersrand.
    • Chapter 27 - Tuberculosis
      pp 325-338
      • By Gerrit Coetzee, MB ChB, MSc (Medical Microbiology), MMed, heads the National Tuberculosis Reference Laboratory (National Institute for Communicable Diseases) in the National Health Laboratory Service., Hendrik J Koornhof, MB ChB, DCP (Lond), Dip Bact (Lond), FRCPath, DSc (Hon), Emeritus Professor and Honorary Professorial Research Fellow, University of the Witwatersrand, is currently Senior Pathologist, Epidemiology Division and National Tuberculosis Reference Laboratory, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg. He has been awarded the Gold Medal from the South African Microbiology Society.
    • Chapter 36 - Gene Therapy
      pp 413-421
      • By Marc S Weinberg, PhD, is a senior lecturer in the Division of Molecular Medicine and Haematology, University of the Witwatersrand, and a member of the Antiviral Gene Therapy Research Unit., Patrick Arbuthnot, MB BCh, BSc (Hons), PhD, is a reader in the Division of Molecular Medicine and Haematology at the Medical School of the University of the Witwatersrand, Johannesburg. He has a research interest in using nucleic acid transfer to develop new approaches to treating viral infections of South African importance.
    • Chapter 38 - Pharmacogenetics
      pp 433-437
      • By Chrisna Durandt, PhD, obtained her doctorate in medical immunology from the University of Pretoria in 2001 and from 2006 to 2007 was a post-doctoral fellow in the Department of Molecular Medicine, University of Pretoria, under the leadership of Professor Michael Pepper., Sahle M Asfaha, BSc, BSc (Hons), MSc, studied CYP450 pharmacogenetics from 2006 to 2007 (PhD candidate) in the Department of Immunology, Faculty of Health Sciences, University of Pretoria, and was a graduate assistant in the Department of Biology, University of Asmara, from 1999 to 2002., Michael S Pepper, MB ChB, PhD (Geneva), MD (Geneva), is Managing Director, Netcare Institute of Cellular and Molecular Medicine, Extraordinary Professor, Department of Immunology, Faculty of Health Sciences, University of Pretoria, and Professeur Associé, Department of Genetic Medicine and Development, Faculty of Medicine at the University of Geneva, Switzerland.

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