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Chapter 8 - Treatment Goals

Published online by Cambridge University Press:  10 February 2021

Carlos A. Perez
Affiliation:
University of Texas, Houston
Andrew Smith
Affiliation:
OhioHealth Riverside Methodist Hospital in Columbus, Ohio, USA
Flavia Nelson
Affiliation:
University of Minnesota, Minneapolis
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Summary

The goals of treatment in multiple sclerosis (MS) have evolved greatly over the past few decades. The original natural history of MS cohorts described in Olmsted County, Minnesota, and in Lyon, France, suggested that MS patients became disabled around the same age regardless of treatment.1,2 Therefore, even after the development of disease-modifying therapies (DMTs), the concept of medical futility remained in the field.

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