Rash

doi:10.1017/9781009500760.045

Chapter 45 - Rash

Published online by Cambridge University Press: 24 April 2026

Mallory White and

Angela Lindsay

Edited by

Angela Bray Lindsay and

Monica Kathleen Wattana

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Angela Bray Lindsay: Affiliation:
Virginia Commonwealth University
Monica Kathleen Wattana: Affiliation:
University of Texas, MD Anderson Cancer Center

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Summary

1. Engraftment syndrome (ES) is a common complication of HSCT.

2. ES is characterized by a constellation of symptoms, including fever, rash, and pulmonary infiltrates, which occur around the time of neutrophil recovery.

3. Prompt recognition and treatment with corticosteroids are essential to mitigate the cytokine inflammatory response.

4. The differential diagnosis of ES should consider infections and acute graft-versus-host disease (GVHD), requiring careful clinical assessment.

5. Distinguishing features of ES from GVHD include early time of presentation, fluid retention and pulmonary edema.

Keywords

Engraftment syndrome Oncologic Emergency Rash Bone Marrow Transplant Complication Malignant Melanoma Hematopoietic Stem Cell Transplant Complication Oncology

Information

Type: Chapter
Information: Oncologic Emergency Medicine
Clinical Cases Illustrating Key Concepts
, pp. 238 - 241
DOI: https://doi.org/10.1017/9781009500760.045 [Opens in a new window]
Publisher: Cambridge University Press
Print publication year: 2026

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