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Chapter 4 - Ectopic Pregnancy

from Part I - ANTEPARTUM

Published online by Cambridge University Press:  07 May 2010

John Patrick O'Grady ,
Martin L. Gimovsky ,
Lucy A. Bayer-Zwirello  and
Kevin Giordano
By
Samantha F. Butts  and
David B. Seifer
John Patrick O'Grady
Affiliation:
Tufts University, Massachusetts
Samantha F. Butts
Affiliation:
Assistant Professor, Department of Obstetrics and Gynecology Division of Infant and Reproductive Endocrinology University of Pennsylvania Medical School Philadelphia, Pennsylvania
David B. Seifer
Affiliation:
Professor, Department of Obstetrics, Gynecology, and Reproductive Sciences Mount Sinai School of Medicine New York
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Summary

This chapter provides a comprehensive discussion of the contemporary approach to ectopic pregnancy. It reviews the diagnosis and treatment options and the epidemiology and pathophysiology of ectopic pregnancy. Abnormalities of tubal function and ovum quality or an altered hormonal milieu may each contribute to the development of an ectopic pregnancy. Some of the most significant risk factors for the development of ectopic pregnancy include history of pelvic inflammatory disease (PID), prior fallopian tube surgery, increasing age, and a history of infertility. Prior tubal surgery results in an increased risk of ectopic implantation. Although surgery remains the mainstay of treatment for ectopic pregnancy, medical management is a widely used alternative. Methotrexate therapy for ectopic pregnancy is a widely used medical alternative to surgery. The use of proteomics to aid in the detection of early ectopic pregnancy is an active area of research.

Keywords

ectopic pregnancyfallopian tube surgerymedical managementmethotrexate therapypelvic inflammatory disease

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Operative Obstetrics , pp. 69 - 88
Publisher: Cambridge University Press
Print publication year: 2008

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