Medical students’ well-being is a concern that drawn interest.On March, 2020, WHO declared COVID-19 as a pandemic.Strict isolation measures and closing schools expected to influence the mental health of students.Online education introduced to adjust to new realities.These un-precedented circumstances create significant stress and challenges may lead to unfavorable effects on learning and the overall psychological health of students.

To explore the perception of stress and anxiety level among medical students in Saudi Arabia. To determine factors influencing perception of stress and anxiety among medical students in Saudi Arabia. To explore the association between perception of stress, anxiety and on-line learning.

An online survey will be distributed through students representatives targeting medical students from different levels. The survey will have 4 components: 1) Demographic data that will include: age, gender, level of education and region of residence. 2) Questions concerned the experience of online learning. 3) Perceived stress scale by sheldon cohen. The perceived stress scale (PSS) is a 10-question tool will be used to measure a person’s perception of stress over the past month and scored as low, moderate and high perceived stress. 4)Generalized Anxiety Disorder 7 (GAD-7) which is also a valid tool in detecting anxiety in the last two weeks by 7 items with Likert scale answers which scored as minimal, mild, moderate and severe

Currently under analysis

To be attached later

No significant relationships.

It has been previously reported that a substantial proportion of newly referred

neurology outpatients have symptoms that are unexplained by disease. There has however been controversy about how often such patients subsequently develop a disease diagnosis that, with hindsight, explains these symptoms. Our aim was to determine in a large sample of new neurology outpatients: (a) what proportion had symptoms unexplained by disease and their diagnoses; (b) how often a neurological disorder emerged which with hindsight explained the original symptoms.

The Scottish Neurological Symptom Study (SNSS) An 18 month prospective cohort study.

Secondary care NHS neurology clinics throughout Scotland UK

3781 primary care patients referred to neurology outpatient clinic (91% of those eligible).

1) The proportion assessed by the neurologists as having symptoms ‘not at all’ or only ‘somewhat explained’ by organic disease and the neurological diagnoses in these patients, 2) The frequency of an unexpected new diagnosis at 18 months which with hindsight, may have explained the original symptoms (according to the primary care physician, neurologist and consensus rating).

1144 patients (30%) were rated as having symptoms unexplained by organic disease.The most common categories of diagnosis in this group were: (a) organic neurological disease but with symptoms unexplained by it (26%); (b) headache disorders (26%) and (c) conversion symptoms (motor, sensory or non-epileptic attacks) (18%). At follow up, (mean 19 months), only 4/1030 patients (0.4%) had an organic disease diagnosis that was unexpected at initial assessment and plausibly the cause of the patients’ original symptoms. Eight patients had died at follow up; five with initial diagnoses of non-epileptic attacks.

One third of new neurology outpatients have symptoms that are unexplained by organic disease. Such patients rarely develop a new organic disease that could explain their original symptoms.

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe cutaneous drug reaction characterised by both systemic and cutaneous clinical manifestation with a mean latency period of 3.9 weeks.

To underline the importance of an early diagnosis of DRESS SYNDROME.

We reported a case of carbamazepine induced DRESS syndrome with atypical chronology of manifestations.

A 43-year-old man with no previous known medical history was admitted in psychiatry. He experienced a relapse of schizoaffective symptoms. In the last three years, the patient was treated by Valproic acid as a mood stabilizer. Because of the unavailability of this molecule, carbamazepine was prescribed in combination with antipsychotics. Three days later, the patient developed a high fever, hypotension, a pruritus, a facial oedema, a skin rash associated to lymphadenopathy. Laboratory findings showed a lymphopenia, eosinophilia and elevated liver chemistries. In order to define the case, RegiSCAR scoring system was used, and our case is categorized as probable with a score of five. Carbamazepine was discontinued upon clinical manifestationsand the patient was treated with systemic antihistaminic treatment associated to methylprednisolone with a good outcome. After 3 weeks, clinical and biological improvement were noted.

Despite the absence of a delayed onset, typically between 3 weeks and 3months, we can diagnose dress syndrome 3 days after carbamazepine intake. This case highlights that psychiatrists should be aware of the risk of early onset dress syndrome associated with carbamazepine and they should monitor for warning symptoms from treatment initiation.

No significant relationships.

Anorexia nervosa (AN) is the most severe in terms of morbidity psychiatric illness with the highest mortality rate increased by 23 fold. Treatments are limited effectiveness. AN has a strong genetic component with heritability at 70% but despite ∼ 200 studies no major gene was identified. Epigenetics, such as DNA methylation, is another component of heritability that could explain the high heritability. Methylation is poorly studied in AN from small samples, and is focused on few candidate genes among publications. Under publication, a first genome-wide methylation study investigated 10 restrictive type AN patients, 19 binging/purging type of AN patients and 15 normal eaters using DNAs from whole blood (Booij, 2015). Of the 480K CpG sites that can be methylated of Infinium Human Methylation450 BeadChip Kit, authors focused on 24,000 sites located close to genes and they identified candidate genes with a different profile of methylation between AN and controls.

Our work is to replicate the results of Booji and also to investigate the AN remitters.

Our goal is to identify epigenetic signatures of the AN disorder and the prognostic of remission.

Twenty-four AN patients, 24 AN remitters will be compared to 48 healthy control women for methylation using the Infinium Human Methylation450.

As Booji et al., we will compare methylation for 24,000 sites located close to genes for 24 AN, 24 remitters and 48 controls.

We expected to replicate the published results of Booji and to identify genes with a methylation signature specific of the AN remission.

The authors have not supplied their declaration of competing interest.

Religious and spiritual beliefs are widely recognized as important components of human wellness, of health care outcomes and of holistic medical and nursing care. There are controversial data suggesting a correlation between religiosity and mental health disorders among young adults and students. Aim of the study was to determine the association between self-esteem, depression and religious and spiritual beliefs among nursing students in Thessaloniki, Greece.

A total of 122 students agreed to participate in the study. Data was collected using the Greek versions of three self-administered, structured, pre-tested questionnaires: I) The Royal Free Interview for Religious and Spiritual Beliefs II) Beck Depression Inventory (BDI-II) and III) Rosenberg self-esteem scale.

Self-esteem was found normal in 89,3% of the students, low in 10,7%, but it is important to notice that nobody reported high self-esteem levels. The vast majority of the students (61,5%) reported both religious and spiritual beliefs. 27% reported only religious beliefs and 9% only spiritual beliefs. 31,9% of the students perceived depressive symptoms, most of them in mild levels (19,5%). Praying, religious reading and religious attendance were associated with normal self-esteem and low depressive symptoms. However, a consistent negative correlation was found between intrinsic religiosity and depression.

These findings indicate that religious and spiritual variables influence the psychological well-being of students. Religiosity may have a protective role against depression; however, our study sample is relative small and further studies are required in order to evaluate the effect of religious beliefs on the mental health of students.

The COVID‑19 pandemic has raised multiple psychological challenges among most healthcare workers, from anxiety to depression, burnout, sleep disorders, and substance use disorders. Thus, the burden caused by this prolonged medical crisis has inevitably drastically lowered the quality of life of the medical staff. In order to mitigate the negative effects of the pandemic, healthcare workers resorted to various coping strategies, with better or worse outcomes.

The present study aims to identify Romanian physicians’ main coping mechanisms and evaluate the role of positive and negative stress-reducing strategies on quality of life.

A cross‑sectional national survey was conducted using a web-based questionnaire among physicians practicing in Romania (n=265). In addition to socio-demographic and professional information, the questionnaire addressed participants’ coping mechanisms using the COPE inventory and quality of life with the WHOQOL-Brief scale. Descriptive statistics, Pearson correlations, and multiple linear regressions were used in the statistical analysis.

In total, 265 physicians consented to their participation in the survey. Of those who responded, 84.5% identified as female, 92.1% had a permanent residence in a urban setting, 63.8% were married and 55.1% attained a master’s degree, a PhD diploma or equivalent level of education. The results showed that optimism was higher in male professionals, while avoidance coping was higher in female health professionals. The mean values of QoL subscales were: 74.7± 18.3 for the general quality of life, 70.8± 20.7 for health satisfaction, 64.0± 14.2 for the physical area, 61.7± 16.2 for the psychological area, 61.2± 20.3 for the social relationships area and 64.7± 12.7 for the environment area. Specific coping mechanisms (emotional venting, behavioral and mental disengagement) were associated with lower quality of life. In contrast, emotion-focused (positive reinterpretation and acceptance), problem-focused strategies (planning, active coping, suppression of competing activities) and humor were associated positively with most QoL subscales scores.

Our data points to specific protective characteristics and some detrimental factors on physicians’ quality of life during the pandemic, with the implication that these factors may be important considerations for mitigating distress and psychiatric disorders for healthcare workers during times of high stress. Concerted initiatives to improve wellness in healthcare workers ought to develop targeted programs to ensure adequate psychological support.

None Declared

Alexithymia represents a personality construct, characterized by an inability in identifying and verbally describing own and others’ emotions. According to the recent research on emotional dysregulation and the alexithymic construct, it has been described a positive correlation between alcoholism and alexithymia. The present study aims to evaluate the presence of alexithymia in a sample of alcohol dependant patients and, therefore, analyze how the presence of these alexithymic traits may influence/interact with a range of cognitive processes such as the anger rumination, metacognitive capabilities and dissociative experiences.

A sample of 40 alcohol dependant inpatients affected with alcohol dependence and alcohol-related issues were recruited, evaluated and compared with a sample of 40 healthy controls. A clinical evaluation and a complete clinical and psychological assessment were carried out in order to investigate alcohol-related clinical patterns, alexithymia construct, anxiety and depression symptomatology and cognitive pattern.

Subjects with alcohol addiction show higher total scores in all tests except the scale that evaluates anxiety, compared to healthy controls. Finally, a factorial ANOVA analysis demonstrated that alcoholism seems to be determined by the lack of emotional recognition from which derives a dissociative state, which consequently generates a depressive rumination.

According to the recent literature, the present study identifies a significant proportion of alexithymic patients within the sample of subjects affected by alcohol-related disorders. Other clinical variables (i.e. depression, pathological anxiety-related worry, anger rumination, dissociation and metacognitive capabilities) mirror a specific cognitive pattern in the sample of alcoholics rather than the healthy group.

The authors have not supplied their declaration of competing interest.

In psychiatric practice, the assessment of change from pre- to post-treatment is a key approach for monitoring treatment effects and for the prediction of treatment outcomes. The Health of the Nation Outcome Scales (HoNOS) as a clinician-rated measure and the Brief Symptom Inventory (BSI) as a self-report measure are tools (that are) often incorporated in outcome monitoring. Their usefulness, however, has been questioned by two important issues: their psychometric properties and their lack of concordance.

The aim of the study is to evaluate the responsiveness of HoNOS and BSI as well as their interactions to predict clinical meaningful change according to the Global Clinical Impression (CGI) as quasi-gold standard for treatment outcome.

A consecutive sample of patients admitted to a Swiss psychiatric hospital for either alcohol use disorders, schizophrenic psychoses, mood disorders, anxiety and somatoform disorders, or personality disorders was assessed with Brief Symptom Inventory (BSI) at admission and discharge. The HoNOS and the CGI were rated by the responsible clinicians at admission and discharge. Ordinal logistic regressions will be conducted using the CGI categories as ordered categorical outcome. HoNOS and BSI scores as well as their interaction terms will be used as independent variables.

Complete data of admission and discharge is available from approximately 600 cases. Graphical presentations will illustrate the resulting associations.

The authors have not supplied their declaration of competing interest.

Cognitive complaints and psychological distress are common in oncologic patients, in particular many studies have focused on women with breast cancer.Patients presenting the phenomenon of “chemofog” show changes after chemotherapy with regard to memory and emotional regulaiton.

To explore brain connectivity prior to chemotherapy that nevertheless,is understudied.

We used fMRI to investigate the resting state connectivity in 24 patients before chemotherapy and 15 controls.Patients were assessed with self-administered questionnaires,such as the Patient’s Assessment of Own Functioning Inventory (PAOFI) that quantifies the decrease in perceived functioning in memory, language and problem solving (Image 1).We used a preliminary structural analysis in order to choose which neuropsychological test was affected in correlation with a significant anatomical volume alteration,as showed in the p-value table.Therefore, patients were ranked and divided into two group of “Impaired vs Preserved”, measured using the median of the questionnaire results.Higher scores indicate a poor cognitive self-perceived performance.

Connectivity was altered in amygdala and hippocampus, in the subgroup of patients with higher subjective cognitive complaints i.e with a high PAOFI Memory score.More specifically, we found an association between memory impairment and the increase of the resting state connectivity of both right structures, as opposed to a reduction in left amygdala (Image 3).

These findings may suggest a potential effect on brain functional connectivity of the psychological awareness and stress of cancer itself. We found connectivity alterations for both amygdala and hippocampus, two structures belonging to the limbic system, that is involved in the interplay between cognition and emotions, such as anxiety and fear.

Maladaptive defense mechanisms can play a role in maintaining the inadequate social and psychological adaptation of patients.

This study aims to establish if denial is one of the central psychological defense mechanisms in patients with somatoform disorder.

10 female patients at Moscow Clinical hospital №33 with somatoform disorder and panic attacks (aged 20 to 43) and 20 female participants of the control group (aged 19 to 35) were presented with 10 pictures of the Thematic Apperception Test. Pictures were previously annotated into 4 groups: neutral stimuli (2, 6GF), provoking self-blame / depression ideation stimuli (3GF,14, 15, 17GF), provoking aggression ideation stimuli (8ВМ, 18 GF, 9GF), provoking aggression/self-blame ideation stimuli (13 MF). We conducted content analyses of stories. Mann-Whitney U-test was used.

Table 1 presents analyses categories, examples of stories, and group differences.Table 1

Patients with the somatoform disorder tended to use descriptions without interpersonal or internal conflicts and/or to deny any characters‘ negative intentions or the negative consequences of their actions.

No significant relationships.

Clinical reality presents us with a series of continua in the area of mood disorders: those between 'normal” sadness and depression, between 'normal” elation and hypomania, between a 'pure” depressive episode and a 'pure” manic episode, between unipolar depression and bipolar disorder, between anxiety disorders and depression, and between mood disorders and psychotic disorders. Most of our classificatory efforts and controversies in this area center around how to deal with these continua, where to fix boundaries and how to delineate intermediate or mixed conditions. In this presentation, I briefly review the expected convergences and divergences between the ICD-11 and the DSM-5 in handling these continua, and the research evidence supporting the proposals made for the ICD-11. Among the convergences are the inclusion of activation/increased energy as a defining symptom for hypomania/mania, and the acknowledgement that a manic/hypomanic syndrome emerging during antidepressant treatment, and persisting beyond the physiological effect of that treatment, qualifies for the diagnosis of manic/hypomanic episode. Furthermore, bipolar II disorder will be recognized as a distinct diagnostic entity in the ICD-11, as in the DSM-5, while in ICD-10 it is just mentioned among 'other bipolar affective disorders”. Finally, the ICD-11, as the DSM-5, will allow the clinician to record the occurrence of prominent anxiety symptoms in a patient with a major depressive episode, by using a specifier. Expected divergences between the ICD-11 and the DSM-5 will include a different characterization of mixed states and schizoaffective disorders. Furthermore, the ICD-11 is going to exclude from the diagnosis of depressive episode, in line with the ICD-10 but differently from the DSM-5, bereavement reactions appropriate to the individual's cultural and religious background.

One of the defining features of autism spectrum disorder (ASD) are deficits in social interaction and communication. Although their etiology is poorly understood, several lines of evidence from studies on humans and rodents suggest that two nonapeptides – oxytocin and vasopressin – might play a pivotal role in their development.

To evaluate if single nucleotide polimorphisms in OXTR and AVPR1A genes are linked to the severity of symptoms in autism spectrum disorder.

The study was conducted on the group of 40 Caucasian males with average age of 14,22 (SD: 1,71) years. ADOS-2 examination was utilized for confirmation of ASD diagnosis as well as evaluation of symptoms severity in each patient. The genotyping of preselected SNPs for each gene (rs10877969; rs7294536; rs2254298; rs53576) was conducted.

“CC” genotype at rs7294536 (p=0,033) was significantly associated with higher outcomes of ADOS-2 especially in terms of social affect. In case of oxytocin receptor gene, frequency of “AA”/”AG” genotype at rs2254298 equaled 100% and of “AA”/”AG” genotype at rs53576 equaled 85% of the study group (expected “A” allele frequency in neurotypical European population was respectively 11% and 35% according to 1000Genomes database). For rs10877969 prevalence of “CC”/”CT” genotype equaled 95% while expected frequency of “C” allele in neurotypical European population was 13%.

Overrepresentation of minor alleles at rs2254298, rs53576 and rs10877969 in patients with ASD might indicate their link to development of ASD. Furthermore, significant association between minor allele at rs7294536 and symptoms severity suggest potential role of arginine-vasopressin receptor deficiency in clinical picture of ASD.

No significant relationships.

The purpose of this study was to assess the factors that influence attitudes of people neighbouring to residential care facilities that host chronic psychiatric patients formerly hospitalized in a psychiatric hospital, 2 years after their deinstitutionalization.

One member of at least 30 households neighbouring to 8 community-based psychiatric facilities (hostels and sheltered apartments) was interviewed by a group of specially trained social workers. The structured interview used was compiled specifically for the needs of this study.

Less than 25% of our sample had adequate knowledge of the term ‘deinstitutionalization’ and in particular people with higher education and that have been visited by a psychiatric resident. Nevertheless, their attitudes were in general positive. In a regression analysis, attitude towards deinstitutionalization was found to be positively correlated with having visited a psychiatric facility, years of education, and living near 4 out of the 8 psychiatric hostels [R-squared=0.20]. Female neighbours were generally more favourable, but this effect was only marginally significant. Attitude towards the psychiatric patient was best predicted by years of education, having visited a psychiatric hostel and living near 2 out of the 8 psychiatric hostels [R-squared=.21]. Age was generally negatively correlated with attitudes towards the patient [r=-0.23]. There were also significant differences among the attitudes of the various hostel neighbourhoods.

Apart from education, age, and gender the most important factors in influencing attitudes towards deinstitutionalization and patients are local. Choice of favourable locations for psychiatric facilities and cultivation of a positive neighbourhood climate are important.

Violence is recognised by the WHO as a major and ubiquitous public health problem, that is constantly worsening.

The aim of our work was to estimate the frequency of aggressions against nurses in psychiatric and emergency departments, and to identify the factors associated with it.

This was a cross-sectional, descriptive and analytical study. It took place between January and March 2021, at both hospitals of Sfax (Tunisia).This study targeted 60 nurses in the psychiatry and emergency services.

The sample comprises 35 nurses (58%) from psychiatric services and 25 nurses (42%) from emergency services, mainly females (51%) and with average age of 35 years.(+/-9). The nurses interviewed were exposed to violence quite often, in 93% of cases. Almost all nurses (90 %) experienced verbal violence, 70 % experienced physical violence and more than half (62 %) experienced psychological violence. Nearly 11% of nurses reported a sexual violence. Factors that explain or contribute to violence mentioned by the participants were as follows; The Verbal violence was significantly correlated with poor reception conditions (p=0.013). The Sexual violence was significantly correlated with young age of nurse (p=0.005). As for psychological violence, it was significantly correlated with work overload (p=0.004), a poor caregiver-patient relationship (p=0.02) and poor patient care (p=0.04).

Our study showed that violence against nurses was frequent in psychiatric and emergency departments. Various factors could modulate their occurrence such as training and improvement of the working conditions.

No significant relationships.

To estimate the prevalence of suicidal ideation during gestation and risk factors for depression in postpartum.

712 pregnant women answered the PRIME MD, and reported sociodemographic data, obstetric history and history of violence; 427 women answered the PRIME MD at 4-5th month postpartum. Poisson regression was used to estimate the association between suicidal ideation and sociodemographic, obstetric and violence variables, and to estimate the association between risk factors and depressive symptoms in postpartum.

The prevalence of suicidal ideation during pregnancy was 10.3% (n=73). The prevalence of depression was 36.2% (n=258). Suicidal ideation was associated with: 0 to 4 years of schooling (PR=2.88, CI 95% 1.40-5.91), and 5 to 8 years of schooling (PR=2.63, CI 95% 1.45-4.77), being victim of violence in the current gestation (PR=4.35, CI 95% 2.81-6.74), and anxiety symptoms (PR= 5.49, CI 95% 3.58-8.40).

The prevalence of depression in the postpartum was 28.3% (n=121); 45 were incident cases (37%). The following variables were significantly associated with depression in postpartum: < 19 years of age (RR=1.82, CI 95% 1.03-3.22), 20-29 years of age (RR=2.19, CI 95% 1.30-3.66), lower income (RR= 1.49, CI 95% 1.00-2.23), depressive symptoms during gestation (RR=2.9, CI 95% 2.13- 3.97), anxiety symptoms during gestation (RR= 2.96, CI 95% 2.26-3.88), and being victim of violence during gestation (RR=2.04, CI95% 1.50-2.78).

Gestation is not protective of suicidal ideation and common mental disorders. Treating common mental disorders during pregnancy is essential to prevent depression in post partum and to promote maternal's and infant's health.

Examine impact of audit and feedback on antipsychotic prescribing in schizophrenia over 4.5-years.

Clinical files in three outpatient psychiatric services in Auckland, New Zealand were reviewed at two time-points (March-2000;October-2004). After the first audit, feedback was provided to all three services. Baseline prescribing variations between services were found for antipsychotic combinations and atypical prescribing, in particular clozapine. In two services audit and feedback continued with two interim reviews (October-2001;March-2003). Specific feedback and interventions targeting clozapine use were introduced in both services. No further audit or feedback occurred in the third service until the final audit. Data were collected (patient characteristics, diagnosis, antipsychotic treatment) and analysed at each audit.

Three prescribing variables (antipsychotic monotherapy, atypical and clozapine use) were consistent with practice recommendations at the final audit (85.7%, 82.7% and 34.5% respectively) and had changed in the desired direction for all three services over 4.5-years. At baseline there were differences between the three services. One service had baseline prescribing variables closest to recommendations, was actively involved in audit, and improved further. The second service, also actively involved in audit had baseline prescribing variables further from recommendations but improved the most. The service not involved in continuing audit and feedback made smaller changes, and atypical and clozapine use at endpoint were significantly lower despite at baseline being comparable to the service which improved the most.

We found high intensity audit and feedback was an effective intervention in closing the gap between recommended and clinical practice for antipsychotic prescribing.

Chronic hepatitis C virus (HCV) infection is a disease that afflicts more than 170 million people worldwide and is a major cause of liver disease, cirrhosis, and hepatocellular carcinoma. Standard pharmacologic treatment for HCV infection is the antiviral combination of pe-gylated interferon (IFN) and ribavirin (RBV). Several psychiatric side effects such as depression, anxiety and even psychosis and cognitive impairment were reported.

To review the neuropsychiatric side effects of interferon treatment of HCV infection though the study of a case report.

We present a case of a 45-years-old without personal or familiar psychiatric history, admitted in our inpatient unit with psychotic symptoms during the last 2 weeks, consisting of paranoid delusions and aggressive and bizarre behavior. The patient had history of HCV and HIV infection and had initiated treatment with pegylated IFN alpha e RBV in the prior 6 months. Neuroimaging and laboratory tests were done without significant alterations. He was treated with Olanzapine 15 mg od with improvement of the psychotic symptoms and without important side effects. At the time of hospital discharge, psychotic symptoms had almost disappeared and no behavioral disorder was observed.

IFN-associated psychiatric disorders appear to be much more common than previously thought. The increased in pro-inflammatory cytokines in certain psychiatric disorders was widely reported. We believe that the inflammatory setting may be considered as an important further piece in the puzzle in a genetic-environmental diathesis model of the psychiatric diseases.

Electroconvulsive therapy is widely used for treatment-resistant psychiatric patients. There is controversy about the minimum seizure duration required for clinical efficacy.

Characterize socio-demographically the electroconvulsive therapy unit of CHPL; find a correlation between improvement on PSAS, PANSS and HAM-D and both mean seizure duration and mean electric charge used; evaluate outcome in patients with seizure < 20s.

Three groups of patients were created according to ICD-10 diagnosis. The scales mentioned were applied at the beginning and end of the treatment: depressed (F31.3-5; F33; F20.4; F25.1) - HAM-D; schizophrenic/ schizoaffective/ bipolar-manic or mixed (F20.X, F25.X, F31.0, F31.6) - PANSS; with any of these diagnosis: PSAS. The correlation between the improvement on each scale and both mean seizure time and mean electric charge was investigated using the Pearson product-moment correlation coefficient. The groups were subdivided by seizure duration (cut-off 20s) and the mean improvement on the different scales was determined for each subgroup.

There is no correlation between any of the variables analyzed (α = 0,05). HAM-D variation (N = 102): seizure duration (r = 0,004) and electric charge (r = 0,106). PANSS variation (N = 43): seizure duration (r = 0,07) and electric charge (r = 0,046). PSAS variation (N = 147): seizure duration (r = −0,043) and electric charge (r = 0,143). There is no difference statistically significant in mean HAM-D, PANSS or PSAS improvement between subgroups >20s and < 20s (11.29 vs 13.94; 30.85 vs 29.19 and 19.07 vs 22.65, respectively).

Mean seizure duration and electric charge didn’t correlate with clinical outcome. Seizure duration below 20 seconds didn’t imply poorer outcome.

Adults may continue suffering AHDH symptoms after this condition is recognized and typified in children. Different works provide evidence that adults have an even more complicated variety of psychiatric disorders than children, as an increased risk of problems stemming from substance abuse, depression, anxiety, increased risk of traffic accidents, and also sexual transmission diseases.

There was known that adults could continue suffering symptoms derived from his infantile ADHD. We wonder if the majority of the young males derived to our consultation present compatible symptoms with adult ADHD. This condition promotes the onset of substance use and may lead to latent psychosis onset.

We analyzed 39 patients derived by suspicion of psychiatric pathology, aged between 17 and 35. They stem to clinical psychology for study of features of personality (Million Questionnaire). Another questionnaire was used also autoapplied for sifted of the ADHD in adults (ASRS_V1:1). According to the criteria DSM-IV TR, the patient had moderate symptoms of ADHD if it was fulfilling 6 or more diagnostic criteria according to their answers in the screening questionnaire.

The results supported the existence of impulsivity, aggression, irritability, problems with compliance and substance abuse.

ADHD is not only a problem of distractibility or worry, but a deeper and extensive alteration caused by the deterioration of a set of cerebral activities. An early treatment in the childhood could prevent devastating consequences for their development, since they include the majority of the functional areas of the patient and it impedes their later social and labor adjustment.

No significant relationships.