The anti-convulsant value of sodium diphenyl hydantoinate (S.D.H.), marketed in America as Dilantin and in England as Epanutin, as found by Putnam and Merritt and introduced by them in the treatment of epilepsy has been amply confirmed by all subsequent reports, as it is by this one. Its clinical application, however, will, it is thought, be modified by reason of its toxic nature becoming more generally known.