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Chapter 8 explores how national governments can help multinational corporations seize emerging opportunities in the low-carbon transition. Building on the prior chapter’s discussion of governance and planning, capacity building, and incentives and regulations, the chapter examines how public policy in these domains can foster sustainable business opportunities. It highlights several specific policy instruments: climate-focused economic zones (governance and planning), green technology and innovation funds (capacity building), and public procurement and regulatory sandboxes (incentives and regulations). The chapter concludes by assessing how firms and governments can collaborate to generate mutually reinforcing climate outcomes, emphasizing public–private partnerships (PPPs) as key vehicles for innovation and risk-sharing. Case studies of Japan’s Fujisawa Sustainable Smart Town, Norway’s Northern Lights CCS project, and California’s ARCHES hydrogen alliance illustrate distinct PPP models.
Chapter 7 investigates how national governments can reduce corporate exposure to climate risks through public policy. It identifies three categories of policies that potentially reassure investors: governance and planning, which encompass national climate strategies and institutional coordination, capacity building, which includes disaster preparedness and public infrastructure for resilience, and incentives and regulations, such as environmental standards and climate-related fiscal policies. The chapter examines whether these policies moderate the negative relationship between climate vulnerability and foreign direct investment identified in Chapter 4. Using cross-national empirical analysis, it finds that in countries where these policy areas are relatively strong, investors’ concerns about climate risk are significantly mitigated. These results suggest that government-led adaptation efforts can serve as credible signals of state capacity and long-term stability, thereby strengthening confidence among multinational firms operating in or entering climate-vulnerable economies.
Humanitarian settings in Pakistan face major gaps in mental health service delivery, with limited specialist resources and a high burden of untreated conditions. Though the World Health Organization’s mhGAP-Humanitarian Intervention Guide aims to strengthen the capacity of primary care physicians to identify and manage common mental health conditions, the evidence for multidimensional training outcomes remains limited. This study evaluated the effectiveness of mhGAP-HIG training outcomes in terms of knowledge, skills, attitudes and confidence among physicians across different humanitarian contexts in Pakistan. As part of implementing an evidence-based digital MHPSS service model, seven mhGAP-HIG workshops were held across two provinces and a federal area. We conducted a quasi-experimental, mixed-methods evaluation where a total of 149 physicians completed standardized assessments of knowledge (mhGAP-HIG), therapeutic skills (ENhancing Assessment of Common Therapeutic Factors), attitudes (Mental Illness: Clinician’s Attitudes Scale-v4) and confidence, before and after the training. Paired sample t-tests and ANCOVA were used to assess within-group and between-group changes, respectively. Quantitative feedback and qualitative reflections were also evaluated. We found significant improvements across the domains of knowledge, skills, confidence and a modest improvement in attitude. The participants from Khyber Pakhtunkhwa showed greater gains in knowledge, while participants from Baltistan showed greater gains in skills, as compared to other provinces. Participants expressed a high level of satisfaction, reporting improvements in knowledge, confidence and ability to identify and manage common mental health conditions. Systematic efforts to adapt and implement mhGAP-HIG may lead to significant improvements across multidimensional competencies of physicians.
Chapter 3 delves into the material facet of China’s image-making or attraction through tangible offerings. Drawing on the analysis of China’s core diplomatic initiatives in Ethiopia, namely elite training and education diplomacy, Confucius Institutes, and media outreach, the chapter illuminates how offering access to opportunities and resources is at the heart of initiating participants into China. It also examines the uneven deployment of “tangible enticement” by demonstrating how Chinese actors, including embassy personnel and Confucius Institute directors, amongst others, are at once strategic and methodical about presenting targeted opportunities, as well as spontaneous and hands-off in promoting and allocating resources. The chapter then analyzes the reception from Ethiopian target audiences, finding a mix of opportunistic engagement and negotiation of China’s offerings.
Sustainability transitions in manufacturing require new competences and organisational learning. This paper presents Schedazioni, a learner-led assessment tool that helps companies analyse past sustainable design actions. Developed through case studies and a Research-through-Design process, and piloted in industry, it enables teams to map transformations, identify problems, and reflect on impacts. By shifting assessment to internal sensemaking, it supports shared understanding and strengthens sustainability capability.
Community Engagement and Outreach (CEO) Cores are a key component of the IDeA Clinical and Translational Research (IDeA-CTR) Program, serving to develop and implement capacity-building initiatives that empower communities to engage and collaborate with investigators in community-engaged research. To strengthen collaboration and shared learning across sites, a CEO Special Interest Group was established. In 2022, the group conducted a landscape analysis to systematically characterize and categorize CEO Core activities across the IDeA-CTR network, with a focus on capacity-building efforts related to knowledge transfer, co-learning, and infrastructure development. The analysis revealed several common approaches to community engagement and capacity building across sites, as well as distinctive strategies tailored to the specific needs and communities served. Multiple innovative practices were identified and disseminated across the network, highlighting opportunities to enhance collective impact and inform future community-engaged efforts.
Health technology assessment (HTA) is a multidisciplinary, policy-oriented process designed to inform evidence-based, transparent, and value-based decision making in health systems. Across the Middle East and North Africa (MENA), HTA development remains heterogeneous and unevenly institutionalized. This manuscript reports on a Health Technology Assessment international (HTAi)-led Policy Dialogue designed to identify shared challenges, priorities, and opportunities to strengthen HTA systems across the region.
Methods
Insights were generated through an in-person meeting held in Tunisia in 2025, alongside the HTAi MENA Regional Meeting. The dialogue was complemented by an online survey and a follow-up virtual meeting. Data sources included structured survey responses from experts across twelve countries and qualitative inputs from multi-stakeholder discussions involving policymakers, HTA practitioners, academics, and international organization representatives. Findings were synthesized descriptively to capture perceived challenges, priorities, and expectations for regional and international collaboration.
Results
Participants emphasized HTA’s role in improving resource allocation, transparency, and access to high-value technologies. Key challenges included limited access to high-quality data, workforce capacity constraints, fragmented governance, and weak legal and institutional frameworks. The highest-ranked priorities were establishing formal legal mandates for all actors involved in HTA processes, building technical and system capacity (including institutional governance, processes, and coordination mechanisms), and strengthening health data infrastructure. Strong support emerged for regional cooperation through joint training, shared assessments, and HTA networking, alongside expectations for international organizations to play a catalytic role.
Conclusions
HTA is gaining prominence across MENA, but most countries remain in early phases of institutional development. Progress will require coordinated action on governance, capacity, data systems, and implementation.
Translational science (TS) workforce development initiatives are emerging to fast-track conversion of findings into applications to improve health. Principles of TS were developed to guide workforce development; however, few tools are available to evaluate confidence related to these principles to benchmark progress.
Objective:
Our goal was to develop and validate a scale for assessing confidence related to the seven TS principles and get feedback about future workforce development opportunities that could be evaluated with this scale.
Methods:
A cross-sectional survey was conducted in 2025 engaging 158 researchers and research staff affiliated with three Clinical and Translational Science Award hubs in Alabama, Massachusetts, and Ohio. Factor analysis was conducted to determine interrelatedness among the TS principles, reliability was assessed using Cronbach’s alpha, and mixed effects models were used to examine differences in confidence levels.
Results:
Four factors emerged (α = 0.95 for full scale, 14 items), including Taking Risks for Impact (α = 0.85, 2 items), Multi-perspective Research (α = 0.88, 3 items), Collaborative Methods (α = 0.89, 6 items), and Efficiency and Productive Failure (α = 0.88, 3 items). Confidence levels varied significantly by factor (p < 0.001) with the lowest mean confidence (1 = lowest, 5 = highest) for the Efficiency and Productive Failure (2.56) and Taking Risks for Impact (2.79) factors. There were no differences in mean levels of confidence by demographics, site, or experience.
Conclusion:
Findings provide guidance for prioritizing topics for future TS workforce development initiatives as well as a brief scale for evaluating how these interventions cultivate confidence across the seven TS principles.
Despite the growing application of behavioural science in public policy, progress in many countries has been slow. This study explores the challenges in applying behavioural insights (BI) to policymaking and identifies potential solutions. We conducted semi-structured interviews with 12 behavioural science experts who have worked with national governments or international bodies across 39 countries. Using inductive content analysis, we discovered three main challenges perceived by the experts: limited knowledge and misunderstandings of BI among stakeholders, constraints within the public policy environment, and resource limitations in both BI units and public administrations. The experts also highlighted strategies to build capacity within the public sector, including creating peer networks, partnering with external experts, organising targeted training programmes, and providing supportive tools and resources. We interpret these findings through the lens of navigating complex adaptive systems, distinguishing between ordered problems – amenable to transferable solutions – and genuinely complex problems requiring participatory approaches and contextual adaptation. Advancing contextual understanding of behavioural science in policy may require distinguishing challenges that permit efficient solutions from those demanding slower, relationship-based sense-making.
Despite substantial investment in clinical and translational research, only a small proportion of evidence-based interventions are adopted and sustained in routine practice, contributing to persistent delays between discovery and population benefit. Dissemination and implementation (D&I) science is a critical discipline for addressing this gap, and the NIH Clinical and Translational Science Award (CTSA) program (established 2006) has been strategically positioned as a national infrastructure to advance D&I capacity. We conducted a national environmental scan of publicly available websites and documents from all 66 CTSA hubs (May–July 2025), using a structured extraction tool to capture D&I-specific activities across seven domains: institution and community partnerships, formal D&I organizational structures within the CTSA, consultation services, collaborative programming, training opportunities, educational offerings, and pilot funding mechanisms. Findings reveal substantial heterogeneity in D&I science activities across CTSA hubs; 45% had a formal D&I unit, 54% offered D&I consultation services, and 37% provided collaborative programming. Structured workforce development was limited: 12% offered D&I-focused training grants, 15% offered structured educational programs, and 15% provided D&I-specific pilot funding. Consultation models varied widely in scope, access, and evaluation practices. These findings demonstrate uneven development of D&I science infrastructure across CTSAs and highlight opportunities to strengthen capacity nationally.
The European Union health technology assessment (HTA) regulation increases pressure on European HTA organizations’ capacity and new domains of expertise continue to emerge quickly in the HTA field. Therefore, this study aimed to identify emerging competencies described in the literature and to update and verify an existing HTA competency framework, encompassing both process-related and domain-specific expertise for conducting HTA.
Methods
Using a scoping review approach, PubMed, Embase, PsycINFO, ERIC, CINAHL, and Web of Science were searched from 1 January 2018 until 13 May 2024. The websites of HTA-related societies were searched on 22 April 2024. Documents describing competencies for HTA professionals were included. Deductive content analysis of the identified competencies was performed, utilizing the competencies from the original framework.
Results
A total of nineteen documents were included, consisting of six competency frameworks, one handbook, and twelve scientific articles. The identified competencies from these documents mapped appropriately to the original competency framework. New competencies within existing domains that emerged were related to organizational sustainability, patient and public involvement, real-world data, interpreting and developing HTA reports, and stakeholder identification. In addition, three new competency domains were identified, which were artificial intelligence use for HTA, environmental aspects, and performance and achievements.
Conclusions
The newly identified competencies and competency domains highlight emerging areas of expertise for HTA professionals and need to be added to the original competency framework. An updated competency framework can support capacity building efforts and the development of training programs to ensure that HTA professionals are well-equipped to address current healthcare challenges.
Solar geoengineering (SG) is a set of highly controversial emerging technologies proposed to address climate change by reflecting sunlight away from the planet to reduce temperatures. SG may reduce climate risks, however it also presents novel risks, uncertainties, and challenges, necessitating broad and inclusive public engagement. This Element presents a briefing book and methods toolkit to build capacity for public engagement on SG. Part I of the Element explains the need to build capacity to enable public engagement on solar geoengineering, and presents three methods for doing so: capacity building workshops, participatory Technology Assessment, and Deliberative Polling. Part II presents a briefing book that provides accessible, balanced, and evidence-based information on critical topics including climate science, climate policy, SG science, SG governance and policy, and SG ethics and justice. This title is also available as open access on Cambridge Core.
Since its establishment in 2005, the HTAi Patient and Citizen Involvement in HTA Interest Group (PCIG) has worked to strengthen health technology assessment (HTA) by systematically incorporating patient and citizen perspectives. Over two decades, PCIG has advanced this goal through multistakeholder projects and collaborations that have produced practical tools, guidance, and methods to support patient involvement in HTA worldwide. Through global knowledge exchange, PCIG has fostered shared learning and capacity building for inclusive, participatory HTA. Its work continues to drive a shift in the mindset of the HTA community – from passive consultation to active partnership with patients and citizens – and encourages investment in robust research to understand patient perspectives. As health systems increasingly aim to reflect lived experiences and community values to improve the implementation and impact of services, PCIG’s journey offers a compelling example of the long-term value of collective action, sustained engagement, and meaningful involvement in HTA.
I will refrain from raising things I have already discussed on numerous occasions, but I want to further clarify a matter that has to do with agents.
In the past, we used to think of the term ‘agent’ as designating only (or mainly) turned elements from the antagonistic classes. It was not all-inclusive. We knew from firsthand operational experience that, in actual struggle, agents constituted covert assets employable in routine surveillance as well as in case-related operational activity. While we now allow ourselves to continue to recruit such assets from among the elements of the antagonistic classes, we should also, in the same way, proceed to recruit them from among the masses and the activists – or even from among Communist Party and Youth League members – as long as they possess the necessary qualifications. To assume that our agents may only be recruited from among the elements of the antagonistic classes, not from among our own base of masses and activists, or to maintain that only individuals from the antagonistic classes serving operational needs may be spoken of as agents (while individuals recruited from among our own base of masses and activists serving operational needs may not) is to have an incomplete understanding.
How should we proceed in merging what [in Shenyang’s economic protection sector] are currently agents, informants, and confidential guardians and in designating all of them agents?
The creation of a single uniform designation calls for identifying the specific utility of each agent, carrying out individual validations, and deciding on the level at which the agent is to be run. (Note: below, informants and confidential guardians are all referred to as agents.) Agents about whom we already have a pretty good idea are to be examined in detail; agents about whom we still really do not have a good idea must be scrutinised in depth and exhaustively, and their recent records as well as their documented pasts must be appraised repeatedly. In the end, we must produce conclusive validation reviews to determine our decisions about whether to retain or to terminate.
As Ukraine works to modernize its healthcare system and align with international standards, integrating health technology assessment (HTA) into the national decision-making process has become a strategic priority. While HTA practices for pharmaceuticals have advanced, substantial gaps persist in the evaluation of medical devices (MDs), which require distinct methodological approaches given their characteristics. This article presents the rationale, development, implementation, and results of a comprehensive online training program aimed at building national capacity in the MD assessment. The program targeted 71 Ukrainian professionals with prior experience in pharmaceutical evaluation but limited exposure to MD. Through 40 hours of live online sessions delivered from September to December 2024, the course emphasized interactive learning, contextual adaptation, and international best practices. Assessments showed significant knowledge gains, with 87 percent of participants completing the program successfully. The initiative demonstrates that targeted, competency-based training can enhance national HTA capacity and may serve as a model for other transitioning healthcare systems.
New technologies are being developed in a context of scarcity. Health technology assessment (HTA) aims to support decision makers in providing equitable and affordable access to effective innovations. This study aims to summarize the policy-related findings of a Horizon2020 project on innovating HTA methods and discuss their implications for the governance of HTA in Europe.
Methods
A thematic analysis of policy-oriented papers (n = 18) from the Next Generation Health Technology Assessment (HTx) project was carried out to summarize challenges and solutions. Subsequently, via an online survey and in a 2-day meeting, European and global stakeholders (n = 21) were invited to comment on these solutions and to prioritize future strategies.
Results
Reported challenges included a lack of access to standardized data, differences in evidentiary needs, existing policy structures, and a lack of capacity and knowledge. Suggested solutions were capacity building, national and international dialogues, standardization, and increased European collaboration. Stakeholders had different expectations with respect to the likely success of these solutions.
Conclusion
Innovation of HTA requires alignment of evidentiary needs through dialogues, standardization through increased European collaboration, and capacity building. However, without additional investments in personnel capacity, HTA agencies must still prioritize some activities at the expense of others. Furthermore, although European collaboration is important, global alignment might be required to enforce standardization.
The 2025 Evaluation Special Interest Group (SIG) meeting at the Association for Clinical and Translational Science conference brought together clinical and translational science (CTS) professionals to address evolving challenges in translational science evaluation. The meeting presentations and discussions addressed concept mapping for commonly used metrics, continuous quality improvement (CQI) practices, translational science impact evaluation, and evaluator toolkit development. Key themes and lessons learned included the tension between institution-specific and network-wide evaluation goals, the need for standardized yet flexible evaluation frameworks, and persistent barriers including limited staffing capacity and data ownership challenges. Facilitators identified included diverse CQI approaches, the evolving frameworks, and collaborative evaluation practices. Convened during a time of increasing research funding uncertainty and accountability, the meeting underscored the urgency of strengthening evaluation capacity to sustain the impact of CTS, highlighting both the enduring value of heterogeneous evaluation approaches and the critical need for coordinated CTS evaluation strategies to demonstrate impact and secure continued funding support.
In this chapter, we describe content delivery methods and lessons learned when combining the massive open online course (MOOC) with the smaller, remote version of the course offered through MIT in Fall 2020. This approach was tested when MIT school buildings were closed due to the COVID-19 pandemic, and all classes became virtual. For a broader application, we also lay out hands-on tips for sustainable design educators on how to administer a hybrid course that outsources the tutorials, lectures, and assignments from the online course while engaging students through in-person or virtual meetings for in-depth discussions and course project development.