Joyce structures are a class of geometric structures that first arose in relation to Donaldson–Thomas theory. There is a special class of examples, called class $S[A_1]$
, whose underlying manifold parameterizes Riemann surfaces of some fixed genus equipped with a meromorphic quadratic differential with poles of fixed orders. We study two Joyce structures of this type using the isomonodromic systems associated with the Painlevé II and III$_3$
equations. We give explicit formulas for the Plebański functions of these Joyce structures and compute several associated objects, including their tau functions, which we explicitly relate to the corresponding Painlevé tau functions. We show that the behavior of the Joyce structure near the zero section can be studied analytically through poles of Painlevé equations. The systematic treatment gives a blueprint for the study of more general Joyce structures associated with meromorphic quadratic differentials on the Riemann sphere.