Women entrepreneurs face distinct gender-specific challenges, including restricted access to venture capital, work–life conflicts driven by stereotypes, and competing demands from their roles as business owners, caregivers, and community leaders. These pressures often foster polychronicity – a temporal orientation favoring simultaneous task management. Grounded in role accumulation theory, we conduct a two-stage survey of 129 Chinese women entrepreneurs to investigate the relationship between polychronicity and resilience. We further examine three moderators – frequent interruptions, entrepreneurial experience, and emotional intelligence – that amplify polychronicity’ s resilience-building effects. This study highlights the positive association between polychronicity and women entrepreneurs’ resilience, offering new insights into temporal dynamics in entrepreneurship. It also provides women entrepreneurs with practical strategies to help them navigate multiple role challenges and thrive amid adversity by leveraging their preference for multitasking.