The Ulz River in north-eastern Mongolia is an important breeding habitat for the western population of White-naped Crane Antigone vipio. The destruction and degradation of wetlands, the main breeding habitat of White-naped Cranes, are the main factors affecting the population. The breeding population census of 2019–2021 in the Ulz River basin was analysed and compared with previous surveys conducted in 2001 and 2011. The surveys showed that along the Ulz River, crane pairs declined from 42 territorial pairs in 2001 around the start of the drought period to 17 territorial pairs in 2011 when the drought was still on-going and then increased to 30 territorial pairs in 2021 after the end of the drought period. Along the Ulz River, six successful breeding pairs of White-naped Crane in 2019, 11 successful breeding pairs in 2020, and 18 successful breeding pairs in 2021 were recorded. This indicated that changes in the breeding pairs and territorial pairs of the White-naped Crane along the Ulz River were influenced by rainfall, that the western population of White-naped Cranes has increased in the last three years and, in addition, will likely decrease during future dry periods. Proper management of the Ulz River wetlands is more important during the dry periods, and in this study, we aimed to estimate the breeding population of White-naped Cranes along the Ulz River, determine the factors influencing distribution and population changes, and suggest what is needed for future conservation of this species.