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This retrospective observational study aimed to identify factors and predictors associated with the need for lifelong medication after total thyroidectomy for thyroid carcinoma.
Methods
A total of 96 patients who underwent total thyroidectomy for thyroid carcinoma from July 2017 to July 2023 at a tertiary hospital were retrospectively reviewed.
Results
Among the participants, 39 (40.6 per cent) of 96 required long-term calcium and calcitriol supplementation. A smaller number of preserved parathyroid glands during surgery was significantly correlated with the necessity to continue calcium supplementation. Poorly corrected calcium levels on the first post-operative day were significantly associated with the need to continue calcitriol and/or calcium supplementation.
Conclusion
In patients undergoing total thyroidectomy for thyroid carcinoma, careful preservation of the parathyroid glands may reduce the risk of permanent calcium supplementation, whereas an early post-operative decline in serum calcium levels may help identify patients at a higher risk of requiring prolonged medication.
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