The introduction sets out the book’s main arguments and interventions, methodology, and structure. It details how the book applies the concept of ‘active reading’ to classical translation while challenging the idea that translators had a unified political agenda that reflected that of their patrons. It also outlines how the book reinforces the centrality of the concept of counsel and the agency of translators in producing diverse interpretations and applications of ancient Greek and Roman texts. It draws on the concept of the public sphere to conceptualize the shared political import of classical translations. The book’s innovative methodology combines literary-textual, book historical, and historical-contextual approaches and expands the canon to bring out the full range of applications and interventions of early modern translations of the classics while connecting them to larger developments. It ends by explaining the organization of the book according to the main genres of ancient Greek and Roman prose in translation between 1530 and 1580: moral philosophy, history and biography, military manuals, and oratory.