In recent years, an increasing number of teachers in Japan have taken leaves of absence due to mental health problems, largely attributed to the substantial stress of managing students’ psychological and behavioral difficulties, as well as increasingly adverse working conditions. Research suggests that reduced levels of self-esteem and self-efficacy in the teaching profession are linked to this trend, with general self-esteem influencing both domain-specific self-esteem and self-efficacy. As developing these psychological resources can be particularly difficult under such adverse environments, it is crucial to foster self-esteem and self-efficacy in the teaching profession among university students who aspire to become teachers.

The present study aimed to examine the influence of general self-esteem, and self-esteem and self-efficacy in the teaching profession on the aspiration to become teachers among university students enrolled in a teacher training program.

Participants completed the survey twice, once in their first year and again in their second year of university, approximately one year apart. The final sample comprised 193 students (62.2 % female) enrolled in a national teacher-training university in a regional city, all of whom were preparing to become teachers.The measures included the Self-Esteem and Self-Efficacy Scales in the teaching profession, the Intrinsic Self-Esteem Scale for general self-esteem, and an item assessing aspiration to become a teacher. The survey was conducted online.

After confirming high internal consistency for all scales, the hypothesized causal relationships among the variables were examined using path analysis. Regarding self-efficacy in the teaching profession, general self-efficacy and the three subscales (classroom and teaching management, student guidance, and collaboration with others) were examined separately in the model. Because general self-efficacy and the subscales were highly correlated, they could not be entered simultaneously in the path model. The models demonstrated an acceptable fit, with all path coefficients being significantly positive. The results supported a sequential pathway in which general self-esteem predicted self-efficacy in the teaching profession, which in turn predicted self-esteem in the teaching profession, ultimately leading to aspiration to become a teacher.

The level of aspiration to become a teacher was influenced by self-esteem and self-efficacy in a sequential order: general self-esteem, self-efficacy in the teaching profession, and self-esteem in the teaching profession. These findings suggest that fostering self-esteem and self-efficacy related to the teaching profession is essential for university students in teacher training programs to realize their ambition to become teachers.

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With the rise of Artificial Intelligence (AI) in higher education, it has become essential to assess its impact on the academic performance of nursing students.

This study aims to compare the impact of traditional teaching and an AI-generated video-based method on the academic performance of students at the Higher Institute of Nursing Professions and Health Techniques of Oujda.

A quasi-experimental study was conducted among 68 polyvalent nursing students enrolled in the fourth semester of the Bachelor’s program. Each participant attended two successive teaching interventions within the module Psychiatric Disorders and Nursing Care: a traditional lecture and a session integrating an educational video produced by AI. For each session, a pre-test and post-test were administered to assess students’ learning outcomes. Paired-sample t-tests were used to compare the mean scores, with a 95% confidence interval (CI 95%) and a significance level set at p = 0.05.

Students showed a significant improvement in their results after both teaching methods. However, the traditional method led to a higher average gain of 10.27 points, compared to 2.60 points with the AI-based method, with a highly significant difference (p < 0.001).

Despite the pedagogical potential of AI, the findings indicate that traditional teaching remains more effective in improving academic performance. The lack of interaction and the uniformity of AI-generated content may explain these limitations. A hybrid integration combining human pedagogical guidance with AI tools appears to be a more suitable approach to optimize learning.

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In the context of the digital expansion and the growing influence of social media, influencers play a major role in shaping social norms and modifying the behaviors of their users.

This cross-sectional observational study aims to identify the behaviors encouraged by content creators among the Moroccan population, as well as the factors associated with trust levels and the perceived influence of consumption recommendations.

An online questionnaire was distributed. A total of 1,006 active social media users aged 18 years and older from various cities across Morocco were recruited. The data were analyzed to identify positive and negative behaviors encouraged by influencers, as well as the factors determining trust and perceived influence.

Data analysis shows that more than half of the respondents believe that influencers contribute to the dissemination of social norms. Regarding negative behaviors, 59.6% of participants reported the normalization of provocative clothing, 39.6% indicated psychological pressure related to social comparison, and 34.6% acknowledged the promotion of a culture of superficiality. Conversely, positive behaviors cited include the popularization of scientific content (47.3%), awareness-raising of appropriate behaviors (40.5%), and the promotion of a healthy lifestyle (37.2%). Factors significantly associated with trust in influencers and perceived influence include content quality and the themes addressed, regardless of the domain (fashion, beauty, sports, nutrition, education, travel, personal development).

This study highlights the tangible impact of influencers on behavioral and social practice changes among Moroccans. These findings underscore the importance of strengthening digital literacy and promoting the rational and responsible use of social media

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Newborn screening (NBS) is a cornerstone of early detection for severe congenital disorders. However, the increasing scope of NBS programs has led to a higher frequency of false-positive (FP) and inconclusive (IC) results, which may generate significant psychological distress among parents. In Morocco, particularly in eastern Morocco, where NBS implementation is still developing, understanding these psychosocial consequences is essential for improving parental support and program acceptance.

To assess the psychological and behavioral impact of false-positive and inconclusive NBS results on parents in eastern Morocco.

A cross-sectional descriptive study was conducted between March 2024 and June 2025 among 120 parents (40 FP, 30 IC, and 50 controls) recruited from public maternity hospitals across eastern Morocco. Standardized questionnaires wereused to measure anxiety (State-Trait Anxiety Inventory, STAI), parental stress (Parenting Stress Scale, PSS), and perceived child vulnerability. Semi-structured interviews complemented the quantitative data to capture parental emotional experiences and perceptions of communication with clinicians.

Meananxiety scores were significantly higher among FP (M = 54.2 ± 8.6) and IC parents (M = 50.8 ± 7.9) compared with controls (M = 38.5 ± 6.4; p < 0.001).

Approximately 68% of FP parents said that they felt an intense fear related to perceived disease severity, and 42% sought repeated medical consultations before receiving confirmatory results.

Perceived child vulnerability remained elevated three months after the confirmation in 37% of FP parents. Qualitative findings revealed limited pre-screening information and anxiety-inducing communication during result announcement.

These findings highlight that false-positive and inconclusive newborn screening results exert a significant psychological impact on parents in eastern Morocco. Strengthening communication strategies, enhancing healthcare provider training, and establishing a structured psychological support system are essential to reduce this distress and reinforce parental trust in the national newborn screening program.

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Childhood Apraxia of Speech (CAS) was declared as a motor speech disorder by ASHA (2007). Yet, until then it was mainly addressed as a phonological disorder and until these days, 18 years later, the treatment of CAS is yet to be motor based worldwide. Although the motor declared guidelines by ASHA and by other professionals in other countries, professionals finds it hard to diagnose it clearly due to comorbidity with communication and language disorders. Only very small percentile of children with speech disorder referred to yaelcenter in the last 25 years were diagnosed with CAS although they were all suspected for it.

This non clarity might lead to non-accurate treatment since the essence of the syndrome is not addressed. An accurate treatment will integrate knowledge from several domains: communication, Language, Sensory, behavioural, emotional, cognitive and, the most important one for CAS, motor learning.

Motor learning is an area of knowledge which is learnt usually in sport academy, while Its main practical purpose is to improve training methods in sport. The use of motor learning knowledge doesn’t belong to the world of sport primarily but rather to the world of movement wherever it exists. One of the fascinating areas of movement is speech.

Speech in its basic form is motor based, before it being used as a motor tool for language and communication. It is the most complicated motor task in the human body since for every syllable we activate directly and indirectly over 100 muscles. The timing of all the muscles in producing just one syllable is about 100-200 milliseconds. Full speech utterances which include many sentences, require high motor control due to the high complexity of the motor system. Surprisingly, children acquire speech spontaneously, without direct guiding. It happens because the peripheral and central nervous systems enable that. The children who can’t acquire speech spontaneously due to severe deficit in motor planning, need to practice motor speech tasks repeatedly and accurately.

The VML method (Verbal Motor Learning) is designed to solve this problem. It uses unique speech motor analysis, manual techniques and motor learning principles in order to directly teach the basic milestones of speech for children with CAS. The system is using 20 motor learning principles in depth, being considered in every motor speech task, while bringing high quality and accuracy to treatment. The treatment knowledge is researched based even if not specific to speech.

The presentation will discuss the use of MLP in the service of Apraxia of speech mainly among children diagnosed with Autism where the phenomenon is frequently found.

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Parkinson’s Disease (PD) is a chronic neurodegenerative pathology, characterized by nigrostriatal dopaminergic dysfunction and motor manifestations. Dopamine agonists (DA) are one of the pillars of treatment. However, the stimulation of dopamine receptors in the mesolimbic pathways has been associated with the appearance of neuropsychiatric adverse effects, namely impulse control disorders (ICD), including pathological gambling, hypersexuality, impulsive shopping and binge-eating. These clinical manifestations have a significant clinical impact, jeopardizing patients’ functionality and quality of life.

Review the literature regarding the scientific evidence on the association between the use of DA and the development of ICD in patients with PD.

Non-systematic review based on a search for scientific articles, between 2010 and 2024, in Pubmed using the MeSH terms: ‘dopaminergic agonists’, ‘impulse control disorder’, ‘Parkinson’s disease’.

The analysis published in 2022, based on data collected between 1968 and 2020, showed a high incidence of ICD in patients medicated with dopamine agonists. Pramipexole and ropinirole showed a clear association with pathological gambling, hypersexuality and impulsive buying behavior.

A prospective study by Weintraub found that 17.1 percent of patients exposed to DA developed at least one form of ICD. It should be noted that behavioral symptoms showed a dose-dependent relationship, and in many cases regressed after the agonist was reduced or discontinued. The risk of ICD associated with ropinirole increases proportionally with the plasma concentration of the drug, while with pramipexole, the risk remains high even at lower serum levels, suggesting an intrinsic affinity of this compound for D3 receptors in the limbic regions.

On a neurobiological level, in patients with ICD, a significant reduction in the availability of D3 receptors in the ventral striatum and an increase in the release of dopamine in this region in response to reward stimuli, such as risky behavior, were observed. This supports the hypothesis of limbic dopaminergic sensitization induced by chronic exposure to DA.

Several predisposing factors have been identified as potentiating the risk of developing ICD, such as early onset of PD, personal and family history of addictive behaviors, impulsive personality traits, and pre-existing psychiatric comorbidity.

Scientific evidence shows a clear association between the use of dopamine agonists, particularly pramipexole and ropinirole, and the development of ICD in Parkinson’s patients. This relationship is mediated by neurobiological mechanisms involving D3 dopamine receptors and reward circuits. The presence of individual risk factors reinforces the importance of regular monitoring of risk behaviors, optimizing therapy and educating patients and carers in order to prevent and intervene effectively in these situations.

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Bruxism is a masticatory muscle activity characterized by clenching and/or grinding of the teeth without a functional purpose, which can occur during sleep and while awake. The prevalence of awake bruxism is thought to be 22.1% to 31%, while sleep bruxism is thought to be 12.8%. Bruxism can lead to problems such as fractures and abrasions in teeth, loss of support and mobility in periodontal tissues, pain in the chewing system and orofacial region, and temporomandibular joint dysfunction. It is known that bruxism is associated with mental disorders, anxiety and intensity of stress. Bruxism has been reported to be significantly more common in children with attention deficit hyperactivity disorder (ADHD). There is an association between bruxism and ADHD, but studies on ADHHD and bruxism in adults are uncommon.

The aim of the study was to evaluate whether generalized orofacial pain complaints such as teeth grinding, jaw pain, jaw clicking, and headache were more common in those diagnosed with ADHD and/or taking psychostimulant medications.

This study was conducted in the psychiatry clinic of a city education and research hospital between October 2024 and January 2025. A cross-sectional study was conducted on adults over the age of 18 diagnosed with ADHD who applied to the psychiatry outpatient clinic. Forty three participants met the eligibility criteria were included in this study. ADHD diagnose was based on the criteria of DSM-5. Self-report and clinical examination were used for bruxism. The presence and severity of temporomandibular joints disorder in the participants were evaluated using the Fonseca Anamnestic Index (FAI). The presence of bruxism in the participants was examined using a standardized assessment form (Standardized Tool for the Assessment of Bruxism-STAB Axis A).

The sample had a mean age of 32.7 years, of which 68% were male and 32% were female. Sleep bruxism and awake bruxism were evident in 51.2% and 58.1% respectively.

Since bruxism is statistically significantly associated with ADHD, further studies on this subject would be useful. Awareness of ADHD symptoms in cases of bruxism will increase compliance with treatment and thus reduce orthodontic complications. Therefore, increasing awareness of the relationship between bruxism and ADHD will provide a multidisciplinary approach to treatment.

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In recent years in Japan, issues concerning children’s health and adjustment have been reported, and teachers’ working conditions have also deteriorated. As a result, sick leave and burnout among teachers have increased. Moreover, fewer university students are choosing teaching as their future career. Yamasaki and Uchida (2025) suggested that a preventive approach is necessary for university students in teacher training programs.

This study aimed to longitudinally examine the influence of various activities in a teacher training university on self-esteem and self-efficacy in the teaching profession and on career aspirations to become teachers.

Participants were 193 university students (M = 18.43 years, SD = 0.54) who aimed to become teachers. They completed a battery of six questionnaires at two time points: once at university entry (Time 1) and again in their second year (Time 2). The questionnaires included the Scale of Self-Esteem in the Teaching Profession (Yamasaki & Uchida, 2023); the Scale of Self-Efficacy in the Teaching Profession (Yamasaki & Uchida, 2024), which assesses classroom and instructional management, student guidance, collaboration with colleagues, and overall self-efficacy; the General Self-Efficacy Scale (Yamasaki et al., submitted manuscript); the Teaching Career Aspiration Scale; and the Reasons for Changes in Teaching Career Aspiration Scale, which assessed whether teaching career aspiration had increased or decreased and the reasons for these changes. The reasons were assessed at Time 2, reflecting the past year.

We calculated the changes in each variable from Time 1 to Time 2. Pearson correlation coefficients were then computed to examine the relationships between these changes and the reported reasons for increases or decreases in teaching career aspiration. The results indicated that “having conducted satisfactory lessons at the university” was positively correlated with self-esteem and self-efficacy (student guidance) in the teaching profession as a reason for an increase. In contrast, “loss of interest in teaching due to coursework related to teacher education” was positively correlated with self-esteem in the teaching profession as a reason for a decrease.

This study suggests that self-esteem and self-efficacy in the teaching profession are associated with the reasons for both increases and decreases in teaching career aspiration. Especially, the findings indicate that university coursework may help prevent a decline in teaching career aspiration. These results can be considered by university staff to maintain or enhance students’ teaching career aspiration.

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Perimenopause is characterized by dynamic fluctuations in ovarian hormones, particularly estrogen and progesterone, which exert modulatory effects on neurotransmitter systems implicated in cognition, mood regulation, and executive functioning.

In women with neurodevelopmental disorders such as attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), these hormonal transitions may interact with pre-existing neurobiological vulnerabilities, contributing to symptom exacerbation and functional decline.

Despite increasing recognition of sex- and gender-specific presentations of ADHD and ASD, the impact of perimenopausal neuroendocrine changes remains largely underexplored. Preliminary evidence suggests that estrogen withdrawal may intensify deficits in dopaminergic and serotonergic signaling, potentially worsening attentional control, emotional regulation, and social cognition. Clinical reports further indicate heightened psychiatric comorbidity, treatment resistance, and decreased quality of life during this life stage.

This workshop will provide an overview of current evidence on the intersection of perimenopause and neurodevelopmental disorders, including neurobiological mechanisms, clinical phenomenology, and methodological limitations in existing research. We will discuss implications for future studies, but also the role of psychopharmacology, hormone replacement therapy, and multimodal interventions.

By integrating neuroscientific insights with clinical observations, this workshop aims to delineate a research agenda and stimulate interdisciplinary dialogue on a neglected yet critical dimension of women’s mental health.

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Regular prayer in religious traditions such as Islam and Christianity is not only a spiritual practice but also has measurable neurobiological effects on the brain and body.

Neuroimaging and physiological studies show that prayer—especially with focused attention and breath control—activates brain regions associated with calm, emotional regulation, and relaxation, including the prefrontal cortex, limbic system, and autonomic nervous system.

The relationship between prayer, fasting, and psychiatry is multidimensional, involving both psychological and neurobiological mechanisms that can have significant impacts on mental health. Religious practices such as regular prayer and ritual fasting (e.g., Ramadan in Islam or fasting periods in Christianity) are increasingly recognized for their benefits in emotional regulation, stress management, and even cognitive performance

Neurobiology of prayer and fasting on mental health The neurobiology of prayer and fasting on mental health is a fascinatingarea of study that explores the physiological and psychological effects of these spiritual practices.

The review of litterature and different researchs

Prayer, particulary regular prayer practiced in religious traditions like islam, Christianity, a,d others, is often perceived as a means of spiritual connection, but it also hasmeasurable effects on the brain.

Activation of brain regions associated with relaxation :Prayer canactivate brain regions related to relaxation and calm, such as the prefrontal cortex and the limbic system (wich regulates emotions) These area are involved in stress management, emotional regulationand activation of feelings of inner peace Reduction in activation on the stress system:Meditativepractices like prayer can modulate the hypothalamic -pituitary-adrenal (HPA) axis, wich is responsible for the stress response.

Reducing stress, decreasing inflammation, and promoting neurogenesis, these ritualscan contribute to better emotional balance and mental well being These findings open the door to more integrated approaches, recognizing religious and spiritual practices as potentially protective factors for mental health.

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Brugada syndrome is an inherited cardiac channelopathy associated with an increased risk of sudden cardiac death. Certain psychotropic medications, particularly antipsychotics, have been implicated in unmasking Brugada-type electrocardiographic (ECG) patterns. Recognizing such drug-induced cardiac events in patients with severe psychiatric disorders is critical to prevent fatal outcomes.

To report a case of Brugada-type ECG changes in a patient with resistant schizophrenia under antipsychotic polytherapy, and to discuss the clinical implications for psychiatric management.

We describe the clinical course of a male patient with resistant schizophrenia, hospitalized in the Department of Psychiatry for suicidal behavior. His treatment regimen included amisulpride, aripiprazole, and chlorpromazine. Routine investigations were conducted, including ECG, laboratory analyses, and EEG. A cardiology consultation was obtained.

During hospitalization, ECG demonstrated transient coved-type ST-segment elevation in the right precordial leads, consistent with a Brugada-type pattern. Laboratory tests and EEG were unremarkable. Cardiology evaluation confirmed suspicion of Brugada syndrome. Consequently, clozapine initiation was withheld, chlorpromazine was discontinued, and the patient was maintained on amisulpride combined with aripiprazole. He was subsequently referred to a specialized rhythmology unit. ECG abnormalities resolved following the withdrawal of chlorpromazine.

This case highlights the potential of antipsychotic agents, particularly phenothiazines such as chlorpromazine, to induce Brugada-type ECG changes. The mechanisms may involve sodium channel blockade, which is particularly concerning in patients at risk for arrhythmogenic events. Clinicians should be vigilant in monitoring cardiac function when prescribing antipsychotics, especially in polytherapy, and collaborate with cardiology to optimize patient safety.

Brugada-type ECG changes can occur in patients treated with antipsychotics, posing a risk of severe arrhythmia and sudden cardiac death. Careful cardiac monitoring, timely recognition of ECG abnormalities, and interdisciplinary management are essential in such cases.

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Work-related musculoskeletal disorders (WMSDs) represent a major occupational health problem in healthcare professions, affecting productivity, quality of care, and well-being. Healthcare workers are exposed to physical and psychosocial risk factors, including repetitive movements, awkward postures, and high cognitive and emotional demands. The NASA Task Load Index (NASA-TLX) is a validated multidimensional tool that quantifies subjective workload across six domains (mental, physical, temporal demands, performance, effort, and frustration). Understanding the relationship between perceived workload and WMSDs may guide preventive interventions in healthcare settings.

This study aimed to evaluate the association between the occurrence of WMSDs and the level of subjective workload measured by NASA-TLX among healthcare personnel, including nurses, nurse assistants, anesthesia technicians and geriatric caregivers.

A cross-sectional analytical study was conducted among healthcare workers in hospital departments. Participants completed a self-administered questionnaire including sociodemographic data, occupational characteristics, the Nordic Musculoskeletal Questionnaire for WMSDs screening, and the NASA-TLX scale for workload assessment. Statistical analyses were performed using SPSS software. Descriptive statistics summarized prevalence and workload scores, while chi-square tests and logistic regression identified associations between WMSDs and workload dimensions.

Among the participants (n = 146), 28.8 % were males with a mean age of 34.44 ±6,9 years. the overall prevalence of WMSDs during the past 12 months was 75%, with the lumbar (66.4%), cervical (61%), and shoulder (50%) regions being the most affected. Concerning the workload, the highest subscale of NASA-TLX score observed for physical (79±17 /100) and temporal (76,2 ± 25 /100) demands. However, no statistically significant association was found between global or individual NASA-TLX dimensions and the presence of WMSDs (p > 0.05).

Although WMSDs were common among healthcare personnel, this study did not reveal a significant link between subjective workload assessed by NASA-TLX and musculoskeletal complaints. These findings suggest that factors other than perceived workload—such as ergonomic constraints, repetitive movements, and postural strain—may play a more dominant role in WMSD development. Future longitudinal studies are needed to better understand the complex interaction between workload perception and musculoskeletal health in healthcare environments.

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Various cognitive and environmental factors influence an individual’s creative abilities. However, the link between creative potential and certain affective traits remains largely unexplored, particularlyamong artistic populations.

The objective of this study is to investigate the links between different affective temperaments and creative skills in a population of students from the Institute of Arts and Crafts of Sfax.

Our study was cross-sectional, descriptive and analytical, conducted between February 1st to March 5th, 2025, among students at the Institute of Arts and Crafts in Sfax. Data were collected using a form that included sociodemographic and clinical characteristics, as well as two psychometric scales in their Arabic versions: Epstein Creativity Competencies Inventory for Individuals (ECCI-i) to assess creative skills and Tunisian TEMPERAMENT Scale (TEMPS) to measure affective temperaments.

A total of 60 students participated in the study, divided into 23 men and 37 women, with a sex ratio of 0.6. The median age was 20 years [19-22 years].

Regarding creative skills, 3.3% of students displayed weak creative skills, 23.3% average creative skills, and 73.3% high creative skills.

Furthermore, 76.7% of students reported that their creativity or artistic work strongly influenced their emotions. Additionally, 61.7% of participants reported feeling more creative during periods of sadness or euphoria.

Our study revealed that students with high creative skills had significantly higher scores on cyclothymic and hyperthymic temperament compared to those with average or low creative skills (p = 0.001). However, depressive, irritable, and anxious temperaments did not show a significant association with creative skills.

These results support a strong link between creative skills and affective profiles characterized by instability, reactivity, and dynamism. A better understanding of these interactions could lead to improved support for these students in managing their emotions and optimizing their creative potential.

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While the focus of research and diagnostics has shifted from non-verbal, low-IQ Autism to high-functioning Autism it has become more apparent that there is a discrepany between the number of males and females being diagnosed. These findings are not only presented in epidemological studies but in studies which attempt to actively identify cases in the general population as well. This leads to the question whether there is an inherent difference in the prevalence or if we are not as good as detecting Autism in females and if so, why that might be. This talk will give an overview of the research already conducted in this area as well as concerete examples from years of Autism diagnostics.

• - This talk was already accepted for the EPA 2025, however, due to a freshly broken leg unfortunatly I had to excuse myself and be absent from the congress. Therefore I would like to submit this topic again. If this is not possible due to my absence last year or because the topic is not of interest two years in a row, I fully understand. -

The aim of this presentation is to increase awareness of the presentation of symptoms of Autism in women and the real life implications in the diagnostic process.

This presentation will conclude from the statistical research drawn from various sources, such as Global Burden of Disease study published in the Lancet and the recent numbers by the CDC for a broad epidemiological background and shift to the real life implications in the day to day life in a diagnostic centre for Autism.

According to the Global Burden of Disease Study 2021 the prevelance of Autism in females is 0.5% to the male 1.1%. However, in experienced clinical settings, the number often shifts even further toward the male population. Since female presentation tends to be overlooked, this talk aims to focus on the differences in the gender presentation.

Through this talk hopefully the perspective of judging symptoms according to their gender presenation should become clearer.

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Acute Generalized Exanthematous Pustulosis (AGEP) is an uncommon drug eruption reaction following intake of medications such as antibiotic, antihypertensive, and antiepileptic drugs. When untreated, this can lead to severe organ dysfunction. With the use of psychotropic and antiepileptic medications in the treatment of bipolar disorder, existing published literature about AGEP in patients with bipolar disorder treated with psychotropics and antiepileptic medications remains relatively rare. Managing AGEP involves supportive care, corticosteroid and antihistamine therapy.

To describe a case of acute generalized exanthematous pustulosis in a patient with bipolar disorder, highlighting the clinical presentation, diagnostic process in resource-limited setting, and management.

This case report aims to describe the course of treatment of a Filipino woman diagnosed with bipolar disorder with psychosis who developed acute generalized exanthematous pustulosis while being treated with Risperidone and Valproic acid.

A 57-year-old female was admitted at the Psychiatric unit as a case of Bipolar I disorder, current episode manic with psychotic features. She was managed with Olanzapine 10mg/tab per day and Valproic Acid 1000mg/tab per day. She was initially noncompliant with Valproic acid and preferred Olanzapine monotherapy. After a few days, the Olanzapine dose was increased to 20 mg per day due to persistent psychosis. However, since there was no improvement in psychosis by hospital day 9, the medication was switched to Risperidone 2mg per day. On hospital day 10, with regular intake of Risperidone and Valproic acid, she developed erythematous papular lesions on the anterior and posterior trunk, which progressed to generalized erythematous pustular lesions involving the neck, trunk, upper extremities, thighs, and the groin, sparing the oral mucosa, palms, soles, and feet. Febrile episodes (37.9 to 39.1C) were noted. Complete blood count revealed neutrophilia (18,500/mm3) and a decrease in platelet count (132,000/mm3). Both medications were immediately discontinued. Referral to Dermatology was done and was diagnosed clinically, with Acute Generalized Exanthematous Pustulosis secondary to use of Risperidone and Valproic acid (EuroSCAR 9). She was started on intravenous and topical corticosteroids, leading to improvement of her lesions after eight days of continuous treatment.

Vigilant monitoring is necessary whenever a patient starts with psychotropic medications because side effects like AGEP may occur within the first week of treatment. Early initiation of intravenous and cutaneous treatment can provide rapid relief of symptoms.

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Individuals with severe mental illness (SMI) have a life expectancy 10-to-20-years shorter than the general population. Increased morbidity and mortality is frequently due to preventable physical health conditions. In diabetes, those with an SMI have significantly worse health outcomes. These outcomes are particularly apparent in inpatient groups, where it is estimated that 10% have Type 2 Diabetes (T2DM) and 1% have Type 1 Diabetes (T1DM). Managing diabetes in psychiatric inpatients is challenging, and integration of diabetic care into psychiatric care remains inconsistent. Inpatient admission is a missed opportunity for improving the diabetic care of those with SMI.

The goal of this survey was to understand current practices, confidence levels, and perceived barriers when managing diabetes across the multidisciplinary team at the Royal Edinburgh Hospital (REH), a large psychiatric hospital in Scotland. These insights can be used to improve staff education, guidance and patient care.

A 13-item questionnaire was used to evaluate healthcare professionals’ understanding, and confidence in managing diabetes in an inpatient psychiatric setting. Participants were also asked to evaluate their perception of the quality of care provided to inpatients. Participants included all staff authorised to prescribe or dispense insulin. The questionnaire was sent via an anonymous electronic survey to all hospital subspecialities.

69 responses were collected from six subspecialties across the REH: 42 nurses, 24 doctors, and 3 allied healthcare workers. Participants agreed they were confident in monitoring blood glucose (81% - 56/69), treating low blood sugar (88% - 61/69), treating high blood sugar (80% - 55/69), understanding the difference between T1DM and T2DM (83% - 57/69), and understanding the difference between long and short acting insulin (68% - 47/69). However, only 33% (23/69) agreed that the quality of diabetic care that patients received on the ward was of an acceptable standard. Respondents noted limited access to specialist services and resources. Only 14% (10/69) had received any training in the management of diabetes in the past 12 months. Lack of training was highlighted in comments. For example, one respondent wrote “for a type 1 diabetic, I feel there is little to no training”.

Staff generally agreed that they were confident in managing diabetes. However, concerns were raised about lack of staff training and expert support. There was a widespread perception that inpatient diabetic care was of an unacceptable standard. Our study recommends improving staff education, developing psychiatric setting–specific diabetes protocols, and establishing links with diabetes specialist teams.

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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that starts from childhood and lasts through adulthood. Despite its high prevalence and impact, adults ADHD remains undiagnosed and untreated, not only but mainly in women.

The short version of the Adult ADHD Self-Report Scale (ASRS) composed of 6 items has been shown to outperform the original 18-item scale. The updated version for DSM-5 criteria (ASRS-5) has high psychometric and operating characteristics, being recommended for adult cases detection in the general population.

To analyse the psychometric properties (construct validity and internal consistency) of the Portuguese version of the ASRS-5.

792 adults from the general population (71.5% females; 28.5% males), with a mean age of 30.91 (±15.05; range:18-74) years, completed an online survey including the ASRS-5.

The Confirmatory Factor Analysis of the unidimensional model resulted in “good” / “very good” fit indices (χ2/gL=2.772; CFI=.9888; TLI=.9790; GFI=.9115; RMSEA=.0467; p<0.001). Factor loadings ranged from 0.565 to 0.741.

Internal consistency resulted in Raykovs Omega 0.861 and Cronbach’s α=0.799.

Total scores were significantly higher in women (7.443±4.426) than in men (6.491±4.334; T Student=-2.750, p=0.006).

ASRS-5 Portuguese version present adequate construct validity and reliability, with results comparable to those found in the original English and other versions. Our results are also in line with growing evidence that this condition may affect women more than men. This psychometric study represents a first contribution to both clinical and research on ADHD in Portugal. In a near future study, we intend to analyse its sensitivity and specificity, to identify the cut-off point with the best accuracy for the Portuguese population. Since the group of Portuguese speakers is larger and more culturally diverse than the Portuguese population, it will also be important to explore the ASRS-5 validity, reliability and screening accuracy with samples from other Portuguese-speaking countries.

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The research was conducted on a sample of 12 patients in the postpartum period, of whom 8 had postpartum depression, and 4 had postpartum psychosis. The influence of aripiprazole on prolactin level and therapeutic outcome was analyzed. In patients with postpartum depression, those who received aripiprazole had a more pronounced decrease in prolactin and a shorter hospitalization. Similar findings were recorded in patients with psychosis. The findings indicate a potential benefit of aripiprazole in the treatment of postpartum disorders.

The connection between hormonal changes and psychological disorders in the postpartum period is complex and is the subject of numerous studies. Prolactin, a hormone that increases after childbirth, can be associated with the development of depressive and psychotic symptoms. The aim of this study was to examine the association of prolactin level with the intensity of symptoms and the effect of aripiprazole.

The sample included 12 patients hospitalized for postpartum psychological disorders. Eight patients were diagnosed with postpartum depression, and four with postpartum psychosis. In patients with postpartum depression, two groups were formed: group A (n=4) received an antidepressant and aripiprazole (5 mg), while group B (n=4) received only antidepressants. For postpartum psychosis, two patients received aripiprazole in addition to olanzapine, and two only olanzapine. Initial and control measurement of prolactin level was performed in both groups.

In patients with postpartum depression, the maximum prolactin level was 785 mIU/L. In Group A there was a 38% drop in prolactin, while in Group B the drop was 17%. The average duration of hospitalization was 18 days for Group A and 26 days for Group B.

In patients with postpartum psychosis, the maximum prolactin level was 1478 mIU/L. A greater therapeutic response and decrease in prolactin was observed in patients who received aripiprazole compared to those who received olanzapine.

During hospitalization, a control measurement of prolactin was carried out, which confirmed a more pronounced drop in the groups that received aripiprazole.

The control measurement of prolactin showed a more pronounced reduction in the group of patients receiving aripiprazole. At the same time, a shorter stay in the hospital and a better therapeutic response were recorded. These findings support the hypothesis that aripiprazole, as a partial agonist of the D2 receptor, can have a beneficial effect in the regulation of postpartum mental disorders along with hormonal stabilization.

Aripiprazole in low doses can have a beneficial therapeutic effect not only on symptoms but also on prolactin regulation. Research limitations are:

• - A small sample of respondents

• - No randomization

None Declared

Studies and the S3 practice guidelines in psychiatry and psychotherapy show that health-promoting measures are highly relevant in the treatment of mental illness. Current psychiatric care research still shows ambivalent findings regarding the effects of specific diets on psychopathogenic symptoms. In particular, the quality of nutrition and different effects in a psychosomatic context are the focus of studies on different eating habits. Research results outside of biomedical markers are subject to limitations with regard to a psychotherapeutic perspective on nutrition and its influence on mental health. The influence of mindfulness-based interventions in the context of third-wave psychotherapy on the improvement of psychopathogenic symptoms has been comprehensively documented. Mindfulness-related aspects also appear to be significant in the context of nutrition. This intervention study addresses this research gap by examining the influence of mindfulness-centred nutritional therapy on the improvement of mindful eating behaviour, the effects of psychopathogenic symptom severity and structure-promoting nutritional skills, thus taking an alternative, scientific perspective on nutrition and mental health.

What influence does mindfulness-based nutritional therapy have on improving psychopathogenic symptoms?

Following a newly developed, mindfulness-focused nutritional therapy consisting of theoretical and practical units, patients in the intervention group at a specialist psychiatric-psychosomatic hospital completed a four-week therapy unit consisting of several modules. In a measurement taken at three different points in time, a battery of questionnaires was used to examine the influences and modifications of mindfulness and to survey mindfulness-based factors in the context of nutrition, as well as changes in eating patterns towards health-promoting eating behaviour and possible effects on overall psychological stress.

The descriptive and inferential statistical results of the study are presented using regression analyses and multifactorial ANOVA with repeated measurements.

In accordance with the existing research gap, initial conclusions are to be drawn about the possible influence of a mindfulness-based nutritional intervention on improving mindfulness-based nutritional skills and reducing overall symptom severity. Based on the exploration of the possible influence of a multimodal therapy unit, the aim of the study is to investigate the causal effectiveness factors of the application-focused, mindfulness-based nutritional intervention using further influencing variables in a control group setting along nutritional problems of patients with psychopathogenic symptoms, as well as to derive possible implications for the treatment of mental illnesses.

None Declared

Research on psychedelic compounds has grown quickly in the past decade. Yet molecule-specific, quantitative summaries are scattered, making it hard to see how interest differs by compound or over time.

To quantify PubMed-indexed publications on ketamine, lysergic acid diethylamide (LSD), N,N-dimethyltryptamine (DMT), psilocybin, and psilocin; to describe annual trends over the last decade; and to identify the most frequently studied compound. Where available, we note planned stratification by publication type (Systematic Review, Scoping Review, Review, Meta-Analysis, Case Report, Classical Article).

On 28 October 2025 we searched PubMed (MEDLINE) using compound-specific terms and synonyms. Annual counts were extracted from PubMed Timeline and compiled into year-by-year tables. We summarized totals, the share published in 2021–2025, peak annual outputs, and compound annual growth rates (CAGR) for 2015–2025. Publication-type stratification will use the PubMed “Publication Type” field; detailed breakdowns will be presented in figures without inferential analyses.

We identified 9,334 records across five compounds: ketamine 5,704 (61.1%), LSD 1,497 (16.0%), DMT 1,047 (11.2%), psilocybin 999 (10.7%), and psilocin 87 (0.9%). Ketamine led in total and annual volume, with the highest single-year counts (480 in 2024; 475 in 2025). Psilocybin showed the fastest growth, increasing from 12 publications in 2015 to 194 in 2025 (CAGR ≈32.1%) and setting consecutive highs in 2023 (n=148), 2024 (n=187), and 2025 (n=194). DMT rose from 30 (2015) to 112 (2025; CAGR ≈14.1%), peaking in 2024 (n=122). LSD increased from 38 (2015) to 117 (2025; CAGR ≈11.9%) with a 2024 peak (n=122). Psilocin remained small but accelerated from 3 (2015) to 18 (2025; CAGR ≈19.6%), peaking in 2025 (n=18). Concentration in 2021–2025 varied by compound: psilocybin 74.0% (739/999), psilocin 63.2% (55/87), DMT 52.3% (548/1,047), ketamine 38.9% (2,221/5,704), and LSD 34.9% (523/1,497). LSD shows sustained activity since the late 1960s; ketamine has grown steadily over five decades; psilocybin and DMT surged in the 2020s. The most studied compound was ketamine (5,704/9,334; 61.1%). Among serotonergic psychedelics, psilocybin achieved the largest contemporary annual total (n=194 in 2025).

The PubMed-indexed literature on psychedelics is large and still expanding. Ketamine dominates overall output and yearly peaks, while psilocybin is growing fastest, with a new high in 2025. DMT and LSD form substantial secondary literatures—reflecting strong activity since 2020 and long-running interest, respectively—whereas psilocin remains smaller but is accelerating. These quantitative markers, together with forthcoming publication-type profiles, point to a maturing field and a useful baseline for ongoing bibliometric tracking and targeted synthesis.

M. Pastuszak Grant / Research support from: Beckley Psytech, Compass Pathways, GH Research, MSD, K. Jakuszkowiak-Wojten Grant / Research support from: Alkermes, Allergan, Auspex Pharmaceuticals, Biogen, Cephalon, GH Research, GWPharmaceuticals, Janssen, KCR, Lilly, Lundbeck, Minerva, Orion, Otsuka, and Servier. Maria Gałuszko‐Węgielnik has received research support from: Alkermes, Biogen, Celon, Janssen, GH Research, KCR, Minerva Neurosciences, Lilly, and Servier, Novartis,Compass Pathways, M. Gałuszko-Węgielnik Grant / Research support from: Alkermes, Biogen, Celon, Janssen, GH Research, KCR, Minerva Neurosciences, Lilly, and Servier, Novartis,Compass Pathways, A. Kwaśny Grant / Research support from: Beckley Psytech, Compass Pathways, GH Research, MSD, A. Mechlińska: None Declared, D. Świeczkowski: None Declared, W. Cubała Grant / Research support from: Grants: Acadia, Alkermes, Allergan, Angelini, Auspex Pharmaceuticals, Beckley Psytech, BMS, Celon, Cephalon, Compass Pathways, Cortexyme, Ferrier, Forest Laboratories, GedeonRichter, GH Research, GWPharmaceuticals, HMNC Brain Health, IntraCellular Therapies, Janssen, KCR, Lilly, Lundbeck, MindMed, Minerva, MSD, NIH, Neumora, Novartis, Orion, Otsuka, Recognify Life Sciences, Sanofi, Seaport, Servier Honoraria: Adamed, Angelini, AstraZeneca, BMS, Celon, GH Research, GSK, Janssen, KRKA, Lekam, Lundbeck, Minerva, NeuroCog, Novartis, Orion, Pfizer, Polfa Tarchomin, Sanofi, Servier, Zentiva Advisory boards: Angelini, Celon (ended 2021), Douglas Pharmaceuticals, GH Research, Janssen, MSD, Novartis, Polpharma, Sanofi, Tasman Therapeutics