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Intimate partner violence (IPV) is a major global health and human rights issue. However, the association between IPV and specific mental disorders across different life stages, including pregnancy and postpartum, remains insufficiently quantified.
Aims
This systematic review and meta-analysis aimed to assess the associations between IPV and mental disorders among women in the general population, pregnant women and postpartum women.
Method
We searched six databases to identify cross-sectional, case–control and cohort studies published between 1 January 1980 and 13 June 2024. A random-effects meta-analysis model was performed to derive the pooled odds ratios and 95% confidence intervals.
Results
Of 7326 records identified, 82 studies with a total of 140 286 participants were included. For women in the general population, lifetime IPV was significantly associated with depression (odds ratio 2.26, 95% CI 1.83–2.79, p < 0.0001; class 1; moderate). Past-year IPV also demonstrated significant associations with depression (odds ratio 2.36, 95% CI 1.61–3.45, p < 0.0001; class 3; very low) and anxiety (odds ratio 2.85, 95% CI 1.61–5.05, p = 0.0003; class 3; low) among women in the general population. IPV during pregnancy was notably associated with depression (odds ratio 3.59, 95% CI 2.48–5.20, p < 0.0001; class 2; very low) and anxiety (odds ratio 3.27, 95% CI 2.60–4.10, p < 0.0001; class 1; moderate) in pregnant women. For postpartum women, lifetime IPV exposure was significantly linked to depression (odds ratio 2.09, 95% CI 1.54–2.83, p < 0.0001; class 3; moderate).
Conclusions
IPV is associated with depression, anxiety and eating disorders among women in the general population, pregnant women and postpartum women. Tackling the root causes of IPV and improving access to mental health services are critical steps in mitigating the long-term psychological burden on women worldwide.
This article gives an overview of the most common neuropsychiatric sequelae of traumatic brain injury (TBI), and discusses new perspectives on terminology for describing persisting symptoms after concussion. Psychiatrists may encounter patients who have sustained TBIs in a variety of settings, including in the out-patient clinic, in-patient services and when preparing expert psychiatric reports, especially in personal injury cases. TBI is a medical condition diagnosed by a brain injury expert such as a neurologist, neuropsychologist, neuropsychiatrist or neurosurgeon. Neuropsychiatric sequelae may occur following TBI and affect prognosis and treatment needs. This article explores the causes of TBI, its clinical presentation and guidelines for grading severity and considers the neuropsychiatric sequelae that can occur, including persisting symptoms after concussion.
Mental and physical disorders are leading contributors to global disability. However, estimates of their health-related burden often overlook the pervasive comorbidity among conditions. This study aimed to quantify the independent and combined effects of these disorders on self-rated health in nationally representative Chinese adults, explicitly accounting for comorbidity.
Methods
Data were drawn from the China Mental Health Survey (CMHS), a cross-sectional nationally representative survey. Mental disorders were assessed using the Composite International Diagnostic Interview 3.0, and physical disorders were measured through structured self-report. Health-related burden was assessed using a 0–100 visual analogue scale (VAS) of self-rated health over the past 30 days. Nested regression models examined disorder-specific and multimorbidity effects, followed by interaction-based counterfactual simulations to estimate disorder-specific burden net of comorbidity at individual and population levels.
Results
Among 27,505 respondents included in multivariate analyses, comorbidity was highly prevalent. In crude models, all 20 disorders were associated with lower VAS scores, with the largest decrements observed for mental disorders such as generalized anxiety disorder (GAD), bipolar disorder and major depressive disorder (MDD). After accounting for disorder type and comorbidity structure, many associations were attenuated and the independent effect of disorder count became non-significant. Counterfactual simulations showed the largest individual-level burdens for GAD (–14.71), cancer (–9.02), bipolar disorder (–8.59) and MDD (–8.53). At the population level, insomnia symptoms (–1.56), arthritis (–0.81) and cardiovascular disorders (–0.64) contributed the greatest burden.
Conclusions
Accounting for comorbidity substantially alters estimates of disorder-specific health burden. Mental disorders impose the greatest impairment at the individual level, whereas prevalent physical conditions dominate population burden.
To examine the associations between various hurricane-related exposures and psychiatric and substance use disorders among Puerto Rican adults following Hurricane Maria and to identify disaster-related exposures that may contribute to psychiatric morbidity in hurricane- and typhoon-prone settings.
Materials and Methods
Hurricane-related exposures were grouped into personal, property, utility/resource losses, and unsanitary/hazardous exposures. Logistic regression models were run to examine the associations between the number of hurricane-related exposures and disorders.
Results
Each additional hurricane-related exposure was associated with a 1.1 percentage-point increase in the probability of any mood disorder (P < 0.001), a 1.3 percentage-point increase in the probability of any anxiety disorder (P < 0.001), and a 2.0 percentage-point increase in the probability of any disorder (P < 0.001). Each additional utility/resource loss exposure was associated with a 2.3 percentage-point increase in the probability of any anxiety disorder (P = 0.001). Each additional unsanitary/hazardous exposure was associated with a 1.9 percentage-point increase in the probability of any mood disorder (P = 0.017). Findings varied when individual disorders were examined. No associations were found between exposures and substance use disorders.
Conclusions
Utility/resource losses and unsanitary/hazardous conditions emerged as important correlates of post-disaster psychiatric disorders, suggesting that these often-overlooked exposures should be incorporated into disaster assessments and recovery planning.
Mental disorders are intergenerationally associated, particularly affecting adolescent offspring. However, the extent of such intergenerational associations among adult women in China remains unclear. This study aimed to examine the intergenerational associations of depression and anxiety between two adult female generations.
Methods
This cross-sectional study included 2,130 grandmother-mother dyads from the Grandmothers, Mothers, and Their Children’s Health study. Depression and anxiety of the grandmaternal (G0) and maternal (G1) generations were assessed using the 10-item version of the Center for Epidemiologic Studies Depression Scale and the 7-item Generalized Anxiety Disorder Scale, respectively, with scores of 10 or higher defined as depression and anxiety. Statistical analyses included logistic regression, negative binomial regression, and restricted cubic spline analyses.
Results
A total of 11.4% G0 and 11.5% G1 participants reported depression, and 4.1% G0 and 3.1% G1 participants reported anxiety. Depression in G0 was associated with 4.29-fold (95% CI: 3.09–5.94) and 3.50-fold (95% CI: 1.98–6.01) higher odds of depression and anxiety in G1, respectively, while anxiety in G0 was associated with 3.95-fold (95% CI: 2.41–6.35) and 5.47-fold (95% CI: 2.64–10.60) higher odds of depression and anxiety in G1, respectively; dose–response relationships were also observed. In addition, the intergenerational association of depression was stronger among G0 participants residing in rural areas, whereas G0 depression and anxiety were more strongly associated with anxiety in G1 among those with higher household income.
Conclusions
Mental disorders were intergenerationally associated between mothers and their adult daughters. These findings emphasize the importance of family-based interventions for mental health.
Edited by
Liz McDonald, East London NHS Foundation Trust,Roch Cantwell, Perinatal Mental Health Service and West of Scotland Mother & Baby Unit,Ian Jones, Cardiff University
Millions of women and girls worldwide experience violence. Violence against women and girls takes many forms, including physical, emotional and sexual violence and abuse, which is associated with a range of adverse impacts on women, their families and society as a whole. Health professionals supporting women during the perinatal period should assess the risks posed by exposure to previous or current violence and how this may affect them during pregnancy. As an important risk factor in a woman’s mental health presentation, psychiatrists working with pregnant and postpartum women should consider the presence of violence in their formulation; it can increase the risk of anxiety, depression and post-traumatic stress disorder (PTSD). Domestic violence and abuse increase the risk of domestic homicide and may play a role in many perinatal suicides. Sensitive assessment and effective management of women exposed to violence can improve engagement with mental health services and response to treatment.
Dual disorder, comprising of substance use and mental health disorders, requires a comprehensive treatment approach. The most effective is integrated dual disorder treatment, which involves addressing both conditions concurrently by the same specialists and in the same setting. This study examines characteristics of integrated dual disorder care offered by treatment services across European countries.
Methods:
In 2022, representatives of 14 integrated care for dual disorder providers in 10 European countries were asked to respond to a survey about their treatment process, outcomes, barriers and facilitators when implementing dual disorder treatment in respective countries. Thematic qualitative analysis was used to explore closed- and open-ended responses, focusing on commonalities and differences between surveyed services.
Results:
Integrated care services varied in treatment settings and structure, but all offered comprehensive support for dual disorder. Among 14 services, half addressed tobacco addiction or provided suicide prevention, three treated cannabis use, and none accepted patients in opioid agonist therapy. Few services reported evaluating treatment outcomes in standardised way. Services supported patients with social security, employment, housing and education, but also noted difficulties in coordinating post-treatment care due to divergent views on dual disorder among specialists from different services.
Conclusions:
Integrated care services provide comprehensive and tailored support for people with dual disorder but remain distinct within the healthcare options available to this patient group across Europe. Existing and future integrated care services would benefit from addressing tobacco and cannabis use, measuring treatment outcomes and improving continuity of care.
The awareness of climate change as a global environmental threat through media consumption and/or social interaction can have a psychological impact on people’s mental health. However, little is known about the association between climate change awareness-related psychological distress (CCARPD) and mental health in people with psychiatric diagnoses or subclinical symptoms.
Methods
A comprehensive and systematic literature search of the PubMed, Embase, Web of Science Core Collection, Scopus, and CENTRAL electronic databases (from inception to February 2025) was conducted, without language restriction, for articles assessing the association between CCARPD and the mental well-being of people in the general and psychiatric populations.
Results
Twenty-eight thousand forty-seven reports were retrieved. Of these, 67 met the inclusion criteria (64 general and 3 psychiatric population studies). The overall correlation between CCARPD and mental health measurements (ranging from subclinical symptoms to clinical diagnoses of depression, anxiety, or stress) was positive and of weak-to-moderate strength. Nevertheless, higher psychological distress due to the awareness of climate change was found in those having more severe mental health problems.
Conclusions
Although most studies have found small-to-moderate correlations between CCARPD and mental health measurements, it can be distressing and damaging for those with more severe mental health problems. As CCARPD will increase globally as the climate crisis unfolds in the coming decades while the understanding of the connections between CCARPD and mental well-being is still at an early stage of development, more research will be of utmost relevance, particularly in psychiatric populations.
Despite the high prevalence of mental disorders, knowledge about mental health, its promotion, prevention, and pathways to care in the general population remain limited. Mental Health First Aid (MHFA) seeks to increase mental health literacy in the general population and enable individuals to support others with mental health problems until professional help is available. This study aimed to investigate the feasibility and initial effects of MHFA training on (i) mental health literacy, (ii) stigmatizing attitudes toward individuals with mental health problems, (iii) social distance, (iv) trainees’ mental health, and (v) quality of life.
Methods
In an uncontrolled pilot study, individuals aged 18–75 years who participated in MHFA courses in Germany were recruited. Outcomes were assessed at baseline, post-training, and 6-month follow-up.
Results
In total, 362 participants (mean age 43 years, 78% female) enrolled in the study at baseline. Retention was about 50% for post-training and 60% for follow-up assessment. At post-training, mental health literacy was increased (adjΒ = 6.77, 95% CI = 5.69 to 7.84) and social distance (adjΒ = −2.30, 95% CI = −2.73 to −1.87) and stigmatizing attitudes (adjΒ = −2.61, 95% CI = −3.25 to −1.97) were reduced. These effects were also evident at 6-month follow-up. There were no effects on trainees’ mental health. At the 6-month follow-up, 89% of trainees had talked to someone with mental health problems at least once, and 65% of trainees were quite or very confident in offering help.
Conclusions
Our findings suggest initial beneficial effects of MHFA training as implemented in Germany. A randomized controlled trial of MHFA in Germany is now warranted.
This study explored the association between serotonin transporter gene (5HTTLPR) and brain-derived neurotrophic factor gene (BDNF) polymorphisms with mental health disorders in a Chilean primary care population using latent class analysis. The sample included 789 adults genotyped for 5HTTLPR and BDNF, who were assessed for psychiatric diagnoses using the Composite International Diagnostic Interview (CIDI). Two distinct mental health profiles emerged: a high psychiatric comorbidity group, marked by a high prevalence of anxiety and stress-related disorders, and a low comorbidity group. The study found that the L’/L’ polymorphism of the serotonin transporter gene was associated with a reduced risk of belonging to the high-comorbidity group, particularly when paired with the GG polymorphism of the BDNF gene. These findings suggest a synergistic interaction between these genes that influences susceptibility to psychiatric disorders. This research underscores the importance of considering genetic interactions in mental health studies and highlights the utility of latent class analysis in identifying clinically relevant diagnostic profiles, which could enhance early detection and intervention strategies in primary care.
Individuals with childhood experience of out-of-home care (OHC) face elevated risks of criminal behavior and poor mental health compared with the majority population. Evidence on how trajectories of offending and psychiatric disorders covary among individuals with experience of OHC is needed. This study is based on a cohort of 14,608 individuals (n = 1,319 with OHC experience) born in the Stockholm metropolitan area in 1953 (49% women) from birth to age 63 (2016). Group-based multi-trajectory modeling among those with at least one offense or psychiatric disorder (40.5% of the men, 16.6% of the women) identified four co-occurring trajectories for both sexes. Multinomial regression analyses showed that adolescent OHC placement, particularly in institutions and for behavioral reasons, was linked to higher odds of early-adulthood-limited or decreasing offending and psychiatric trajectories. Most individuals recover from offending and psychiatric disorders by retirement, but placed individuals in particular remain at high risk for offending, alongside psychiatric disorders, throughout early adulthood. Early assessment and tailored attention to needs and risk levels is important when designing long-term care services to mitigate this. Research on underlying mechanisms, and on collaboration between the welfare, justice, and psychiatric care systems, can help to design effective intervention strategies and policies.
Little is known about the diagnostic trajectories following a first psychiatric diagnosis in childhood or adolescence. Such knowledge could aid clinicians in treatment, risk prediction, and psychoeducation. This study presents a comprehensive nationwide overview of diagnostic trajectories in children and adolescents after their first diagnosis in child and adolescent psychiatric hospitals.
Methods
Patients aged 0 to 17 years who received their first psychiatric diagnosis between January 1996 and December 2011 were identified through the Danish National Patient Registries. Shifts at the International Classification of Diseases (ICD-10) two-cipher level (F00-F99), grouped into 19 categories, were identified. Subsequent diagnoses during 10 years of follow-up until December 2021 were identified and analyzed using state sequence analysis and Cox proportional hazard regression models.
Results
A total of 77,464 children and adolescents (32,733 [42.26%] girls) were identified with a first-time psychiatric diagnosis. Among these, 46.7% of girls and 37.6% of boys had at least one diagnostic shift after 10 years of follow-up. High entropy and low diagnostic stability were found in first-time diagnoses often presenting in adolescence, such as affective disorders, psychotic illness, and personality disorders, while lower entropy and high diagnostic stability were found in neurodevelopmental disorders and eating disorders. For most categories, girls had higher mean entropy measures than boys (P < 0.05).
Conclusions
Diagnostic shifts are common in child and adolescent psychiatric services, particularly when the first contact occurs in adolescence. Adequate focus on psychoeducation about emerging diagnostic shifts, and on timely detection, particularly in girls, and particularly in adolescence, is warranted.
Chapter 6 identifies the doctrine of diminished responsibility as the closest antecedent of the Universal Partial Defence (UPD), and a suitable template from which to forge the proposal. Taking a particularised theoretical approach, the chapter draws on case law and empirical studies to arrive at a more fine-grained account of the operation of the defence. It reveals a penumbral approach to its interpretation in the courts, through the subtle inclusion of factors that sit at the edge of what might be considered a recognised medical condition or mental disorder. The chapter maintains that this flexibility suggests a stomach for moral complexity on the part of fact-finders, arguing for a broader, normative test that can include consideration of circumstance, as the basis of the UPD. The analysis considers the role of key decision-makers, and it serves to inform the development of a bounded causal theory of partial excuse in Chapter 7.
This chapter explores legislative time limits on the prosecution of crime in civil and common law jurisdictions. It addresses the rationales for barring the prosecution of old crimes and undertakes a comparative analysis of three jurisdictional groupings: Continental Europe (with a focus on Germany and France), the Commonwealth (with a focus on England and Wales) and the United States (with a focus on federal law). The analysis identifies comparable features in limitation doctrine across jurisdictions while revealing how the theory and practice of statutes of limitation differs markedly in different legal systems. In broad terms, Continental systems codify general and categorical time limits on the prosecution of offences; Commonwealth systems tend not to have any statutory time bars on the prosecution of offences other than minor offences; and in the United States, most offences, other than the most serious, are subject to statutory limitation periods. The chapter concludes by drawing together the points of comparison between the three jurisdictional groupings, commenting on their distinctions and similarities.
There are no such things as “personality disorders” distinct from other mental disorders. Distinct personality disorders cannot be identified based on their developmental course or their symptoms. The new ICD and DSM concept of personality disorder as self and interpersonal dysfunction identifies important forms of psychopathology but is not more (or less) related to personality than are other disorders. Rather, personality traits contribute to risk for all forms of mental disorder, and most symptom dimensions are coextensive with dimensions of normal personality, such that persistent symptoms of psychopathology are typically extreme or maladaptive variants of normal personality traits. However, symptoms are merely indicators of risk rather than necessary and sufficient indicators of psychopathology. We draw on our cybernetic dysfunction theory of psychopathology to clarify the role of personality in mental disorder. Psychopathology is defined as “persistent failure to move toward one’s goals, due to failure to generate effective new goals, interpretations, or strategies when existing ones prove unsuccessful.” Personality is exhaustively described by personality traits and characteristic adaptations, the latter being relatively stable goals, interpretations, and strategies that are specified relative to an individual’s particular life circumstances. Psychopathology always involves failure of characteristic adaptations and thus breakdown in personality functioning.
Madness, as a form of suffering, has existed as long as humankind. Only in the nineteenth century did it come under the aegis of medicine, giving rise to the birth of psychiatry/alienism as a discipline. Prior to this, madness had attracted the attention of many agents, including the Church, medics, philosophers, and others. During the seventeenth century in the context of secularization, the scientific revolution, and other factors, it began to be viewed as a natural kind and thereby a medical object. In the nineteenth century, the medicalization of madness was further associated with a growth of mental asylums, enabling alienists to observe patients longitudinally, to classify their complaints, and to construct the language for the description/construction/capture of mental symptoms, namely, descriptive psychopathology. In contrast to the signs available to medical doctors, alienists had to develop different clinical criteria, and the emerging social sciences became the natural source for these. Thus, from the beginning, descriptive psychopathology was a hybrid construct, incorporating the frameworks of both the natural sciences and the social sciences. The tension resulting from this incongruent union has persisted ever since and contributed to the polarities in current conceptions of mental disorders as well as the challenges facing psychiatry today.
Current empirical understanding of the relationship between psychopathology and terrorist behaviours in women is limited, because most research focuses on male perpetrators and relies on secondary sources. Addressing this gap is crucial, particularly given previous research that highlights significant differences in mental health problems between women and men involved in non-terrorist violent activities.
Aims
To empirically examine the presence of psychopathology in women exhibiting terrorist behaviours, as well as its potential role in these behaviours.
Method
A case series study of 14 Dutch female convicts associated with the (so-called) Islamic State of Iraq and Syria (ISIS), examining the occurrence and types of mental disorders, psychopathological problems and pathological personality traits, and exploring their potential role in terrorist behaviours based on forensic mental health reports from psychiatrists and psychologists.
Results
Half of the women (n = 7) exhibited mental disorders during terrorist activities, primarily personality disorders. Psychopathological problems included susceptibility to influence (71%, n = 10), identity problems (64%, n = 9), feelings of inferiority (57%, n = 8) and naivety (50%, n = 7). A significant link between terrorism and mental disorders, psychopathological problems or pathological personality traits was identified in almost half of the women (43%, n = 6).
Conclusions
Psychopathology is present in some women involved in terrorist behaviours, influencing their involvement, but is absent or irrelevant in others. Identifying psychopathology in women with terrorist tendencies is essential for early prevention and should be a core competency for psychiatrists.
Several studies have used a network analysis to recognize the dynamics and determinants of psychotic-like experiences (PLEs) in community samples. Their synthesis has not been provided so far. A systematic review of studies using a network analysis to assess the dynamics of PLEs in community samples was performed. Altogether, 27 studies were included. The overall percentage ranks of centrality metrics for PLEs were 23.5% for strength (20 studies), 26.0% for betweenness (5 studies), 29.7% for closeness (6 studies), 26.9% for expected influence (7 studies), and 29.1% for bridge expected influence (3 studies). Included studies covered three topics: phenomenology of PLEs and associated symptom domains (14 studies), exposure to stress and PLEs (7 studies), and PLEs with respect to suicide-related outcomes (6 studies). Several other symptom domains were directly connected to PLEs. A total of 6 studies investigated PLEs with respect to childhood trauma (CT) history. These studies demonstrated that PLEs are directly connected to CT history (4 studies) or a cumulative measure of environmental exposures (1 study). Moreover, CT was found to moderate the association of PLEs with other symptom domains (1 study). Two studies that revealed direct connections of CT with PLEs also found potential mediating effects of cognitive biases and general psychopathology. PLEs were also directly connected to suicide-related outcomes across all studies included within this topic. The findings imply that PLEs are transdiagnostic phenomena that do not represent the most central domain of psychopathology in community samples. Their occurrence might be associated with CT and suicide risk.
There is an unprecedented societal focus on young people’s mental health, including efforts to expand access to child and adolescent mental health services (CAMHS). There has, however, been a lack of research to date to investigate adult mental health outcomes of young people who attend CAMHS.
Methods
We linked Finland’s healthcare registries for all individuals born between 1987 and 1992. We investigated mental disorder diagnoses recorded in specialist adult mental health services (AMHS) and both inpatient and outpatient service use by age 29 (December 31, 2016) for former CAMHS patients.
Results
Before the end of their 20s, more than half (52.4%, n = 21,183) of all CAMHS patients had gone on to attend AMHS. The most prevalent recorded adult psychiatric diagnoses received by former CAMHS patients were depressive disorders (30%, n = 11,768), non-phobic anxiety disorders (21%, n = 7,910), alcohol use disorders (9.5%, n = 3,427), personality disorders (9.3%, n = 3,366), and schizophrenia-spectrum disorders (7.6%, n = 2,945). In the total population, more than half of all AMHS appointments (53.1%, k = 714,239/1,345,060) were for former CAMHS patients. More than half of all inpatient psychiatry bed days were for former CAMHS patients (53.1%, k = 1,192,991/2,245,247).
Conclusion
While there is a strong focus on intervening in childhood and adolescence to reduce the burden of mental illness, these findings suggest that young people who receive childhood intervention very frequently continue to require specialist psychiatric interventions in adulthood, including taking up a majority of both outpatient and inpatient service use. These findings highlight the need for a greater focus on research to alter the long-term trajectories of CAMHS patients.
Mounting evidence suggests that the Mediterranean diet has a beneficial effect on mental health. It has been hypothesised that this effect is mediated by a variety of foods, nutrients and constituents; however, there is a need for research elucidating which of these components contribute to the therapeutic effect. This scoping review sought to systematically search for and synthesise the research on olive oil and its constituents and their impact on mental health, including the presence or absence of a mental illness or the severity or progression of symptoms. PubMed and OVID MEDLINE databases were searched. The following article types were eligible for inclusion: human experimental and observational studies, animal and preclinical studies. Abstracts were screened in duplicate, and data were extracted using a piloted template. Data were analysed qualitatively to assess trends and gaps for further study. The PubMed and OVID MEDLINE search yielded 544 and 152 results, respectively. After full-text screening, forty-nine studies were eligible for inclusion, including seventeen human experimental, eighteen observational and fourteen animal studies. Of these, thirteen human and four animal studies used olive oil as a comparator. Observational studies reported inconsistent results, specifically five reporting higher rates of mental illness, eight reporting lower and five reporting no association with higher olive oil intake. All human experimental studies and nine of ten animal studies that assess olive oil as an intervention reported an improvement of anxiety or depression symptoms. Olive oil may benefit mental health outcomes. However, more experimental research is needed.