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Sleep disturbances are highly prevalent in individuals with severe mental illness (SMI) and are associated with functional impairment. This study examined the prevalence of sleep disturbances and their associations with psychiatric symptoms and functional outcomes in a transdiagnostic SMI sample.
Methods
In this cross-sectional study, SMI outpatients completed standardized assessments of sleep disturbances (PSQI, ISI, STOP-Bang, ESS, SQ-RLS, and SQ-RBD), psychiatric symptoms (HARS, MADRS, YMRS, PANSS-N, and CGI-S), and functioning (FAST). Bivariate analyses were followed by structural equation modeling (SEM), including latent constructs for insomnia and depressive/anxious symptoms to estimate direct and indirect associations with functional impairment.
Results
A total of 229 participants were included, and 69% screened positive for at least one sleep measure, including poor sleep quality (55.5%). Among the specific sleep-related problems, high risk of obstructive sleep apnea (OSA) (45.8%) was the most prevalent. Sleep disturbances were associated with greater clinical severity and worse functional impairment. In the SEM, depressive/anxious symptoms (β = 0.45), negative symptoms (β = 0.38), manic symptoms (β = 0.17), and OSA risk (β = 0.41) were independently associated with functional impairment. Insomnia exhibited an inconsistent pattern, with a negative direct effect (β = −0.47) and a positive indirect effect on functional impairment through depressive/anxious symptoms (β = 0.22).
Conclusions
Sleep disturbances are highly prevalent in individuals with SMI and are associated with functional outcomes, particularly insomnia and OSA risk. Systematic screening for sleep disturbances in psychiatric care may help identify clinically relevant and potentially modifiable factors associated with functional impairment.
There are various statistical models with different features and assumptions in meta-analysis. Popular models include the fixed-effect (or common effect), random-effects, and mixed-effects models. Apart from these models, several alternative models, such as the multiplicative error model (also known as the unrestricted weighted least squares model), the hybrid of additive and multiplicative error models, and the location-scale model, have been proposed in the literature. Understanding these models can be challenging for researchers without a solid mathematical background. Implementing or modifying these models is even more challenging for researchers unless they have advanced statistical and programming knowledge. This tutorial elucidates a structural equation modeling (SEM) framework to understand these models. Several R packages are introduced to facilitate the specification and generation of graphical models for these meta-analytic models. Researchers may fit these models with the full information maximum likelihood estimation method. This holds significant potential across two domains. First, it can be used as an educational tool in teaching and learning meta-analytic models. Second, the framework supports the development and evaluation of novel meta-analytical models, which have not yet been implemented in current meta-analysis software, thereby fostering advancements in meta-analytic methods. This tutorial also demonstrates, using two real datasets, how to extend it to address research questions involving complex meta-analytic data. Limitations and future directions to extend the SEM-based meta-analysis are discussed.
Due to the indeterminacy problem in factor analysis, factors are not uniquely determined by observed data. We investigate the consequences of this problem for the interpretation of simulation studies and for linear structural equation models. For simulation procedures, factor indeterminacy implies that as long as the simulated data have the correct covariance matrix, there exists a possibly large space of factors and error terms that can generate the simulated data via the model equations. For linear structural equation models, the linearity of the structural part of the model is only partly testable by the distribution of the data. Practical recommendations for conducting simulation studies are provided. We give numerical illustrations, including a case where the observed data are normal and fit a linear structural equation model perfectly, yet are generated by a highly non-linear structural equation model.
By building knowledge in a deliberate and systematic manner, we can gain a more complete understanding of a given research area relevant to corpus linguists. Specifically, empirically informed hypotheses (i.e., hypotheses that result from a synthesis of findings from all relevant prior studies) play a key role in this endeavor in that they enable us to test to what extent generalizations from previous research are consistent with our results, or if we need to make adjustments to our existing knowledge or theory. In this Element, we aim to provide a practical and accessible introduction to select statistical methods for evaluating such empirically informed hypotheses. In particular, we illustrate techniques from the broader null-hypothesis significance testing framework (e.g., equivalence testing), and structural equation modeling framework (e.g., measured variable path analysis), with the goal of encouraging knowledge building in a more principled and systematic manner in corpus linguistics.
The autoregressive latent trajectory (ALT) model was introduced at the 1999 Psychometric Society meeting. Over the past 25 years, ALT models have become widely used for studying longitudinal dynamics, especially changes in multiple variables over time. Yet, their popularity has also generated confusion. Some published claims are contradictory, others are factually incorrect, and many emphasize the need for clearer explanations of the classic and latent-variable ALT (LV-ALT) models. This article explains the assumptions and structure of ALT models and clarifies how their parameters should be interpreted. It also supports both between- and within-component interpretations—contrary to assertions that such interpretations are impossible. We review prior literature on ALT properties and assess their accuracy. Further, we show the broad range of longitudinal models that are special cases of ALT models, enabling researchers to test and select the most suitable models for their data. An empirical example, used in multiple studies, illustrates these points. Overall, ALT and LV-ALT models provide a unifying framework for comparing many common longitudinal models. By clarifying their properties, correcting misconceptions, and demonstrating their applications, we aim to help researchers choose models that best reflect their theories and data.
This quantitative study develops and validates a novel Culturally Responsive Blended Learning Success (CR-BLS) model for evaluating technology-enhanced EFL instruction effectiveness in collective educational contexts. Conducted at a Chinese university, the research examined an intelligent blended learning ecosystem integrating three widely adopted platforms (U-Campus, GradingNet, and Learning Hub) for content delivery, assessment, and collaboration in College English instruction. The CR-BLS model extends a widely recognized seven-factor quality framework by integrating three culturally grounded moderators: hierarchical teacher–student relationships, collective learning orientation, and examination-driven motivation. The proposed model was empirically validated through data collection from 1,816 non-English major undergraduates engaged with the blended learning ecosystem using partial least squares structural equation modeling (PLS-SEM). Results revealed that the proposed quality factors explained 71.4% of the variance in perceived satisfaction, 54.2% in perceived usefulness, and 34.1% in system use. Learner quality and instructor quality significantly influenced both perceived satisfaction and usefulness, while educational system quality primarily affected system use. Furthermore, perceived usefulness, satisfaction, and system use collectively accounted for 64.7% of the variance in perceived learning benefits. Cultural moderators demonstrated significant influence on the relationships between quality dimensions and learning outcomes, enhancing the proposed model’s contextual validity for collective educational environments. This study contributes to both theoretical advancement and practical implementation of blended learning systems in collective educational settings.
Neuropsychological (NP) tests are multi-domain in execution. Reliance on a single score representing specific domains obscures the detection of subtle cognitive changes and increases risk of inaccurate assessment. Rooted in the Boston Process Approach (BPA), the Framingham Heart Study (FHS) captures multi-dimensional errors and process features within and across NP tests. We examined these BPA variables in community-dwelling older adults.
Methods:
We analyzed data from 2363 dementia-free participants aged 60 and above. Exploratory and confirmatory factor analyses used Kemeny covariance structures. Measurement invariance was estimated across age, sex, and education groups. We assessed the impact of demographics on latent factors, and the ability of these factors to predict future conversion to all-cause dementia. We trained machine learning (ML) models to compare NP and BPA data.
Results:
Participants were older adults (mean age 71.5 ± 8.7 years), primarily female (54.2%), and non-Hispanic White (96.5%). The bifactor model was the only model with adequate fit (CFI = 0.96, RMSEA = 0.03). General and specific factors captured ability for accurate and strategic responses, test-specific variance, and nuanced executive and semantic processes distributed across tests. Higher general ability and stronger verbatim story recall were associated with a reduced likelihood of developing all-cause dementia (general: OR = 0.15, 95% CI [0.12–0.86]; recall: OR = 0.24, 95% CI [0.23–0.90]) over a median of 5.2 years. With NP/BPA data, ML models identified >99% of 222 converters.
Conclusions:
This study highlights the strengths of NP/BPA data. Multidimensional cognitive features may enhance sensitivity to early changes predictive of incipient dementia.
Parthenium weed (Parthenium hysterophorus L.) is rapidly invading southern Oman, posing growing challenges to agricultural productivity and rural livelihoods in Dhofar’s crop–livestock systems. This study assesses its agronomic and socioeconomic impacts using field surveys and a stratified household survey of 40 farms conducted between June and August 2022. Data were analyzed using partial least-squares structural equation modeling (PLS-SEM) to examine the relationships between farmer characteristics, infestation levels, weed management practices, and farm revenue. Results indicate that while most farmers are aware of P. hysterophorus, limited recognition at early growth stages delays control and increases management costs. Education (β = 1.009, P = 0.06), cultivated area (β = 1.033, P = 0.003), and chemical control expenditures (β = 0.295, P = 0.05) were positively associated with gross revenue, whereas age had a negative effect (β = −0.762, P = 0.08). Infestation significantly increased labor-intensive weeding costs (β = 2.072, P = 0.07) but reduced chemical use (β = −1.303, P = 0.032), indicating substitution toward manual control. Although time spent uprooting parthenium reduced infestation levels (β = −0.128, P < 0.001), it also increased weeding and chemical control costs, highlighting the financial burden of relying on manual methods. Crop-specific analysis showed heterogeneous vulnerability, with peas (Pisum sativum L.) more affected than wheat (Triticum aestivum L.) and tomato (Solanum lycopersicum L.). Overall, the findings demonstrate that parthenium imposes measurable income and welfare risks on farming households. These impacts can be mitigated through farmer education, early detection, and judicious chemical use within an integrated weed management framework. Strengthening extension services and promoting crop-specific interventions are essential for protecting rural livelihoods and food security in arid, invasion-prone farming systems.
David Collier’s work on measurement validity and methods of validation establishes a baseline understanding that still largely describes the state of theory and practice. Scholars have developed some new ideas, and real-world conditions have changed in ways that shift the picture in subtle but important ways, but the road map that Collier’s work set up remains a useful guide to the landscape. There may well be sufficient differences between the ethnographic and interpretive measurement methods that have gained intellectual ground in recent years, in comparison with the more established case-based tradition, to potentially divide the tradition in two. The availability of large, complex data sets through digital distribution pushes scholars toward statistical techniques and, in particular, toward more generalized measurement hypotheses – a trend that leads to good research but also produces some losses. There may be opportunities for research that brings case-based techniques back in to ground these methods in more specificity, although the challenge of how to do this efficiently will demand serious methodological work. Finally, the text-as-data tradition shows scholars who have run ahead of the methodological literature in terms of mixing methods across measurement traditions and the qualitative/quantitative divide.
Structural equation modeling (SEM) is a flexible statistical technique with multiple applications, including behavioral genetics and social sciences. Building on the original design of the umx package, which improved accessibility to OpenMx by specifying a concise syntax, umx v4.5 extends functionality for longitudinal and causal twin designs while improving interoperability with graphical modeling tools such as Onyx. New capabilities include: classic and modern cross-lagged panel models; Mendelian Randomization Direction-of-Causation (MR-DoC) twin models incorporating polygenic scores as instruments; support for definition variables directly in umxRAM(); a workflow for importing paths from Ωnyx; a dedicated function for incorporating censored variables’ data into models, particularly valuable in biomarker research; improved covariate placeholder handling for definition variables; sex-limitation modeling across five twin groups, accommodating quantitative and qualitative sex differences; and covariate residualization in wide- or long-format data. These new functionalities accelerate reproducible, reliable, publication-ready twin and family modeling, and integrated journal-quality reporting, thereby lowering barriers to genetic epidemiological analyses
Childhood trauma is common in functional motor disorder (FMD), but it is unclear whether specific trauma dimensions are differentially linked to symptom burden, and whether depression, anxiety, or multimorbidity can mediate these associations.
Methods
We conducted a cross-sectional case–control study including 322 patients with clinically definite FMD and 215 neurologically healthy controls, balanced with respect to age and sex. Six outcomes – motor symptom severity, cognitive complaints, depression, anxiety, fatigue, and pain – were jointly modeled using Bayesian multivariate regression with Childhood Trauma Questionnaire subscales as predictors. Bayesian structural equation modeling tested mediation by depression, anxiety, and multimorbidity.
Results
In FMD, emotional abuse was the most consistent trauma correlate, associated with higher depression (β = 0.37, 95% CrI 0.22–0.51), anxiety (β = 0.32, 95% CrI 0.16–0.47), cognitive complaints (β = 0.27, 95% CrI 0.11–0.42), fatigue (β = 0.17, 95% CrI 0.03–0.32), and motor symptom severity (β = 0.15, 95% CrI 0.04–0.25). Mediation analyses indicated that affective symptoms fully accounted for trauma–symptom associations (indirect effect β = 0.42, 95% CrI 0.27–0.56). Multimorbidity was associated with more severe affective symptoms (β = 0.24, 95% CrI 0.12–0.37) and FMD symptoms (β = 0.24, 95% CrI 0.07–0.42) but did not mediate trauma–symptom relationships.
Conclusions
Emotional abuse is a key developmental risk factor for FMD, with its effects on symptom severity mediated by depression and anxiety. Multimorbidity increases symptom burden but is not a primary pathway linking trauma to FMD. Findings support routine trauma and affective symptom screening in FMD and targeted psychotherapeutic interventions.
Parental alcohol supply in early childhood may increase the risk of alcohol use in late adolescence. This study examined its longitudinal impact and the distinct roles of mothers’ and fathers’ drinking.
Methods
We studied 1,891 mother–child pairs from the Czech European Longitudinal Study of Pregnancy and Childhood. Mothers reported parental alcohol supply at ages 3, 5, 7, and 11 years, while adolescent alcohol use was reported by mothers, pediatricians, and youth at ages 18 and 19 years. Structural equation modeling assessed the longitudinal link between early alcohol supply (three classes: none, occasional, and frequent) and adolescent alcohol use, accounting for parental drinking and covariates, including the child’s sex, mother’s education, and family structure.
Results
Alcohol supply began in early childhood, with 14% of children exposed by age 3 and around 20% by age 11. By age 19, one-third of individuals reported frequent alcohol use. Adolescents’ alcohol use was associated with concurrent mothers’, but not fathers’ alcohol use (β = .24, p < .001). Early alcohol supply predicted higher adolescent use for both occasional (β = .14, p = .041) and frequent (β = .22, p = .005) classes. Mothers’ and fathers’ alcohol use at 6 months was associated with frequent alcohol supply, and fathers’ alcohol use was also associated with occasional alcohol supply. Significant indirect effects were found from early parental drinking to adolescent use via these classes.
Conclusions
Public health messaging should emphasize the risks of early alcohol consumption, including its potential harm to the developing brain.
Structural equation modeling (SEM) is a powerful and flexible modeling framework for testing complex relationships among observed and latent variables. However, its methodological complexity and analytical flexibility also increase the risk of questionable research practices (QRPs), especially in fields like applied linguistics, where training in advanced statistics may be limited. This article synthesizes the literature on QRPs and applies it to SEM by identifying seven categories of problematic practices: not checking assumptions, not validating a measurement model, not testing competing models, not sufficiently justifying modeling decisions, relying on post hoc model modification, overemphasizing global fit indices, and incomplete or nontransparent reporting. Each practice is described with examples and linked to broader issues in research ethics and transparency. The paper concludes with concrete recommendations for improving the credibility and reproducibility of SEM research, emphasizing the integration of best practices with the principles of open science.
Cyber disinformation is a global, very sophisticated phenomenon, capable of producing negative consequences on democratic values and institutions. This chapter argues that individual behavior of users plays a key role in the control of the phenomenon and aims to identify factors that impact on users’ behavioral intentions and cyber hygiene behavior. This chapter integrates the Extended Theory of Planned Behavior and a Structural Equation Model, realized through Partial Least Square – –Structural Equation Modeling, applied to the cyber disinformation phenomenon. The research data were collected using a questionnaire administered in Poland and Romania and analyzed using the Structural Equation Model. The model’s parameters were processed using the SmartPLS software. The reliability of the variables was assessed using Cronbach’s Alpha and Composite Reliability. The research revealed the applicability of the Theory of Planned Behavior model and found that Moral Norms and Perceived Behavioral Control have an impact on Behavioral Intention and Cyber Hygiene Behavior. The findings of this chapter can provide stakeholders with important insights that can lead to improved responses to the phenomenon.
Due to certain developments in the business of fundraising, there exists an increasing necessity to theoretically and empirically analyze donor behavior. This article examines donor retention from the donor’s point of view. It concretizes four antecedents and their relationships with one another. The influencing variables investigated are commitment, trust, satisfaction, and involvement. The empirical analysis conducted in Germany among donors of four representative social non-profit organizations shows that all variables have an influence on donor retention, although some of them only indirectly.
Chapter 5 provides an overview of numerous quantitative approaches to analyzing dyadic data, both cross-sectionally and longitudinally. We begin with a focus on models that address research questions about self and partner influence, such as the actor-partner interdependence model (APIM), and then highlight models that allow researchers to analyze variables that are dyadic in nature, such as the common fate model (CFM). We then explore models that are particularly well-suited to data that are micro-level in measurement, such as daily diary data, including grid sequence analysis. We include approaches to examining congruence and similarity within dyads, and end with important caveats about measurement invariance and structural equation modeling versus multilevel modeling approaches.
This chapter expands on traditional parametric and nonparametric methods by introducing generalized linear models (GLMs) and generalized linear mixed models (GLMMs), which broaden statistical analysis in applied linguistics research. GLMMs, for example, enhance traditional methods by incorporating both fixed and random effects, allowing researchers to account for predictors and grouping factors like subjects or items. This makes GLMMs particularly useful for analyzing complex, hierarchical data in linguistics studies. The chapter introduces linear mixed models (LMMs) before diving into GLMMs, highlighting their advantages in handling complex linguistic data. Practical examples and step-by-step instructions for conducting GLM and GLMM analyses using SPSS are provided, ensuring hands-on experience. Additionally, the chapter briefly overviews advanced multivariate tests, such as factor analysis, path analysis, structural equation modeling (SEM), and introduces Bayesian statistics. While not explored in depth, these methods are presented to underscore their significance in applied linguistics research and encourage their use when appropriate.
Childhood trauma is a well-established risk factor for psychosis, paranoia, and substance use, with cannabis being a modifiable environmental factor that exacerbates these vulnerabilities. This study examines the interplay between childhood trauma, cannabis use, and paranoia using standard tetrahydrocannabinol (THC) units as a comprehensive measure of cannabis exposure.
Methods
Data were derived from the Cannabis&Me study, an observational, cross-sectional, online survey of 4,736 participants. Childhood trauma was assessed using a modified Childhood Trauma Screen Questionnaire, while paranoia was measured via the Green Paranoid Thoughts Scale. Cannabis use was quantified using weekly standard THC units. Structural equation modeling (SEM) was employed to evaluate direct and indirect pathways between trauma, cannabis use, and paranoia.
Results
Childhood trauma was strongly associated with paranoia, particularly emotional, and physical abuse (β = 16.10, q < 0.001; β = 16.40, q < 0.001). Cannabis use significantly predicted paranoia (β = 0.009, q < 0.001). Interactions emerged between standard THC units and both emotional abuse (β = 0.011, q < 0.001) and household discord (β = 0.011, q < 0.001). SEM revealed a small but significant indirect effect of trauma on paranoia via cannabis use (β = 0.004, p = 0.017).
Conclusions
These findings highlight childhood trauma as a primary driver of paranoia, with cannabis use amplifying its effects. While trauma had a strong direct impact, cannabis played a significant mediating role. Integrating standard THC units into psychiatric research and clinical assessments may enhance risk detection and refine intervention strategies, particularly for childhood trauma-exposed individuals.
Eating disorders (EDs) are particularly prevalent among young adult females. Previous research has shown that childhood trauma and reduced mentalizing abilities are involved in ED symptoms. The current study was aimed at testing the mediating effects of failures in mentalizing on the relationship between childhood trauma and ED risk among young adult females. The sample consisted of 409 Caucasian young adult females, aged between 18 and 30 years old (M = 23.45, SD = 2.76). The reported mean body mass index was within the normal range (M = 22.62; SD = 4.35). Self-report instruments were administered to assess the variables of interest. Structural equation modeling revealed that childhood trauma predicted increased failures in mentalizing (β = .36) and ED risk (β = .30), that failures in mentalizing predicted an increased ED risk (β = .35), and that the positive association between childhood trauma and ED risk was partially mediated by failures in mentalizing (indirect effect: β = .13). These findings suggest that ED symptoms might result from unprocessed and painful feelings embedded in child abuse and neglect. Clinical interventions focused at improving mentalizing abilities might reduce the ED risk among young adult females who have been exposed to childhood trauma.
The current meta-analytic structural equation modeling (MASEM) techniques cannot properly deal with cases where there are multiple effect sizes available for the same relationship from the same study. Existing applications either treat these effect sizes as independent, randomly select one effect size amongst many, or create an average effect size. None of these approaches deal with the inherent dependency in effect sizes, and either leads to biased estimates or loss of information and power. An alternative technique is to use univariate three-level modeling in the two-stage approach to model these dependencies. These different strategies for dealing with dependent effect sizes in the context of MASEM have not been previously compared in a simulation study. This study aims to compare the performance of these strategies across different conditions; varying the number of studies, the number of dependent effect sizes within studies, the correlation between the dependent effect sizes, the magnitude of the path coefficient, and the between-studies variance. We examine the relative bias in parameter estimates and standard errors, coverage proportions of confidence intervals, as well as mean standard error and power as measures of efficiency. The results suggest that there is not one method that performs well across all these criteria, pointing to the need for better methods.