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China’s aging population faces increased prevalence in mid- and later life depression, with married middle-aged and older women vulnerable due to disproportionate caregiving and socioeconomic stress. Although emotional contagion between partners is well-documented, pathways through which depressive symptoms spread between these spouses remain unclear. This study examines the directional predictive patterns of depressive symptoms, wives to husbands specifically, within middle-aged and older Chinese couples.
Methods
Using the 2011–2013 longitudinal data from the China Health and Retirement Longitudinal Study (CHARLS), we analyzed 2,578 heterosexual couples aged 45 years or older. Depressive symptoms were assessed at two time points using the 10-item Center for Epidemiological Studies-Depression scale (CES-D-10). Cross-lagged panel network (CLPN) modeling estimated temporal changes in predictive pathways of each spouse’s symptoms in the other’s, capturing intra-personal symptom interactions and inter-spousal predictive dynamics while comparing patterns between couples.
Results
Distinct symptom networks emerged for husbands and wives, with wives’ emotional states showing stronger cross-partner predictive associations, highlighting gender-specific patterns. Wives’ fearfulness emerged as a critical bridge symptom, significantly predicting increases in husbands’ depressive symptoms. Overall, significant cross-spousal spillover associations were observed; emotional contagion patterns were notably asymmetric, showing more pronounced symptom predictions from wives to husbands.
Conclusions
Findings indicate bidirectional associations of depressive symptoms with significant gender disparities in symptom dynamics among middle-aged and older couples, highlighting the necessity for gender-sensitive, relationship-focused research and interventions. Dyadic network analysis provides new insights into depression dynamics, advocating approaches addressing relational factors with individual symptoms in mental health strategies for China’s aging population.
Adherence to the planetary health diet index (PHDI) is associated with health benefits, but its relationship with depression, particularly the roles of dietary components and symptoms, remains poorly understood. We aimed to (1) compare PHDI component interrelationships between individuals with and without depression; (2) identify PHDI components most predictive of depression using machine learning and (3) identify bridge nodes connecting PHDI components with depressive symptoms. This cross-sectional study analysed data from 25 542 adults in the National Health and Nutrition Examination Survey 2005–2018. The PHDI was calculated from two 24-h dietary recalls. Depression was assessed with the Patient Health Questionnaire-9 with scores ≥10 indicating depression. We employed network analysis to compare dietary structures, an extreme gradient boosting (XGBoost) model interpreted using shapley additive explanations (SHAP) values to identify predictors and bridge network analysis to identify bridge nodes connecting the PHDI and depressive symptom communities. The PHDI network in the non-depressed group was more densely connected than in the depressed group. SHAP analysis of the XGBoost model identified non-starchy vegetables (PHDI2) and added sugars (PHDI14) as the most important predictors, with higher component scores associated with a lower predicted probability of depression. In the bridge network analysis, appetite problems (PHQ5) and depressed mood (PHQ2) emerged as the strongest bridge nodes between the PHDI and depressive symptom communities. A structured, plant-forward dietary pattern was associated with lower depression levels, with appetite problems and depressed mood identified as the bridge nodes between the PHDI and depressive symptom communities.
The literature on U.S. politics has firmly established an increase in polarization in Congress since the 1970s, arguing that cultural issues are especially polarizing, while economic issues remain less polarized. However, increasing disagreement over the importance of economic issues from welfare state spending to taxation raises the question whether economic discourse has slowly become more polarized, too. This paper investigates issue-level polarization based on issue attention in Congress using speech data and proposes a measurement approach that combines computational text analysis with network analysis. The approach uses speech similarity between individual representatives to construct political networks over time. It measures issue-level polarization within these networks by calculating modularity scores based on the Leiden community detection algorithm. The measurement strategy shows strong patterns of issue-level polarization. This paper makes three contributions. First, it demonstrates that polarization can be studied with text analysis combined with network data. Second, it shows that representatives in Congress increasingly talk about entirely different economic issues. Third, it provides an analytical framework to compare discursive polarization in speech with issue-level polarization.
Over recent decades, international trade has expanded significantly, increasing economic integration but also amplifying systemic vulnerabilities. Recent global shocks, such as the COVID-19 pandemic and the Russia–Ukraine conflict, have exposed the fragility of international trade systems, underscoring the need for analytical tools to enable timely, evidence-based trade policy. This paper introduces TERRA, an analytical framework created by the Italian National Institute of Statistics to support the monitoring and analysis of European trade patterns using official statistics. Using high-frequency Eurostat COMEXT data, TERRA integrates network-based representations and time series indicators to identify structural vulnerabilities, emerging concentrations, and changes in countries’ roles within trade networks. Beyond interactive monitoring, the framework supports advanced analytical extensions, including programmatic longitudinal analyses and model-based counterfactual analyses, designed to explore trade reallocation mechanisms under stylized supply shocks. The analytical potential of TERRA is shown through two case studies: electricity trade during the COVID-19 pandemic and weapons and ammunition trade during the Russia–Ukraine conflict. The findings demonstrate how network-based monitoring tools, grounded in official statistics, can effectively interpret complex trade dynamics and support evidence-based trade governance.
Suicide attempts arise from an environment of many interconnected psychosocial and other factors. Yet, the relationships between these factors have not been studied widely in low- and middle-income countries, where an estimated 73% of suicides occur. We aimed to identify the patterns and complexrelationships between the factors associated with suicide attempts. We conducted a network analysis on data from 25,761 school-going adolescents across12 low- and lower middle-income countries (LLMICs), obtained from the Global School-based Health Survey. Using Ising network analysis, we examined theinterrelationships between past-year suicide attempts and several factors; we estimated centrality measures and examined network stability usingbootstrapping. Suicide attempt prevalence was 11.8%. The network analysis identified three clusters: mental health, physical harm and behavioral factors. Suicide attempts showed strong conditional associations with drug use, bullying and worrying, while having close friends was a prominent protective factor.Behavioral factors: alcohol use, drug use and smoking were the most central nodes, showing the highest expected influence. This study provides novel insightsinto the interplay between factors associated with adolescent suicide attempts in LLMICs. Comprehensive interventions could focus on clustered risk factors,while empowering protective factors and addressing behavioral factors could conditionally attenuate other associations in the network.
How do spatial proximity, policy networks, and temporal dynamics interact to shape education policy diffusion across the American states and have these channels of influence changed over time? This study introduces an integrated framework combining spatial-X (SLX) estimation, exogenously constructed policy-pathway network exposure, and discrete-time survival models with policy-level random intercepts to decompose the relative contributions of geographic, relational, and temporal channels. Drawing on 10 education policies from the State Policy Innovation and Diffusion (SPID) database (1896–2017), with the policy-pathway network constructed from 714 non-education SPID policies to address within-domain endogeneity concerns, the analysis finds that geographic proximity and network exposure each predict adoption, although their relative importance has shifted across historical periods. For policies whose diffusion windows opened before 1970, geographic proximity is the dominant detectable channel; for policies opening after 1970, network exposure displaces geography. Spatial effects are detectable for K-12 policies but not for higher-education reforms, where statistical power is limited. A complementary spatial Durbin model on rapid-diffusion versus sequential-diffusion subsamples shows that contemporaneous (SAR) determination dominates for policies that diffuse in fewer than seven years, while temporally lagged (SLX) determination dominates for sequential-diffusion policies. A SPID-wide replication on 635 policies and 17,628 adoption events confirms both spatial signals across the broader policy landscape. These findings reveal how the institutional infrastructure connecting American states has evolved from geography-mediated to network-mediated channels, with implications for diffusion theory, methodological practice, and intergovernmental policy coordination.
South Korea has one of the highest suicide rates among Organisation for Economic Co-operation and Development countries, and lower happiness has been associated with suicidal ideation and suicide attempts in Korean populations. We aimed to estimate a nation-level item network of happiness, affect, personality and well-being evaluations in South Korea and to test whether this network differed by sex, income and generation.
Methods
We analysed 2020–2023 Korean Happiness Survey data from 64,531 respondents in South Korea; the network analyses used 61,675 complete cases. A Gaussian graphical model with Least Absolute Shrinkage and Selection Operator regularization estimated edges among happiness, affect, personality and well-being evaluations. Subgroup differences by sex, income and generation were assessed with permutation-based Network Comparison Tests.
Results
The network contained 199 of 435 possible edges (45.7%). The strongest affective and happiness-related pairwise connections included happiness-enjoyment, stress-tiredness, sadness-depression and depression-anger. Global strength did not differ significantly across the planned subgroup comparisons, but network structure differed by sex, income, Millennials and Generation Z (MZ) versus Generation X, and MZ versus Baby Boomers. In the income comparison, happiness was more negatively linked to the agreeableness item ‘generally trusting’ in the low-income network, whereas its link with time for hobbies was stronger in the high-income network. In the generational comparison, the happiness-stress edge differed between the MZ generation and Baby Boomers, whereas no happiness-connected edge survived false discovery rate correction for MZ versus Generation X. No happiness-connected edge differed significantly by sex.
Conclusions
In South Korea, happiness was most closely linked to enjoyment and embedded within tightly connected affective and evaluative domains. The subgroup differences were selective rather than global, suggesting that future work relevant to population well-being and suicide prevention may benefit from focusing on specific happiness-linked domains such as positive affect, stress-related ties, discretionary time and perceived future security.
Children in families navigating significant adversity often face co-occurring physical and mental health problems, which together can contribute to substantial marginalization across the life course. These children and their families may greatly benefit from targeted interventions to disrupt accumulating vulnerability, which requires empirical evidence on the underlying dynamics of adversity and health problems throughout childhood.
Methods
We investigated associations between childhood adversities (material deprivation, experiences of loss or threat of loss, and family dynamics) and hospitalizations for mental and physical health problems across four developmental periods among 11,978 children who experienced high rates of family adversity. We used data from the Danish Life Course (DANLIFE) register-based cohort study and applied cross-lagged networks models. Hospitalizations were identified through inpatient, outpatient, and emergency hospital contacts.
Results
We found clear evidence of reciprocal associations between childhood adversities and physical and mental health problems across childhood, alongside strong autoregressive effects within adversity and health domains, indicating vicious circles of reinforcing vulnerability. Conditional on high health problems in infancy, childhood adversity was not found to be associated with additional health problems throughout the rest of childhood. Child health problems were, however, positively associated with subsequent adversity across childhood.
Conclusions
Dynamics of childhood adversity and poor health give rise to complex reinforcing patterns of vulnerability over time. Our findings contribute to a better understanding of the emergence of vulnerability resulting from childhood adversity and poor health in children, highlighting the importance of embracing the complex nature of these emergent phenomena, both in research and intervention.
Suicide is a serious public health issue and the leading non-accidental cause of death among adolescents in Spain. Although a previous suicide attempt is the strongest risk factor for a new attempt, studies focused specifically on adolescent reattempters remain scarce. This study aims to identify modulating factors for suicide reattempts in a clinical adolescent population following an index attempt, using network analysis.
Methods
We recruited a total of 287 adolescents aged 12 to 17, treated in emergency services after a recent suicide attempt. Data collection involved structured clinical interviews and validated self-report questionnaires assessing sociodemographic, psychopathological, and behavioral variables. Our network analysis explored significant correlations (r ≥ 0.2) between variables and their relative influence on suicidal behavior, with a particular focus on reattempts (1-year follow-up).
Results
Variables related to emotional and behavioral difficulties, childhood trauma, and depressive symptoms were the most central and influential within the network. In contrast, suicide reattempts and their frequency appeared as peripheral nodes with no significant direct associations. Emotional abuse was associated with a higher total number of suicide attempts, and the Self-Awareness of Mental Health intervention was linked to a longer time before reattempt.
Conclusions
This study highlights the complexity of suicide reattempt risk factors in adolescents, emphasizing the importance of indirect interactions rather than isolated predictors. Incorporating standardized self-report tools may enhance clinical assessment and prevention strategies. Through network analysis, this research offers an innovative perspective to understand the multivariate nature of suicide risk in adolescent populations.
The symptoms of psychotic disorders do not exist in isolation, but interact with one another as part of a dynamic network. For example, hallucinations may worsen mood, which may exacerbate hallucinations, creating self-reinforcing cycles. These symptom interactions have been shown to lead to the onset and maintenance of disorders. Effective treatments should therefore not only reduce overall symptom severity, but also disrupt these pathological interactions. Although antipsychotics are known to reduce symptom burden, their effects on the dynamic architecture of symptom networks remain unclear.
Aims
This study aims to characterise how 6 weeks of antipsychotic treatment alters the structure of temporal symptom networks in schizophrenia.
Method
Data were pooled from 8 randomised controlled trials evaluating the efficacy of paliperidone over 6 weeks, in 2508 participants with schizophrenia spectrum disorders. Twenty symptoms assessed across four time points were modelled using a panel graphical vector autoregression approach. Temporal networks were estimated for treatment and placebo groups. Network-level and symptom-level connectivity were compared using resampling-based permutation tests.
Results
Antipsychotic treatment was associated with significantly lower global symptom network connectivity than placebo treatment (18.92 v. 26.52; S = 7.60; p < 0.001). Specific inter-symptom connections were attenuated, most notably a reduced influence of ‘lack of spontaneity’ on other symptoms (0.97 v. 1.74; p < 0.001).
Conclusions
Antipsychotic treatment not only decreases symptom severity, but also disrupts dynamic interdependencies among symptoms. These findings suggest that effective treatment weakens maladaptive symptom coupling, offering new insights into the mechanisms of clinical improvement and potential targets for intervention.
Who your friends are shapes who your enemies are and vice versa. Starting with this premise, Mixed Blessings takes up two related research questions: how does a state's relational web of security assistance (amity) influence its relationships of threat (enmity), and how does a state's relational web of enmity influence its relationships of amity? Drawing on theories of alliance politics and deterrence theory, Kyle Beardsley uncovers the causes and consequences of security assistance through quantitative examination of the networked and relational nature of international politics. Qualitative assessments of the end of the Cold War-with particular attention to the proxy wars in Central America and Southern Africa-and recent developments in the Indo-Pacific further illustrate the mechanisms in play while also seeding the ground for ongoing inquiry. The lessons learned from the analyses directly bear on questions of American statecraft and the collapsing liberal international order.
Major depressive disorder and generalized anxiety disorder frequently co-occur, leading to heterogeneous presentations that complicate diagnosis and treatment. While diagnostic categories often obscure symptom variability, network approaches offer a powerful way to examine how symptoms relate to one another within and across conditions. By identifying symptom clusters, these methods can provide insights into potential mechanisms of comorbidity and symptom maintenance and may ultimately help guide more personalized treatment.
Methods
We examined patients (N = 33,675) seeking treatment for anxiety or depression through a message-based psychotherapy platform. Participants completed standardized measures of anxiety (GAD-7) and depression (PHQ-9) at baseline. We estimated a Gaussian Graphical Model of anxiety and depressive symptoms and identified overlapping symptom clusters using a modified Walktrap algorithm. We assigned patients to clusters based on presenting symptoms. In a subsample (n = 10,718), we examined the relationship between baseline cluster probabilities and three outcome trajectories over 12 weeks of treatment.
Results
We found four baseline symptom clusters relating to Affective Dysregulation, Worries, Neurovegetative symptoms, and Hyperarousal. Affective Dysregulation and Neurovegetative clusters were associated with poorer outcomes, whereas Worries and Hyperarousal were associated with recovery over partial improvement; Hyperarousal also differentiated recovery from non-response.
Conclusions
Symptom clusters derived from standard screening measures were associated with differential treatment trajectories. Targeting these symptom configurations may be particularly effective at disrupting multiple symptom pathways. Future research should examine whether personalized treatment strategies that consider symptom clusters based on simple screening in practice settings yield greater clinical improvement than traditional diagnostic categories.
This chapter introduces network analysis as an emerging approach in health research, providing tools to study the structure and dynamics of relationships between individuals, groups, or variables. It explains key concepts such as nodes, edges, centrality, and network density, and demonstrates how these measures capture the complexity of social, biological, or informational systems. Applications in epidemiology include modelling infectious disease transmission, understanding health behaviours, and identifying influential individuals or groups for interventions. Network analysis also supports systems-level understanding of comorbidities, genetic pathways, and healthcare delivery. Strengths of the method include its ability to visualise complex relationships, identify patterns not visible through traditional approaches, and generate novel insights into mechanisms of health and disease. Limitations include the need for high-quality relational data, complex analytical techniques, and challenges in interpretation. The chapter also highlights software tools and visualisation methods that make network analysis more accessible to researchers. Practical examples illustrate its use in mapping HIV transmission networks and analysing patterns of collaboration in healthcare teams. This chapter maps to syllabus section 3.2.13, which encourages knowledge of newer approaches including network and systems analysis.
The study of polarization in social networks is complicated by conceptual confusion: key forms of polarization include issue, ideological, affective, interactional, interpretive, and perceived polarization, but consensus remains elusive on which of these concepts are most important, how they are interrelated, and whether they should be considered problematic. In this article, we show how the communicative practices of the various actors in a given public debate can be analyzed to reveal the networked structures of discursive alignments and divergences and assess the degree of alliance or opposition between them, and how this analysis in turn provides a basis for the identification of polarization and its potential diagnosis as destructive. We address the challenge of assessing polarization by introducing the new analytical approach of practice mapping. Conceptually supported by practice theory, practice mapping advances beyond conventional social network analysis by no longer grounding its network analysis only in the direct network ties made by participants in social networks, but conceptualizing each participant’s broader patterns of action and interaction within the social network (including their engagement with other participants, but also their information sourcing, language choices, and other qualities of their participation) as that participant’s unique communicative practice—and then constructing and mapping the network of similarities between these practices for all participants. This serves as a key step towards identifying and analyzing patterns of polarization in public discourse. To illustrate this approach, we apply it to public posts on Facebook about the Voice to Parliament referendum in Australia. Our practice mapping was able not only to clearly identify the deeply opposed Yes and No campaigns, but also to show substantial distinctions between the highly centralized and unified No camp and the loose and uncoordinated discursive alliances supporting the Yes camp. Using this case study, we demonstrate the utility of practice mapping in assessing polarization in social networks.
This paper advances a methodological framework for the study of policy polarization. We conceptualize polarization as the structure of relationships among political and epistemic actors, measurable through the similarity of their policy statements. To generate these relational data, large language models (LLMs) are employed as scalable tools for extracting, summarizing, and synthesizing policy statements or positions from diverse textual sources, including debates, party platforms, interviews, and think tank publications. The resulting corpus is embedded into a shared vector space, and similarity measures between statements provide the basis for constructing multimodal networks that connect policy statements through semantic similarity and link them to candidates and think tanks. These networks enable the application of social network analysis, such as correspondence analysis, influence modeling, and structural comparison, to model alignments, divergences, and patterns of polarization. The framework contributes a replicable and extensible approach to analyzing policy polarization, integrating computational text processing with network-analytic models to capture the relational dynamics of political discourse.
Network analysis assessed the relationship between listening fatigue (Vanderbilt Listening Fatigue Scale; VFS) and foreign language learning anxiety (Foreign Language Classroom Anxiety Scale; FLCAS). Nodes represented the questions on each scale, and edges between nodes represented the strength and direction of the correlation between those questions/nodes. A simple correlation of the sum scores revealed a negative correlation: students reporting high fatigue reported low anxiety. This result may be due to the way in which cognitive resources are allocated (i.e., “ego depletion”). Analysis of the micro- and meso-level structure of the network revealed two distinct subsets of nodes (i.e., communities), with one community containing many of the FLCAS items (and the 5 nodes highest in strength) and the other community containing the VFS items and several items from the FLCAS that assessed confidence in using L2 rather than anxiety in learning L2. Additional ways that network science can be used to increase our understanding of language learning are discussed.
Mental disorders are major contributors to the global burden of disease and may show correlated incidence patterns across countries. We characterized the country-level ecological network of age-standardized incidence rates for 10 mental disorders, identified statistically central disorders and examined how individual countries influenced estimated network connectivity. Data for 204 countries and territories, including Sociodemographic Index values, were obtained from the Global Burden of Disease Study 2023. A regularized network model using the mgm framework estimated conditional associations among country-level variables. Strength centrality and case-deletion delta-centrality analyses assessed disorder connectedness and country influence, with bootstrap procedures evaluating stability. Approximately 400 million incident cases of the studied disorders were estimated globally in 2023. Anorexia nervosa and bipolar disorder had the highest strength centrality, indicating broader conditional connections with other disorders. Australia, the United States, Iran, China and Finland showed relatively large delta-centrality values, suggesting greater influence on estimated centrality than most countries. Strength centrality stability was acceptable but modest. These findings provide a descriptive, hypothesis-generating view of how modeled incidence rates covary across countries and should not be interpreted as individual-level comorbidity, causal influence or direct policy priority.
Attention-deficit hyperactivity disorder (ADHD) has been associated with compulsive sexual behaviours, including problematic pornography use. However, symptom-level mechanisms underlying this relationship remain poorly characterised, particularly across diverse demographic groups.
Aims
To identify key ADHD symptoms that bridge to compulsive sexual behaviour phenotypes (compulsive sexual behaviours and problematic pornography use) and examine whether symptom-level associations differ across sex, gender identity and age groups.
Method
This cross-sectional study analysed data from the International Sex Survey (2021–2022). Participants completed the Adult ADHD Self-Report Screening Scale, Compulsive Sexual Behaviour Disorder Scale and Problematic Pornography Consumption Scale. Gaussian graphical models and Bayesian networks were used to assess symptom-level relationships. Centrality and bridging indices were computed. Network comparison tests were also used to assess for any differences in network invariance and global strength across multiple demographic subgroups. Directed acyclic graphs were constructed to consider potential causal pathways.
Results
Among 82 243 participants (48 987 men (59.6%), 33 245 women (40.4%), mean age 33.1 years), ADHD symptoms of inattention and hyperactivity–impulsivity emerged as central, bridging and directionally plausible nodes. Network comparisons revealed demographic differences in overall network strength, with men and cisgender individuals exhibiting higher frequencies of association. Nonetheless, items relating to both inattention and hyperactivity–impulsivity consistently emerged as central across all population subgroups.
Conclusions
The finding suggesting that ADHD symptoms of inattention and hyperactivity–impulsivity are key drivers of compulsive sexual behaviours across global populations and multiple sociodemographic characteristics underscores the relevance of transdiagnostic mechanisms and suggests use of targeted interventions addressing executive dysfunction and reward dysregulation in ADHD.
Symptom network analysis is now commonly used in psychopathology research. Network analysis results in networks with symptoms represented as nodes, while edges represent conditional associations between these. Direct causal relations between symptoms will produce nonzero conditional associations, but these associations can also be produced in other ways. In this chapter, Borsboom discusses six plausible mechanisms that could produce edges in symptom networks. The first is resource competition, where the presence of a symptom depletes resources, which causes another symptom to arise. The second is evidential overlap, in which judgments central to different symptoms involve a subjective assessment of the same evidence. The third is shared mechanisms, in which symptomatology involves processes that are shared among different symptoms. The fourth are consistency drives, which arise when individuals are prone to align their cognitions, affect states, and behavior. The fifth are statistical processes involved in research design and analysis (marginalization and conditioning). The sixth is the presence of unobserved common causes that affect multiple symptoms at the same time. The author argues that, in realistic situations, the mechanisms in question are not mutually exclusive, which preempts standard scientific approaches that pit one model against another to derive critically divergent predictions. Instead, making sense of symptom networks will require more advanced theory development and modeling.