Mental health care in low- and middle-income countries is constrained by a shortage of trained professionals. To address this gap, a ten-module online training program based on the WHO Mental Health Gap Action Programme Intervention Guide (mhGAP-IG) was developed and evaluated across four Ethiopian public universities. A pre-post mixed-methods study was conducted among 494 students from four programs. Knowledge, attitudes, and clinical skills were assessed using standardized instruments, including the Mental Illness Clinicians’ Attitudes (MICA-2) scale and Enhancing Assessment of Common Therapeutic Factors (ENACT) tool. Post-training assessment showed statistically significant improvements: mean knowledge scores increased from 72.2% (SD 22.7) to 88.3% (SD 20.3), t (494) = 13.95, 95% CI [13.9, 18.4], (P < .001). Attitudes improved significantly, from a mean MICA score of 44.4 (SD 9.8) to 41.9 (SD 11.1), t (213) = -4.120, 95% CI [-3.7, -1.3], (P < .001). Clinical skills of students showed significant gains with a mean ENACT score increasing from 29.8 (SD 2.9) to 38.4 (SD 6.4) with a large effect size (P < .001, Cohen’s d = 1.24). The training improved knowledge, clinical skills, and attitudes, demonstrating potential as a feasible, sustainable, and scalable approach to strengthening mental health capacity among non-specialist health professionals.









